Characteristics and outcomes for 61 cats that underwent either surgery or stereotactic radiotherapy as treatment for intracranial meningioma (2005-2017).

OBJECTIVE: To report clinical features and outcomes of cats undergoing either stereotactic radiotherapy (SRT) or surgical excision for the treatment of intracranial meningioma. ANIMALS: 61 client-owned cats. METHODS: Medical records were retrospectively reviewed of cats with intracranial meningiomas that were treated with surgical removal and/or SRT between 2005 and 2017. Signalment, clinical signs, duration of clinical signs, diagnostic imaging reports, histopathology reports, treatment protocol, complications, recurrence or progression, and survival time were obtained from the medical record and through follow-up phone calls. RESULTS: Of the 61 patients, 46 had surgery, 14 had SRT, and 1 had surgery followed by SRT for initial treatment. Significantly more cats that underwent surgery had peritreatment complications compared to the SRT group (P < .0001). Cats that received surgery initially had a significantly longer median survival time (MST) of 1,345 days compared to the MST of 339 days for the SRT cats (P = .002). Fourteen (30%) cats in the surgery group and 4 cats in the SRT group (28%) had MRI- or CT-confirmed tumor regrowth or new tumor growth (P = 1.00). Five cases that had SRT for subsequent recurrence had an MST of 700 days (range, 335 to 1,460 days) after the last treatment. CLINICAL RELEVANCE: SRT proved to be a safe, alternative treatment option for feline patients with intracranial meningiomas; however, the survival times with surgery alone were significantly longer. SRT for the treatment of recurrence following initial surgery may show promising results.

Diagnostic accuracy of optical coherence tomography for surgical margin assessment of feline injection-site sarcoma.

The invasive, locally aggressive nature of feline injection-site sarcomas (FISSs) poses a unique challenge for surgeons to obtain complete margins with surgical excision. Optical coherence tomography (OCT), an imaging technology that uses light waves to generate real-time views of tissue architecture, provides an emerging solution to this dilemma by allowing fast, high-resolution scanning of surgical margins. The purpose of this study was to use OCT to assess surgical margins of FISS and to evaluate the diagnostic accuracy of OCT for detecting residual cancer using six evaluators of varying experience. Five FISSs were imaged with OCT to create a training set of OCT images that were compared with histopathology. Next, 25 FISSs were imaged with OCT prior to histopathology. Six evaluators of varying experience participated in a training session on OCT imaging after which each of the evaluators was given a dataset that included OCT images and videos to score on a scale from cancerous to non-cancerous. Diagnostic accuracy statistics were calculated. The overall sensitivity and specificity for classification of OCT images by evaluators were 78.9% and 77.6%, respectively. Correct classification rate of OCT images was associated with experience, while individual sensitivities and specificities had more variation between experience groups. This study demonstrates the ability of evaluators to correctly classify OCT images with overall low levels of experience and training and also illustrates areas where increased training can improve accuracy of evaluators in interpretation of OCT surgical margin images.

Comparison of perioperative and short-term postoperative complications of gastrointestinal biopsies via laparoscopic-assisted technique versus laparotomy.

This retrospective report describes perioperative and short-term postoperative complications of gastrointestinal biopsies obtained via a laparoscopic-assisted technique compared with laparotomy in a population of 60 client-owned dogs and cats with naturally occurring gastrointestinal disease. The medical records were examined for patients that underwent surgery for diagnostic gastrointestinal biopsies. Data were collected regarding perioperative complications such as hypotension, hypercarbia, and hypoxemia, and short-term postoperative complications including seroma and incisional infection/inflammation. The perioperative complication rate was 17.6% for the laparoscopically assisted group and 16.6% for the control group. The short-term postoperative complication rate was 5.9% for the laparoscopically assisted group and 0% for the control group. There was a 0% rate of intestinal dehiscence. There were no statistically significant differences in complication rates between the 2 groups, showing that laparoscopic-assisted gastrointestinal biopsies can be performed with acceptable perioperative and short-term postoperative complication rates.

