ABSTRACT
The TiO2 nanotube has been anticipated for potential application for cardiovascular implanted devices for its excellent drug loading/release function and biocompatibility. However, its mechanical behavior has rarely been studied as the cardiovascular devices. The tube length is a crucial factor which not only decides the drug loading ability but also influences the devices' mechanical behavior. Therefore, in this work, the TiO2 nanotubes with different tube length (NT2, NT4 and NT6) were fabricated, and their surface energy, residual stress, tensile tolerability and blood flow shear stress tolerability were determined, respectively. The results showed that there were no significant difference for each film samples on surface energy, tensile tolerability and blood flow shear stress tolerability, while NT6 obtained the smallest residual stress. These results indicated that longer TiO2 nanotubes not only meant loading more drugs but also better mechanical properties for surface modification of cardiovascular devices.
