ABSTRACT
AIM OF THE STUDY: The aim of this study was to determine the prevalence of cannabis and tobacco use in a population attending a Methadone Center. METHODS: We studied 49 patients over a 3-month period. Urine samples were obtained at three different times from each patient for analysis. We measured urinary cannabinoids using an immunopolarization assay to identify cannabinoid use. Cotinine concentrations were quantified in urine using a colorimetric assay to assess total urinary nicotine metabolites. RESULTS: The prevalence of cannabis use was high in this population. Urinary cannabinoids were present in 63% of the samples. Similarly 90% had high-urinary cotinine concentrations. CONCLUSION: Measurement of urinary biomarkers showed that tobacco and cannabis use was high among patients attending a Methadone Center.
Subject(s)
Marijuana Abuse/epidemiology , Marijuana Abuse/urine , Opioid-Related Disorders/complications , Opioid-Related Disorders/drug therapy , Smoking/epidemiology , Smoking/urine , Substance Abuse Detection/methods , Substance Abuse Treatment Centers/statistics & numerical data , Adult , Biomarkers/urine , Colorimetry , Comorbidity , Cotinine/urine , Depression/complications , Female , Fluorescence Polarization Immunoassay , France/epidemiology , Humans , Longitudinal Studies , Male , Marijuana Abuse/complications , Population Surveillance , Prevalence , Risk Factors , Time FactorsABSTRACT
A 55 year old man, hypothyroid from previous thyroidectomy, presented with angina due to tracheal compression by a tumour of the posterior superior mediastinum. The preoperative work-up was negative. An aneurysm of a retrooesophageal subclavian artery was found at exploratory right thoracotomy in January 1977. This was resected and arterial reconstruction with a dacron graft was performed. The long term post operative clinical and angiographic results are satisfactory. The medical literature of this rare condition is reviewed.