[Alkaloid constituents from silkworm dropping of Bombyx mori].

OBJECTIVE: To extract and isolate chemical constituents from the total alkaloids of silkworm dropping (Can Sha) of Bombyx mori L. METHODS: Chemical constituents were isolated by column chromatography with macroporous adsorbent resin, ion-exchange resin and sephadex LH 20. The structures of the isolated compounds were determined by spectral means. RESULTS: Three compounds were isolated and identified as 1-deoxynojirimycin (1) , fagomine (2) , and 3-epifagomine (3) on the basis of their 1H-NMR, 13C-NMR spectra and ESIMS data. CONCLUSION: Compounds 1-3 are isolated and identified from Can Sha for the first time.