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1.
Kyobu Geka ; 64(12): 1071-5, 2011 Nov.
Article in Japanese | MEDLINE | ID: mdl-22187867

ABSTRACT

The dual puncture is one of the diseaseful complications at the induction of the epidural anesthesia, which causes severe symptoms of intracranial hypotension such as headache and nausea. The clinical courses of 3 patients with the dual puncture symptoms after pulmonary resections were retrospectively reviewed, and the effect of the continuous epidural saline infusion treatment (CESI) for the dual puncture was evaluated. Pneumococcal empyema developed in 1 patient who had been treated with conservative management. In contrast, the symptoms of the others who were treated with the CESI were quickly recovered or were effectively prevented. This report strongly suggested that the CESI was convenient and effective treatment for dual punctune symptoms by suppressing the cerebrospinal fluid leakage by elevation of the fluid pressure in the extradural space.


Subject(s)
Anesthesia, Epidural/adverse effects , Post-Dural Puncture Headache/therapy , Adenocarcinoma/surgery , Aged , Epidural Space , Female , Humans , Lung Neoplasms/surgery , Pneumonectomy , Retrospective Studies , Sodium Chloride/administration & dosage
2.
Lung Cancer ; 57(3): 311-6, 2007 Sep.
Article in English | MEDLINE | ID: mdl-17509726

ABSTRACT

PURPOSE: To identify the factors involved in lymph node metastasis, 604 clinical stage I non-small cell lung cancer cases were studied. MATERIALS AND METHODS: Age, sex, Brinkmann Index (BI), histopathological type, histopathological differentiation degree, tumor size and CEA value were studied as factors involved in lymph node metastasis for 604 cases that were diagnosed to be clinical stage I (T1-T2N0M0; 1997 TNM categorization) non-small cell lung cancer. RESULTS: Lymph node metastasis was observed in 161 cases (27%). The factors involved in lymph node metastasis included the degree of histopathological differentiation and the tumor size. While the metastasis rate was less than 10% in well-differentiated cancers (even when the tumor size exceeded 4cm), in moderately differentiated and poorly differentiated cancers, the lymph node metastasis rate increased in proportion to tumor size. CONCLUSION: In stage I non-small cell lung cancer cases, cases with a low probability of lymph node metastasis are well-differentiated cancers. In these cases, lymph node dissection may be omitted in surgery (reduction surgery), and such cases may thus be good subjects for undergoing either stereotactic body radiotherapy (SBRT) or particle therapy.


Subject(s)
Carcinoma, Non-Small-Cell Lung/pathology , Lung Neoplasms/pathology , Adult , Aged , Aged, 80 and over , Carcinoembryonic Antigen/blood , Carcinoma, Non-Small-Cell Lung/surgery , Female , Humans , Lung Neoplasms/surgery , Lymphatic Metastasis , Male , Middle Aged , Neoplasm Staging , Prognosis
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