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1.
Article in German | MEDLINE | ID: mdl-21887619

ABSTRACT

The dental curriculum in Germany is still based on a concept from 1955 with some revisions in certain aspects. All groups involved are interested in a new and more current version. In doing this, the compatibility with European concepts should be a main goal. The Association for Dental Education in Europe (ADEE), to which about 160 of the 200 European dental education associations are members, is in charge of coordinating projects to create a network of European universities, which intends to harmonize higher education in Europe and to create a core curriculum for the dentistry program. Based on a visitation and evaluation program at more than 50 oral and maxillofacial surgery centers, a paper for the profiles and competencies for future European dentists was formulated for the creation of a modular curriculum, for the integration of the ECT (European Credit Transfer) system, and for quality assurance of the dentistry curriculum. Especially for the situation in Germany, consequences must be drawn for further dentistry and postgraduate educational concepts, which are not completely identical with the ADEE concepts, but which can use elements of the basic Bologna concepts.


Subject(s)
Education, Dental, Graduate/organization & administration , Education, Dental/organization & administration , European Union , National Health Programs , Curriculum/standards , Education, Dental/standards , Education, Dental, Continuing/organization & administration , Education, Dental, Continuing/standards , Education, Dental, Graduate/standards , Germany , Humans , Licensure, Dental/standards , Quality Assurance, Health Care/organization & administration , Quality Assurance, Health Care/standards , Schools, Dental/standards , Surgery, Oral/education , Surgery, Oral/standards
4.
Eur J Dent Educ ; 7(1): 41-8, 2003 Feb.
Article in English | MEDLINE | ID: mdl-12542688

ABSTRACT

This article reports the findings of a study on the aspects of the teaching of repair as a conservative alternative to the replacement of failing direct composite restorations (DCRs) in primary dental degree curricula in the UK and Ireland, Germany and Scandinavia. Data on teaching, including operative techniques applied in the repair of DCRs, were collected by means of a questionnaire sent to 58 dental schools in the surveyed countries. Based on the overall response rate of 83%, the findings indicate that the majority (59%) of the schools in the countries surveyed may be found to teach the repair of DCRs. However, marked variations were observed in respect of this teaching and the expected longevity of repaired DCRs. Where the repair of DCRs was not taught, views differed as to the intentions, if any, to include this teaching in the curriculum. It is concluded that the teaching of DCRs may be found to be widespread in dental schools in the UK and Ireland, Germany and Scandinavia, with this teaching being subjected to considerable variation within and between countries.


Subject(s)
Composite Resins , Curriculum , Dental Restoration, Permanent/methods , Dentistry, Operative/education , Education, Dental/methods , Dental Restoration Failure , Germany , Humans , Ireland , Retreatment , Scandinavian and Nordic Countries , Surveys and Questionnaires , United Kingdom
5.
Oper Dent ; 27(6): 613-20, 2002.
Article in English | MEDLINE | ID: mdl-12413228

ABSTRACT

This study investigated changes in the dimensions of Class II cavities following the removal of amalgam, glass ionomer and compomer restorations. In 30 extracted caries-free human molars, preparation for 60 mesio-occlusal and occluso-distal cavities (two cavities per tooth) occurred. With a CEREC 3 laser triangulation sensor and software-based construction analysis, the dimensions of the cavities at seven defined sites were measured. The cavities were randomized into four groups. Group 1 was restored with Ketac-Fil glass-ionomer cement, Group 2 with amalgam and Group 3 with Compoglass F compomer. In Group 4, Compoglass F was used in combination with photochromic Tetric Flow Chroma as a cavity liner. The completed restorations were then removed using 2x magnification and the cavities were once again controlled using the laser system. The duration of the removal procedure was also recorded. Changes in cavity dimensions (depth, height and width) following removal of the restorations were significantly smaller in Groups 1 and 2. Groups 3 and 4 were characterized by a significant overextension of the cavities compared to Groups 1 and 2 in all three dimensions. Group 4, with Tetric Flow Chroma as a cavity liner, showed better results than Group 3, but this improvement was not statistically significant. The duration of the removal procedure was significantly shorter in Group 2 than in the other groups.


