ABSTRACT
To enhance the anti-biofouling properties and adsorption capability of poly(amidoxime) (PAO), vinylphosphonic acid (VPA, CH2[double bond, length as m-dash]CH-PO3H2) was polymerized on poly(acrylonitrile) (PAN) surface by plasma technique, followed by amidoximation treatment to convert the cyano group (-C[triple bond, length as m-dash]N) into an amidoxime group (AO, -C(NH2)[double bond, length as m-dash]N-OH). The obtained poly(vinylphosphonic acid)/PAO (PVPA/PAO) was used as an adsorbent in the uptake of U(vi) from seawater. The effect of environmental conditions on the anti-biofouling property and adsorption capability of PVPA/PAO for U(vi) were studied. Results show that the modified PVPA enhances the anti-biofouling properties and adsorption capability of PAO for U(vi). The adsorption process is well described by the pseudo-second-order kinetic model and reached equilibrium in 24 h. Adsorption isotherms of U(vi) on PVPA/PAO can be well fitted by the Langmuir model, and the maximum adsorption capability was calculated to be 145 mg g-1 at pH 8.2 and 298 K. Experimental results highlight the application of PVPA/PAO in the extraction of U(vi) from seawater.
ABSTRACT
BACKGROUND: Although cardiac troponin has been well established as diagnostic and prognostic makers for acute coronary heart disease, the prognostic value of elevated cardiac troponin in patients with intracerebral hemorrhage (ICH) was inconsistent and not systematically evaluated. HYPOTHESIS: We proposed the hypothesis that the practical utility of cardiac troponin levels for prediction of mortality and poor outcome in ICH patients. METHODS: A total of 1004 patients with ICH were retrospectively reviewed and qualified for further analysis from June 2012 to December 2015. The patients were divided into different groups based on measurements of cardiac troponin I (cTnI) at the time of admission and the following day. Multivariate Cox proportional hazards analysis were performed to determine the independent prognostic value of the cTnI for patients in-hospital mortality and poor outcomes, the receiver operator characteristic (ROC) analysis was performed to assess the predictive value of cTnI, ICH score, and combination of them. RESULTS: Serum cTnI level was an independent predictor in-hospital mortality (positive vs negative, HR (hazard ratios) = 3.44, 95% CI (confidence interval) 1.66-7.13, P < .001) and poor outcomes in patients with ICH (positive vs negative, HR = 6.69, 95% CI 4.25-10.52, P < .001). Addition of cTnI to ICH score significantly improved the prognostic discrimination for both in-hospital mortality and poor outcomes. CONCLUSION: Serum cTnI levels may be valuable as predictor for in hospital mortality and poor outcomes and may be useful in the risk stratification of ICH during hospitalization.
