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Bioorg Med Chem Lett
; 15(8): 2093-6, 2005 Apr 15.
Article
in English
| MEDLINE
| ID: mdl-15808475
ABSTRACT
Novel derivatives of Tolterodine (1) and Oxybutynin (2) have been designed using conformationally restricted azabicyclics as replacement for open-chain amines. The synthesis and structure-activity relationships are presented.