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1.
Sloan Manage Rev ; 33(1): 15-26, 1991.
Article in English | MEDLINE | ID: mdl-10115662

ABSTRACT

Many articles exhort service firm managers to empower workers and first-line supervisors, exploit technology, focus on the customer, and, above all, provide outstanding service. This article proposes a framework to help you evaluate your company's competitive standing in each of these areas. It discusses four types of companies on a continuum, from the company that is simply "available for service" to the firm that delivers world class service. The authors focus on operations, the function that controls the service encounter, and apply the manufacturing strategy paradigm to services as a means of implementing change.


Subject(s)
Consumer Behavior , Economic Competition , Industry/organization & administration , Models, Theoretical , Operations Research , Organizational Culture , Organizational Objectives , Planning Techniques , Product Line Management/standards , Quality Control , United States
2.
Trans R Soc Trop Med Hyg ; 82(4): 532-7, 1988.
Article in English | MEDLINE | ID: mdl-2475928

ABSTRACT

A conserved repeated epitope, (NANP)3, of the circumsporozoite protein of Plasmodium falciparum has been identified previously as a putative target for artificially induced immunity to malaria. We examined the role of humoral responses to this epitope in acquired immunity to malaria in a rural African population. Seropositivity to (NANP)3 was slow to develop (9% positive in subjects aged 1-11 years; 88% in those of 30 years and above), and responses in younger subjects were transient. The poor response in younger subjects did not appear to be due to immunosuppression by concomitant blood stage parasitization. The relationship between levels of anti-(NANP)3 antibodies and parasitaemia changed from positive to negative with age. 126 subjects age 1-11 years were followed through an entire transmission season; those who were seropositive at the beginning ended the season with lower parasite rates (20% vs 59%) and experienced fewer episodes of clinical malaria (0.43 vs 0.67). However, the trend towards increasing susceptibility to clinical malaria in subjects entering the transmission season with lower levels of anti-(NANP)3 antibodies was modest, and combined cross-sectional and longitudinal data indicated that the humoral response to (NANP)3 did not play a major role in the development of immunity to clinical malaria in the population we studied.


Subject(s)
Antibodies, Protozoan/biosynthesis , Malaria/immunology , Oligopeptides/immunology , Plasmodium falciparum/immunology , Age Factors , Animals , Antimalarials/therapeutic use , Child , Child, Preschool , Dapsone/therapeutic use , Drug Combinations/therapeutic use , Epitopes/analysis , Gambia , Humans , Infant , Malaria/parasitology , Malaria/prevention & control , Middle Aged , Pyrimethamine/therapeutic use
3.
Am J Vet Res ; 44(6): 1108-11, 1983 Jun.
Article in English | MEDLINE | ID: mdl-6870015

ABSTRACT

The toxicity of fenbendazole, an anthelmintic for use in swine, was tested by feeding 8 growing pigs 2,000 mg of fenbendazole/kg of body weight daily for 14 days. A transient leukopenia developed on day 6, but values returned to base line on day 18, 4 days after discontinuation of dosing. Sorbitol dehydrogenase values were significantly (P less than 0.05) increased from day 4 and returned to base line on day 20. Marked gross or histopathologic lesions were not found.


Subject(s)
Benzimidazoles/toxicity , Fenbendazole/toxicity , Swine , Alkaline Phosphatase/analysis , Animals , Female , L-Iditol 2-Dehydrogenase/analysis , Leukopenia/chemically induced
4.
Am J Vet Res ; 44(6): 1112-6, 1983 Jun.
Article in English | MEDLINE | ID: mdl-6870016

ABSTRACT

The safety of fenbendazole, an anthelmintic for use in swine, was tested by feeding 0, 25, 75, or 125 mg of fenbendazole/kg of body weight for 5 days. A dose-related transient leukopenia developed on day 7, but values returned to base line on day 15. In the groups fed 75 or 125 mg, sorbitol dehydrogenase activity increased on day 3 but returned to base line on day 10. Significant gross or histopathologic lesions were not found.


Subject(s)
Benzimidazoles/toxicity , Fenbendazole/toxicity , Swine , Animals , Blood/drug effects , Female , L-Iditol 2-Dehydrogenase/analysis , Leukocyte Count , Phosphorus/blood , Swine/blood
5.
Dent Econ ; 73(5): 73-4, 1983 May.
Article in English | MEDLINE | ID: mdl-6582017
6.
Arch Environ Contam Toxicol ; 9(2): 193-206, 1980.
Article in English | MEDLINE | ID: mdl-7387187

ABSTRACT

A survey was conducted in 1975-1976 to determine the background levels of lead, cadmium, and mercury tissues of healthy swine, cattle, dogs, and horses from the midwestern United States. Blood, muscle, liver, and kidney were assayed from cattle and swine slaughtered at federal meat inspection plants and in dogs and horses obtained from local pounds and sales barns. A total of 959 samples for lead, 972 samples for cadmium, and 827 samples for mercury were analyzed. The maximum muscle lead concentration was less than 0.10 ppm in dogs and horses. Fourteen percent of the cattle muscle samples contained between 0.16 and 0.34 ppm lead. The blood lead concentration was generally lower than 0.10 ppm in cattle, swine and horses; however, in dogs 44% of the blood lead values were between 0.11 and 0.37 ppm. The liver and kidney lead content was generally less than 0.50 ppm in all species, and the maximum lead content detected in either tissue was less than 2.0 ppm. Elevated tissue levels of cadmium were observed in horses as compared to other species. While the maximum muscle cadmium content in cattle, swine, and dogs rarely exceeded 0.05 ppm, levels in excess of 0.06 ppm were found in all the 19 horse muscle samples. Blood cadmium levels in all species were near or below the detection limit of 0.005 ppm. The median cadmium concentration in liver and kidney was below 0.2 and 0.6 ppm, respectively, in cattle, swine, and dogs. However, in horses the median concentration was 20 times greater in liver and 4 times higher in kidney. The mercury concentrations in muscle and blood of all species were near or below the detection limit of 0.02 ppm. The median concentrations of mercury in liver and kidney, respectively, were: 0.02 ppm each in swine and cattle; 0.02 ppm and 0.05 ppm in dogs; and 0.12 ppm and 0.72 ppm in horses. The results suggest that exposure of animals to dietary or environmental lead, cadmium, and mercury in the midwestern United States is not significant. The specific cumulation of cadmium and mercury in tissues of horses suggests the need to explore the role these metals play in selective biological processes.


Subject(s)
Cadmium/analysis , Lead/analysis , Mercury/analysis , Animals , Cattle , Dogs , Horses , Swine , Tissue Distribution , United States
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