Subject(s)
Compomers , Dental Amalgam , Dental Cavity Preparation , Dental Restoration, Permanent/methods , Glass Ionomer Cements , Composite Resins , Dental Cavity Lining , Humans , Lasers , Maleates , Molar , Retreatment
6.
Int Endod J ; 35(6): 557-72, 2002 Jun.
Article in English | MEDLINE | ID: mdl-12190914

ABSTRACT

AIM: To emphasize the importance of primary endodontic treatment when dealing with endo-perio lesions and to demonstrate the considerable healing potential of the endodontic aspect. CASE REPORT: After several years of unsuccessful symptomatic periodontal treatment, an advanced endo-perio lesion on a right-mandibular first molar was successfully treated by root-canal treatment and hemisection after the re-evaluation of the lesion. This successful treatment appeared to have a positive effect on the patient's general well-being. KEY LEARNING POINTS: The origin of a combined endo-perio lesion is indicated by its clinical and radiographic appearance. The periodontal situation is often misinterpreted. The prognosis for the endodontic element of treatment is excellent. Local pathologic processes in the oral cavity may affect a patient's general health.


Subject(s)
Periapical Periodontitis/surgery , Tooth Root/surgery , Female , Headache/etiology , Humans , Middle Aged , Periapical Periodontitis/complications , Root Canal Therapy , Tooth Crown/surgery
7.
Am J Ophthalmol ; 132(6): 819-30, 2001 Dec.
Article in English | MEDLINE | ID: mdl-11730644

ABSTRACT

PURPOSE: To describe a cluster of Mycobacterium chelonae keratitis cases involving patients who underwent laser in-situ keratomileusis (LASIK) at a single refractive surgery center. DESIGN: Descriptive case series of four patients and cohort study to identify disease associations. METHODS: Examination schedules, diagnostic tests, and therapy were based on best medical judgment. Isolates from three patients were compared by pulsed-field gel electrophoresis. Epidemiologic studies were performed to identify the source of infection. RESULTS: Seven of eight eyes developed M. chelonae keratitis following bilateral simultaneous LASIK. Each patient was thought to have diffuse lamellar keratitis initially, but all seven eyes were noted to have opacities suggestive of infectious keratitis by 13 to 21 days after surgery. All eyes had undergone hyperopic LASIK over four days in April 2001 by one surgeon in a community-based refractive surgery center. A cohort study of all patients undergoing LASIK at the same center in April 2001 revealed that M. chelonae keratitis occurred only in persons undergoing correction of hyperopia (seven of 14 eyes vs. none of 217 eyes undergoing myopic LASIK, P <.001). The only difference identified between procedures was use of masks created from a soft contact lens in hyperopic LASIK. Three isolates (three patients) were indistinguishable by pulsed-field gel electrophoresis. Eyes were treated with a combination of antimicrobial agents, including topical azithromycin in three patients, with resolution of infection in all eyes over 6 to 14 weeks. The source of infection was not identified on environmental cultures. CONCLUSION: Postoperative nontuberculous mycobacterial keratitis can occur in an epidemic fashion following LASIK. Topical amikacin, azithromycin, clarithromycin, ciprofloxacin, or a combination of these agents, appears to be effective treatment for these infections.


