ABSTRACT
OBJECTIVE: To explore the effects of different intensity pulsed electromagnetic fields (PEMFs) on serum estradiol in ovariectomized rats. METHODS: Fifty female SD rats were randomly divided into five groups: sham-operated control (no PEMF treatment), ovariectomized control(no PEMF treatment),ovariectomized group I, II, III (PEMF treatment at 8 Hz frequency and 0.77 mT, 3.82 mT, 9.87 mT intensity, 40 min daily for 30 days). Except for the sham-operated control rats, a standardized ovariectomy was used on every rat of other groups. The serum estradiol(E2) of rats was assessed at 30 days after PEMF treatment. RESULTS: The E2 values of the SHAM control group were significantly higher than those of other four groups (P < 0.05 or P < 0.01), but the difference in E2 values was not significant among the other four groups (P > 0.05). CONCLUSION: PEMFs can not improve the serum estradiol level of ovariectomized rat, it shows that the therapeutical effect of PEMFs is not due to improve the serum estradiol level.
