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Hypertens Pregnancy ; 34(2): 221-6, 2015 May.
Article in English | MEDLINE | ID: mdl-25774453

ABSTRACT

BACKGROUND: We present the case of very early onset pre-eclampsia, possibly aggravated by liquorice consumption. CASE: An 18-year-old healthy primigravida presented with high blood pressure and proteinuria at 18 weeks gestation. She had a strong family history of pre-eclampsia and was consuming considerable amounts of liquorice. A diagnosis of severe pre-eclampsia/hemolysis, elevated liver enzymes, and low platelet count was confirmed. The pregnancy was terminated. Extensive investigation ruled out underlying diseases and autopsy revealed a normal fetus. In three consequtive pregnancies, she developed milder forms of pre-eclampsia. CONCLUSION: In healthy women with a familial/genetic susceptibility for pre-eclampsia, liquorice consumption may aggravate the course of the disease.


Subject(s)
Glycyrrhiza/adverse effects , Pre-Eclampsia/chemically induced , Pre-Eclampsia/diagnosis , Abortion, Therapeutic , Adolescent , Female , Genetic Predisposition to Disease , Humans , Pregnancy , Pregnancy Trimester, Second , Proteinuria/chemically induced
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