Subject(s)
Eye Infections, Bacterial/etiology , Keratitis/etiology , Keratomileusis, Laser In Situ/adverse effects , Mycobacterium Infections, Nontuberculous/etiology , Mycobacterium chelonae/isolation & purification , Anti-Bacterial Agents , Bacterial Proteins/analysis , California , Cluster Analysis , Cohort Studies , Cornea/microbiology , Cornea/surgery , Drug Therapy, Combination/therapeutic use , Electrophoresis, Gel, Pulsed-Field , Eye Infections, Bacterial/drug therapy , Eye Infections, Bacterial/epidemiology , Eye Infections, Bacterial/microbiology , Female , Humans , Hyperopia/surgery , Keratitis/drug therapy , Keratitis/epidemiology , Keratitis/microbiology , Middle Aged , Mycobacterium Infections, Nontuberculous/drug therapy , Mycobacterium Infections, Nontuberculous/epidemiology , Mycobacterium Infections, Nontuberculous/microbiology
9.
J Adhes Dent ; 3(2): 169-75, 2001.
Article in English | MEDLINE | ID: mdl-11570685

ABSTRACT

PURPOSE: To clinically measure the influence of rubber-dam on the proximal contact strength after its reconstruction with tooth-colored restorations. MATERIALS AND METHODS: The frictional forces during the removal of a metal strip from the proximal contact area were taken as measure for the proximal contact strengths of 46 restorations (35 ceramic inlays, 11 direct composite restorations). The teeth were separated with a rubber-dam and wedged thoroughly during the complete reconstruction procedure according to the multiple wedging technique. The proximal contact strengths were measured immediately before and immediately after removing the rubber-dam. RESULTS: The contact strengths were statistically significantly lower immediately after the removal of the rubber-dam (1.07+/-0.82N) compared to the situation with the rubber-dam (1.99+/-1.21N). The amount of the reduction after removing the rubber-dam was statistically significantly higher between the second premolar and the first molar (1.45+/-1.06N) compared to the contacts between the canines and the first premolar (0.32+/-0.44N) and the first and second premolar (0.59+/-0.77N). No influence of the restorative material, the use and localization of retainers, localization of the restoration, or number of teeth under the rubber-dam was detectable. CONCLUSION: Rubber-dam is recommended for adhesive restorations as it is helpful for achieving good adhesion between the tooth and restorative materials. Nevertheless, the application of rubber-dam seems to be a factor which complicates the reconstruction of adequate proximal contacts.


Subject(s)
Ceramics/chemistry , Composite Resins/chemistry , Dental Bonding , Dental Restoration, Permanent/methods , Rubber Dams , Analysis of Variance , Bicuspid/anatomy & histology , Cuspid/anatomy & histology , Dental Cavity Preparation/instrumentation , Dental Cavity Preparation/methods , Dental Restoration, Permanent/instrumentation , Friction , Humans , Inlays , Matrix Bands , Molar/anatomy & histology , Regression Analysis , Signal Processing, Computer-Assisted , Statistics as Topic , Stress, Mechanical , Surface Properties
10.
Clin Oral Investig ; 5(1): 17-25, 2001 Mar.
Article in English | MEDLINE | ID: mdl-11355093

ABSTRACT

This in vitro study evaluated the efficacy and safety of six different nickel-titanium engine-driven instruments used with a torque-controlled engine device and nickel-titanium hand and stainless steel hand instruments in preparation of curved canals. A total of 80 curved (36 degrees) simulated root canals were prepared. Images before and after were superimposed, and instrumentation areas were observed. Time of instrumentation, instrument failure, change in working length and weight loss were also recorded. Results show that stainless steel hand instruments cause significantly less transportation towards the inner wall of the canal than do nickel-titanium hand instruments. No instrument fracture occurred with hand instruments, but 30-60% breakage of instruments was recorded during instrumentation with the engine-driven devices. The working length was maintained by all types of instruments. Newly developed nickel-titanium rotary files were not able to prevent straightening of the severely curved canals when a torque-controlled engine-driven device was used.


