Manganese-catalyzed intermolecular C-H/C-H coupling of carbonyls and heteroarenes.

Manganese-catalyzed intermolecular C-H/C-H coupling of carbonyls and heteroarenes has been developed. The presence of NaIO4 as an oxidant is crucial for the catalytic reaction. These new, inexpensive reaction conditions allow the gram-scale synthesis of α-heteroaryl carboxylic acids.