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Gan To Kagaku Ryoho ; 50(5): 635-637, 2023 May.
Article in Japanese | MEDLINE | ID: mdl-37218328

ABSTRACT

Drug-induced interstitial lung disease(DILD)is a possible complication of many anticancer drugs. When DILD occurs during breast cancer treatment, choosing the right drug for subsequent treatment is often difficult. In our first case, the patient developed DILD during dose-dense AC(ddAC)therapy; however, the disease resolved with steroid pulse therapy, and the patient underwent surgery without disease progression. In the second case, a patient on anti-HER2 therapy for recurrent disease developed DILD in response to docetaxel plus trastuzumab plus pertuzumab administered to treat T-DM1 after progressive disease. In this report, we describe a case of DILD that did not worsen and the patient had successful treatment outcome.


Subject(s)
Breast Neoplasms , Lung Diseases, Interstitial , Female , Humans , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Breast Neoplasms/drug therapy , Breast Neoplasms/surgery , Docetaxel/adverse effects , Lung Diseases, Interstitial/chemically induced , Lung Diseases, Interstitial/drug therapy , Receptor, ErbB-2 , Trastuzumab
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