Subject(s)
Dental Pulp Cavity/anatomy & histology , Root Canal Preparation/instrumentation , Dental Alloys , Equipment Design , Equipment Failure , Equipment Safety , Humans , Models, Anatomic , Nickel , Pulpectomy/instrumentation , Pulpectomy/methods , Root Canal Preparation/methods , Stainless Steel , Surface Properties , Time Factors , Titanium , Torque
11.
Pract Proced Aesthet Dent ; 13(3): 243-50; quiz 252, 2001 Apr.
Article in English | MEDLINE | ID: mdl-11360771

ABSTRACT

An in vitro study was performed to evaluate the effect of two different proximal restoration techniques with different matrix systems on the marginal seal and microhardness of Class II composite restorations. Results indicated that the lowest, however, not significantly different, microleakage was achieved in totally bonded deep Class II restorations prepared with margins surrounded by enamel when using transparent matrices and reflective wedges in combination with the centripetal buildup technique. Highest surface hardness of composite resin was related to transparent matrices and reflecting wedges.


Subject(s)
Composite Resins/chemistry , Dental Restoration, Permanent/methods , Coloring Agents , Dental Bonding , Dental Cavity Preparation/classification , Dental Cavity Preparation/instrumentation , Dental Cavity Preparation/methods , Dental Enamel/pathology , Dental Leakage/classification , Dental Marginal Adaptation , Dental Restoration, Permanent/classification , Dental Restoration, Permanent/instrumentation , Equipment Design , Hardness , Humans , Matrix Bands , Molar , Statistics, Nonparametric , Surface Properties
12.
J Prosthet Dent ; 83(6): 668-74, 2000 Jun.
Article in English | MEDLINE | ID: mdl-10842137

ABSTRACT

STATEMENT OF PROBLEM: Fracture of porcelain is a relatively common clinical misfortune. Recent research has indicated that strong bonds can be formed between composite and dental porcelain. Porcelain surfaces are etched with hydrofluoric acid and treated with silane coupling agents before composite application. The question is how exposed dentin may react to etching with hydrofluoric acid. PURPOSE: This investigation examined the effect of 9.5% buffered hydrofluoric acid, of 36% o-phosphoric acid alone and in combination on the surface structure of cut human dentin. MATERIAL AND METHODS: Human molar teeth were sectioned in approximately 0.8-mm thick slices and treated with different acids or their combinations. Application periods were 10, 60, and 180 seconds. Specimens were processed for SEM and for energy-dispersive x-ray (EDX) microanalysis. RESULTS: The smear layer on the surface of sectioned dentin was not completely removed by hydrofluoric acid alone and that a dense amorphous precipitate was formed on the peritubular zone. Starlike structures in dentinal tubules were visible. EDX analysis revealed different fluoride content on the treated surface, dependent on the etchant used. CONCLUSION: Topical application of hydrofluoric acid appeared to provide a dentinal surface with an amorphous precipitate of fluoride. This layer may be important both for resistance of dental caries in dentin and for bonding reactions.


Subject(s)
Acid Etching, Dental , Dental Porcelain/chemistry , Dentin/drug effects , Hydrofluoric Acid/pharmacology , Buffers , Dentin/ultrastructure , Electron Probe Microanalysis , Humans , In Vitro Techniques , Microscopy, Electron, Scanning , Phosphoric Acids/pharmacology , Smear Layer , Surface Properties , Time Factors
14.
J Cataract Refract Surg ; 26(1): 140-1, 2000 Jan.
Article in English | MEDLINE | ID: mdl-10646160

ABSTRACT

A 48-year-old man had simultaneous bilateral photorefractive keratectomy (PRK). The surgeon who performed the PRK did not see the patient in follow-up, and there was confusion regarding the comanaging doctor. Therefore, the patient was not examined immediately postoperatively. Several days later, he was hospitalized for an unrelated, painful orthopedic problem and heavily sedated. Seven days after the PRK, an ophthalmologist was consulted for ocular irritation and discharge. Examination showed bilateral, purulent conjunctivitis and severe infectious keratitis in the left eye. The patient was treated with periocular and topical antibiotics. Corneal cultures yielded Staphylococcus aureus. The keratitis resolved slowly, leaving the patient with hand motion visual acuity. A corneal transplant and cataract extraction was performed 15 months later, resulting in a best corrected visual acuity of 20/400 because of glaucomatous optic nerve damage. Severe infectious keratitis may occur after PRK. Poor communication between the surgeon, comanaging doctor, and patient may result in treatment delay.


