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1.
Am J Obstet Gynecol ; 203(5): 514.e1-7, 2010 Nov.
Article in English | MEDLINE | ID: mdl-20869691

ABSTRACT

OBJECTIVE: The purpose of this study was to assess the prevalence of pelvic floor disorders and sexual function in survivors of gynecologic cancer. STUDY DESIGN: We surveyed survivors of gynecologic cancer (survivors) and women seeking gynecologic care (control patients) who were >30 years old. All survivors were disease- and treatment-free for ≥1 year. Validated questionnaires were used to evaluate pelvic floor disorders. RESULTS: One hundred eight control patient and 260 survivor questionnaires were completed. A high prevalence of pelvic floor disorders was observed in both groups; 56% of control subjects and 70% of survivors reported moderate to severe urinary incontinence (P > .05). Survivors were more likely to experience fecal incontinence (42% vs 32%; P = .02). Survivors reported less sexual desire (P = .04) and less ability to climax (P = .04), despite no difference in dyspareunia. CONCLUSION: Fecal incontinence and sexual dysfunction are significant problems in survivors of gynecologic cancer.


Subject(s)
Fecal Incontinence/epidemiology , Genital Neoplasms, Female/physiopathology , Pelvic Floor/physiopathology , Pelvic Organ Prolapse/epidemiology , Sexual Dysfunction, Physiological/epidemiology , Sexual Dysfunctions, Psychological/epidemiology , Urinary Incontinence/epidemiology , Adult , Aged , Fecal Incontinence/physiopathology , Female , Health Surveys , Humans , Libido , Middle Aged , Pelvic Organ Prolapse/physiopathology , Prevalence , Quality of Life , Sexual Dysfunction, Physiological/physiopathology , Sexual Dysfunctions, Psychological/physiopathology , Surveys and Questionnaires , Survivors , Urinary Incontinence/physiopathology
2.
Int J Gynecol Pathol ; 29(4): 398-401, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20567156

ABSTRACT

A 55-year-old female equestrian presented with a 3.5 cm painful left perineal mass. Histologic examination of the excised mass showed a poorly circumscribed mesenchymal proliferation involving fibroadipose and fibrous tissue. The lesion consisted of a bland spindle cell proliferation with areas of fat necrosis, hemosiderin-laden macrophages, multinucleated histiocytes, and extracellular hyalinization with degenerative features. Immunohistochemical studies showed vimentin positivity and no staining for actin, desmin, and CD34. On the basis of clinical, morphologic, and immunostaining findings, the lesion was consistent with a diagnosis of perineal nodular induration. This lesion has been described almost exclusively in avid male cyclists with repetitive perineal trauma. A similar etiology of longstanding and repetitive perineal trauma from horseback riding is postulated for this case. Perineal nodular induration should be considered in the differential diagnosis of perineal masses in women with persistent perineal trauma, such as equestrianism, as well as other similar sport activities.


Subject(s)
Perineum/pathology , Soft Tissue Neoplasms/pathology , Wounds and Injuries/pathology , Female , Histocytochemistry , Humans , Middle Aged , Perineum/surgery , Soft Tissue Neoplasms/surgery
3.
J Pediatr Surg ; 40(1): 98-102, 2005 Jan.
Article in English | MEDLINE | ID: mdl-15868566

ABSTRACT

BACKGROUND/PURPOSE: Because blunt thoracic aortic injury is rare in children, a high index of suspicion is needed to identify this injury. The purpose of this study was to use a large national trauma database to define the risk factors for blunt thoracic aortic injury in children. METHODS: Using the National Trauma Database, the authors compared patient demographics, mechanism of injury, and associated injuries between children sustaining blunt trauma with and without a thoracic aortic injury. Factors independently associated with this injury were identified using multivariate methods. RESULTS: Among 26,940 children with a blunt mechanism of injury, 34 (0.1%) children sustained a thoracic aortic injury, 14 (41%) of whom died. Thoracic aortic injuries were independently associated with age, injury sustained as an occupant in a motor vehicle crash, and severe injuries (Abbreviated Injury Scale value of > or =3) involving the head, thorax (other than aorta), abdomen, and lower extremities. CONCLUSIONS: Older children involved in a motor vehicle crash with severe head, torso, and lower extremity injuries are a group at high risk for injury to the thoracic aorta. These easily identifiable risk factors may facilitate more rapid identification of this rare and potentially fatal injury.


Subject(s)
Aorta, Thoracic/injuries , Wounds, Nonpenetrating/epidemiology , Accidents, Traffic/statistics & numerical data , Adolescent , Age Factors , Child , Databases as Topic , Female , Humans , Male , Risk Factors , United States/epidemiology , Vascular Surgical Procedures , Wounds, Nonpenetrating/mortality , Wounds, Nonpenetrating/surgery
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