ABSTRACT
BACKGROUND: porocarcinoma is a rare sort of skin cancer developing from sweat glands. Its clinical course and management are not well understood. OBJECTIVES: the current meta-analysis is to address the presentation and management of porocarcinoma. DATA SOURCES: Web of Science, PubMed, MEDLINE on OVID and Google scholar were searched for English-language studies published before December 1, 2016. RESULTS: The review of literature revealed 453 cases. From which 222 (49%) cases were male and female were 231 (51%). The mean age was 67.57 years. The mean duration of presentation was 5.57 years ranging from 4 days to 60 years of age. The most common site of affection is the head and neck (39.9%) followed by lower extremity (33.9%). Mass and nodule are the most common modes of presentation. Metastasis occurred at presentation in 110 (31%) cases. The most common organ to which porocarcinoma metastizes is the nearby lymph node (57.7%). CONCLUSIONS: Porocarcinoma is an aggressive skin cancer. Surgery is the main modality of treatment. SYSTEMATIC REVIEW REGISTRATION NUMBER: reviewregistry233.
ABSTRACT
INTRODUCTION: Subacute thyroiditis is a self-limited, inflammatory viral thyroid disease which presents with neck pain, usually accompanied by systemic symptoms. On the other hand, thyroid storm is a clinical condition of severe sudden hyperthyroidism accompanied by physiologic de-compensation. We presented a 29-year-old male with features of subacute thyroiditis and thyroid storm who is the third reported case managed by steroid, beta-blocker and analgesics. CONCLUSION: subacute thyroiditis may present with thyrotoxic crisis which respond dramatically to corticosteroid therapy.