Subject(s)
Corneal Ulcer/microbiology , Eye Infections, Bacterial , Photorefractive Keratectomy/adverse effects , Staphylococcal Infections , Staphylococcus aureus/isolation & purification , Surgical Wound Infection/microbiology , Anti-Bacterial Agents , Cataract Extraction , Conjunctivitis, Bacterial/microbiology , Conjunctivitis, Bacterial/pathology , Conjunctivitis, Bacterial/therapy , Cornea/microbiology , Cornea/pathology , Cornea/surgery , Corneal Transplantation , Corneal Ulcer/pathology , Corneal Ulcer/therapy , Drug Therapy, Combination/administration & dosage , Eye Infections, Bacterial/microbiology , Eye Infections, Bacterial/pathology , Eye Infections, Bacterial/therapy , Humans , Lasers, Excimer , Male , Middle Aged , Ophthalmic Solutions , Staphylococcal Infections/microbiology , Staphylococcal Infections/pathology , Staphylococcal Infections/therapy , Surgical Wound Infection/pathology , Surgical Wound Infection/therapy , Visual Acuity
15.
J Cataract Refract Surg ; 25(12): 1615-9, 1999 Dec.
Article in English | MEDLINE | ID: mdl-10609205

ABSTRACT

PURPOSE: To compare the clinical characteristics of early- versus late-onset keratitis after radial keratotomy (RK) and astigmatic keratotomy (AK). SETTING: Referral subspecialty practice. METHODS: This retrospective review comprised 19 patients with infectious keratitis after RK and AK. Early- versus late-onset groups were analyzed for predisposing conditions; infiltrate location, size, and depth; microbiologic data; and final visual outcome. RESULTS: Ten patients in the early-onset group developed keratitis within a mean of 7.4 days after surgery (range 3 to 14 days). Nine patients in the late-onset group developed keratitis a mean of 5.4 years after surgery (range 1.5 to 15.0 years). Staphylococcus aureus was the predominant organism in the early-onset group and Pseudomonas aeruginosa in the late-onset group. In the early-onset group, most infiltrates occurred in the paracentral aspect of the RK incision and extended to the middle or posterior stroma. In the late-onset group, most infiltrates occurred in the peripheral portion of the RK incision and were localized to the superficial stroma. A hypopyon was present in 7 of 10 ulcers in the early group and in 1 of 9 in the late group. Two patients in the early group developed endophthalmitis. Most patients in the late-onset group had incisional pseudocysts; 2 had other risk factors for keratitis. Final visual acuity was 20/40 or better in 7 of 10 patients in the early group and in 8 of 9 patients in the late group. CONCLUSIONS: Early-onset corneal ulcers after incisional refractive keratotomy were usually paracentral and deep, whereas late-onset ulcers were usually peripheral and superficial. Despite the predominance of Staphylococcus and Pseudomonas in the early- and late-onset groups, respectively, a variety of organisms may be responsible for infections in keratotomy incisions.


Subject(s)
Astigmatism/surgery , Corneal Ulcer/microbiology , Eye Infections, Bacterial , Keratotomy, Radial/adverse effects , Pseudomonas Infections , Staphylococcal Infections , Adult , Aged , Cornea/microbiology , Cornea/pathology , Cornea/surgery , Corneal Ulcer/pathology , Eye Infections, Bacterial/etiology , Eye Infections, Bacterial/pathology , Humans , Middle Aged , Pseudomonas Infections/etiology , Pseudomonas Infections/pathology , Pseudomonas aeruginosa/isolation & purification , Referral and Consultation , Retrospective Studies , Staphylococcal Infections/etiology , Staphylococcal Infections/pathology , Staphylococcus aureus/isolation & purification , Visual Acuity
16.
Clin Oral Investig ; 3(1): 30-4, 1999 Mar.
Article in English | MEDLINE | ID: mdl-10522190

