Long-term course of binge eating disorder and bulimia nervosa: relevance for nosology and diagnostic criteria.

OBJECTIVE: To present the twelve-year outcome of binge eating disorder (BED) in 68 female inpatients compared to bulimia nervosa, purging type (BN-P; N = 196). METHOD: Self and expert ratings focused on the beginning of therapy and the 12-year follow-up. RESULTS: 36% of BED and 28.2% of BN-P patients still received an eating disorder diagnosis at follow-up. Differences between groups were small (Eating Disorder Inventory, Structured Inventory for Anorexic and Bulimic Syndromes, Hopkins Symptom Checklist, Beck Depression Inventory). Similar predictors for BED and BN-P were identified. Psychiatric comorbidity was the predominant predictor of poor outcome in both diagnoses. Predictors for BED outcome were body dissatisfaction, sexual abuse, and impulsivity; self-injury predicted BN-P outcome. CONCLUSION: Course, outcome, and mortality were similar for BED and BN-P. Both disorders had psychiatric comorbidity as the main predictor of outcome, and there was a diagnostic shift between BED and BN-P over time, pointing to their nosological proximity. Data are relevant for the formulation of DSM-V and ICD-11 diagnostic criteria.

Twelve-year course and outcome predictors of anorexia nervosa.

OBJECTIVE: The current study presents the long-term course of anorexia nervosa (AN) over 12 years in a large sample of 103 patients diagnosed according to criteria in the 4th ed. of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). METHOD: Assessments were made at the beginning of therapy, at the end of therapy, at the 2-year follow-up, at the 6-year follow-up, and at the 12-year follow-up. Self-rating and an expert-rating interview data were obtained. RESULTS: The participation rate at the 12-year follow-up was 88% of those alive. There was substantial improvement during therapy, a moderate (in many instances nonsignificant) decline during the first 2 years posttreatment, and further improvement from 3 to 12 years posttreatment. Based on a global 12-year outcome score, 27.5% had a good outcome, 25.3% an intermediate outcome, 39.6% had a poor outcome, and 7 (7.7%) were deceased. At the 12-year follow-up 19.0% had AN, 9.5% had bulimia nervosa-purging type (BN-P), 19.0% were classified as eating disorder not otherwise specified (EDNOS). A total of 52.4% showed no major DSM-IV eating disorder and 0% had binge eating disorder (BED). Systematic-strictly empirically based-model building resulted in a parsimonious model including four predictors of unfavorable 12-year outcome explaining 45% of the variance, that is, sexual problems, impulsivity, long duration of inpatient treatment, and long duration of an eating disorder. CONCLUSION: Mortality was high and symptomatic recovery protracted. Impulsivity, symptom severity, and chronicity were the important factors for predicting the 12-year outcome.