[Hypotonic shock reaction as quality control marker for platelet concentrates]. / Die hypotone Belastbarkeit als Qualitätskontrollmarker für Thrombozytenkonzentrate.

Ten years of quality control in routine have led to a standardized platelet concentrate (PC). Mean parameters of the preparations are in the range of pH 6.7-7.3, (1.0-1.5) x 10(9)/ml platelet concentration, 80 x 10(9) platelets/PC and 2 x 10(7) leukocytes/PC. To judge the function of PCs, three methods were compared: the morphologic score, platelet aggregation tests, and the hypotonic shock reaction. The result is: The hypotonic shock reaction is a simple, well reproducible and sensitive method to judge the cell integrity.