Comparaison des complications péri-opératoires et postopératoires à court terme découlant des biopsies gastro-intestinales à l'aide d'une technique assistée par laparascopie par rapport à la laparotomie. Ce rapport rétrospectif décrit les complications péri-opératoires et postopératoires à court terme de biopsies gastro-intestinales obtenues à l'aide d'une technique assistée par laparascopie comparativement à une laparatomie dans une population de 60 chiens et chats appartenant à des clients présentant une maladie gastro-intestinale naturelle. Les dossiers médicaux ont été examinés pour les patients qui ont subi une chirurgie pour des biopsies gastro-intestinales de diagnostic. Les données ont été recueillies concernant les complications péri-opératoires, comme l'hypotension, l'hypercarbie et l'hypoxémie ainsi que les complications postopératoires à court terme, incluant le sérome et l'infection/inflammation de l'incision. Le taux de complication péri-opératoire était de 17,6 % pour le groupe assisté par laparoscopie et de 16,6 % pour le groupe témoin. Le taux de complication postopératoire à court terme était de 5,9 % pour le groupe assisté par laparascopie et de 0 % pour le groupe témoin. Le taux de déhiscence intestinale était de 0 %. Il n'y avait aucune différence statistique des taux de complication entre les deux groupes, ce qui indique que les biopsies gastro-intestinales assistées par laparoscopie peuvent être réalisées avec des taux acceptables de complications péri-opératoires et postopératoires.(Traduit par Isabelle Vallières).

Upper thoracic disc disease (T1-T9) in large-breed dogs.

The purpose of this study was to identify large-breed dogs with intervertebral disc disease (IVDD) in the upper thoracic region (thoracic vertebrae 1-9 [T1-T9]). Medical records of all dogs that were diagnosed with IVDD on MRI between February 2008 and September 2011 were reviewed. Of 723 dogs diagnosed with IVDD based on MRI, 527 (72.9%) were small-breed dogs. There were 21 (10.7%) large-breed dogs with IVDD in the T1-T9 region, whereas no small-breed dogs were identified with lesions in that region. The most common upper thoracic lesion sites were T2-T3 (33.3%) and T4-T5 (25.9%). The majority of dogs with T1-T9 lesions were German shepherd dogs (52.4%). Larger, older dogs were more likely to have T1-T9 lesions and more likely to have multiple regions with IVDD, in particular German shepherd dogs (35.1%). Dogs with T1-T9 IVDD were more likely to have IVDD in another region (66.7%). All large-breed dogs presenting with T3-L3 myelopathy should have diagnostic imaging performed of their entire thoracic and lumbar spine.

Comparison of two radiographic techniques for evaluation of hip joint laxity in 10 breeds of dogs.

OBJECTIVE: To evaluate hip joint laxity in 10 breeds of dogs via 2 radiographic techniques. ANIMALS: 500 clinically normal dogs. DESIGN: Prospective study. PROCEDURE: Radiographs obtained via routine hip joint evaluations performed in sedated dogs of 10 popular breeds were randomly selected from a database. Measurements of distraction index (DI) and hip-extended index (HEI) on 1 hip joint radiograph randomly chosen from each dog were made. RESULTS: Mean age of dogs was 20.7 months. Mean HEI was 0.17 (range, 0.0 to 0.72) and mean DI was 0.44 (range, 0.07 to 0.96). Borzois had uniformly tight hip joints as judged by use of both methods and were considered the gold standard by which hip joint laxity was judged (all Borzois had DI < or = 0.32). Overall, DI was significantly greater than HEI. Within each breed, mean DI was always greater than mean HEI. Significant differences were detected among breeds for HEI; however, compared with DI, the magnitude of differences among breeds was less. CONCLUSIONS AND CLINICAL RELEVANCE: Distraction radiography detected the greatest range and magnitude of passive hip laxity in the 10 breeds of dogs. The difference in values between breeds known to have high prevalence of canine hip dysplasia and those in Borzois was greater for DI than for HEI. Breeds must be evaluated individually because of inherent differences in hip joint laxity.