ABSTRACT
Coats' Disease is an idiopathic condition of the eye affecting young children although it can be seen in adults. Most patients present early in life with unilateral decreased vision, strabismus or leukocoria. The most important differential diagnosis is unilateral retinoblastoma. In this study we report a case of coat's disease in an young girl, and evaluate histopathological and clinical findings.
Subject(s)
Diagnosis, Differential , Retinal Telangiectasis/diagnosis , Retinoblastoma/diagnosis , Conjunctiva/pathology , Eye/pathology , Female , Humans , Infant , Intraocular Pressure , Pathologists/education , Retinal Detachment , Retinal Telangiectasis/diagnostic imaging , Retinal Telangiectasis/physiopathology , Retinoblastoma/diagnostic imaging , Retinoblastoma/physiopathology , Tomography, X-Ray Computed , UltrasonographyABSTRACT
We report a rare presentation of an initially misdiagnosed case of a pseudotumor, which on histopathology was diagnosed as bilateral breast metastases of lobular carcinoma involving multiple extraocular muscles. A 61-year-old lady presented with external ophthalmoplegia and diplopia. Incisional biopsy was performed using a lid crease approach and the patient received radiotherapy and hormonal therapy. Following prolonged hormonal therapy, complete remission was achieved, with improvement in ocular motility and resolution of diplopia, about 18 months after the initial presentation. Multiple extraocular muscle involvement by breast carcinoma metastasis is very rare and should be considered in the differential diagnosis, especially in patients with a prior history of breast carcinoma.
Subject(s)
Breast Neoplasms/pathology , Carcinoma, Lobular/secondary , Eye Neoplasms/secondary , Muscle Neoplasms/secondary , Oculomotor Muscles , Biopsy , Breast Neoplasms/therapy , Carcinoma, Lobular/diagnosis , Carcinoma, Lobular/therapy , Combined Modality Therapy , Diagnosis, Differential , Eye Neoplasms/diagnosis , Eye Neoplasms/therapy , Female , Follow-Up Studies , Humans , Magnetic Resonance Imaging , Middle Aged , Muscle Neoplasms/diagnosis , Muscle Neoplasms/therapy , Neoplasm Staging , Time FactorsABSTRACT
Cyclic exotropia, a very rare condition, consists of periods of exotropia and orthotropia alternating on a regular, most commonly 48-hour, cycle. Cyclic vertical deviations, including cyclic oculomotor nerve palsy, also are extremely uncommon. Cyclic esotropia, which is more common than cyclic exotropia, has been reported to occur more frequently in children than adults. We describe an adult patient who developed cyclic exotropia and hypotropia associated with monocular loss of vision.
