ABSTRACT
CONTEXT: Dentinal hypersensitivity (DH) is a commonly encountered problem. Several products are used in management of DH with varying results. Need is felt in dentistry for a material that chemically reacts, physically occludes and adheres intimately to dentinal tubules to reduce the possibility of its recurrence. One such material is calcium sodium phosphosilicate-Novamin. AIM: To evaluate an efficacy of a 5% calcium sodium phosphosilicate (Novamin SHY NM) containing dentifrice compared to placebo for the relief of DH. SETTINGS AND DESIGN: Outpatients visiting Dept of Periodontics, Yenepoya Dental College with DH were deemed eligible for this case-control clinical trial after an informed consent. MATERIALS AND METHODS: 30 patients having at least 2 sensitive teeth with a VAS (Visual Analogue Scale) of >3 cm after air blast stimulation, qualified to participate in the study. Test (SHY NM toothpaste containing 5% calcium sodium phosphosilicate) and control (Pepsodent toothpaste without a desensitizing agent) groups, each containing 15 participants, were subjected to cold water and air blast stimulation for an assessment of DH at baseline, 6 th and 8 th week using VAS. STATISTICAL ANALYSIS USED: Unpaired t-test and repeated measures ANOVA. RESULTS: 5% Novamin containing dentifrice significantly reduced DH within 6 th and 8 th week of usage when compared to a placebo dentifrice. CONCLUSIONS: A Novamin containing dentifrice significantly reduced DH when compared to a placebo dentifrice.
Subject(s)
Dentifrices/therapeutic use , Dentin Desensitizing Agents/therapeutic use , Dentin Sensitivity/drug therapy , Glass , Adolescent , Adult , Aged , Air , Case-Control Studies , Cold Temperature , Dentin/drug effects , Follow-Up Studies , Humans , Middle Aged , Pain Measurement , Placebos , Single-Blind Method , Toothpastes/therapeutic use , Treatment Outcome , Water , Young AdultABSTRACT
UNLABELLED: Vaccination against periodontal diseases is an innovative approach to combating periodontal diseases. Although discussed briefly some 50 years ago by Bibby, it has been popularized with the late twentieth century technologies and current understanding of periodontal microbiology. This review discusses the potential for a vaccine against periodontitis. CLINICAL RELEVANCE: A vaccine is a possible protection strategy for primary prevention of periodontitis.