ABSTRACT
The study was carried out on 15 children with pollinosis. The children were treated with "Pollinex-Bencard" before the pollen season. We looked for changes of serum IgE levels and percentages of T (CD3) cells and their subsets CD4, CD8. After immunotherapy we observed a significant decrease of CD3, CD4 and CD8 cells, whereas no statistical difference was observed in the CD4/CD8 ratio. Three months after immunotherapy, serum IgE levels were significantly elevated, while after 9 months, markedly decreased.
Subject(s)
Allergens/therapeutic use , Glutaral/therapeutic use , Immunotherapy , Plant Extracts/therapeutic use , Pollen , Rhinitis, Allergic, Seasonal/therapy , Tyrosine/therapeutic use , Adolescent , Antigens, Plant/therapeutic use , CD4-CD8 Ratio , Child , Drug Combinations , Female , Humans , Immunoglobulin E/blood , Male , Rhinitis, Allergic, Seasonal/immunology , T-Lymphocytes/immunologyABSTRACT
Cow's milk has been considered as a possible trigger of the autoimmune response that destroys pancreatic B-cells, thus causing insulin dependent diabetes mellitus. We investigated 46 children with IDDM. In this group we showed an increased total IgE in 58.6% of cases and the presence of specific IgE antibodies induced by milk allergens in 32.5% of cases. These results suggests that antibodies probably play an important role in IDDM pathogenesis.
Subject(s)
Allergens , Diabetes Mellitus, Type 1/immunology , Immunoglobulin E/immunology , Milk/immunology , Adolescent , Animals , Child , Child, Preschool , Female , Humans , MaleSubject(s)
Allergens/immunology , Dermatitis, Atopic/immunology , Epitopes , Immunoglobulin E/blood , Adolescent , Child , Child, Preschool , Dermatitis, Atopic/diagnosis , Female , Humans , Male , Skin TestsSubject(s)
Antibody Specificity , Asthma/immunology , Immunoglobulin E/blood , Adolescent , Asthma/diagnosis , Child , Child, Preschool , Female , Humans , Infant , Male , Skin TestsABSTRACT
A case is presented of a 12-year-old girl with skin changes existing since birth which (in spite of the lack of changes in hair structure) were regarded as a coexistence of generalized ichthyosiform erythrodermia and atopic dermatitis, and which were diagnosed on the basis of literature data as Netherton's syndrome. Several weeks of treatment with non-steroid ointments, new generation antihistamines with the use of elimination diet gave an evident improvement and made possible her discharge in fairly good general condition, with suggested further treatment in the allergy outpatient clinic.