ABSTRACT

Optimizing the quality of tooth-colored restorations is one of the main topics of current research. But there is only little information available about university education in this field. The aim of this study was to collect and evaluate data about the different aspects of dental education in Germany concerning tooth-colored restorations. Based on the response to a questionnaire from 90% of all German dental schools in the fall of 1997 a detailed survey is given of the utilization, indications, practical procedure, problems and limitations of both direct and indirect tooth-colored restorations done by students. The results indicate a wide-spread use of directly inserted composite for posterior teeth in the different education programs. Indeed, the preferred preparation of the cavity margin differs from school to school. Rebuilding an adequate proximal contact and a precise fit at the gingival margin are looked upon as the main problems of class II composite fillings. Ceramic inlays are mainly inserted by students in advanced clinical courses with the insertion procedure being claimed as the main problem of this technique. The findings of this study mostly show the same limitations and difficulties of tooth-colored restorations in education as found by research. Partly different teaching concepts are reflected in the differing scientific results.


Subject(s)
Dental Restoration, Permanent/methods , Dentistry, Operative/education , Education, Dental , Prosthesis Coloring , Composite Resins , Dental Cavity Preparation/methods , Dental Porcelain , Germany , Humans , Molar , Surveys and Questionnaires
18.
J Dent ; 26(8): 649-56, 1998 Nov.
Article in English | MEDLINE | ID: mdl-9793286

ABSTRACT

OBJECTIVES: In previous studies it has been demonstrated that the Er:YAG laser can be used to prepare cavities efficiently and without thermal damage to the adjacent dental hard and soft tissues. To investigate the patients' response to Er:YAG laser preparation of teeth, a prospective clinical study was performed in five dental hospitals. METHODS: To evaluate patients' perception and response to cavity preparation a direct comparison was made between conventional mechanical preparation and Er:YAG laser preparation of caries in dental hard tissues. Half of the preparations were completed by the laser alone with standardized parameters, with the other half being mechanically prepared. The sequential order of treatment was randomized, and clinical parameters such as depth and location of the cavities were carefully balanced. A three-score evaluation scheme of patient responses was used: comfortable, uncomfortable, very uncomfortable. In addition the patients were asked to decide which was the more uncomfortable form of treatment and the preferred treatment for future caries therapy. RESULTS: The study included 103 patients with 206 preparations distributed amongst 194 teeth. All teeth gave vital responses (ice test) before and after both types of treatment. The laser treatment was found to be more comfortable than the mechanical treatment, with high statistical significance. During treatment, the need for local anaesthesia was 11% for mechanical preparation compared to 6% during laser application. It was found that 80% of the patients rated the conventional preparation as more uncomfortable than the laser treatment and 82% of the patients indicated that they would prefer the Er:YAG laser preparation for further caries treatment. CONCLUSIONS: The application of the Er:YAG laser system is a more comfortable alternative or adjunctive method to conventional mechanical cavity preparation.


Subject(s)
Dental Cavity Preparation/instrumentation , Laser Therapy , Adult , Dental Caries/therapy , Dental Cavity Preparation/psychology , Erbium , Humans , Pain Measurement , Patient Acceptance of Health Care , Patient Satisfaction , Time Factors
19.
J Cataract Refract Surg ; 23(6): 951-3, 1997.
Article in English | MEDLINE | ID: mdl-9292684

ABSTRACT

A 45-year-old man developed endophthalmitis after a radial keratotomy (RK) enhancement. He developed severe intraocular inflammation, hypopyon, and dense vitreous membranes 4 days after the enhancement surgery. Cultures of the corneal wound yielded a heavy growth of Streptococcus viridans. The inflammation subsided after treatment with intraocular, intravenous, and topical antibiotics. The patient subsequently developed a cataract and retinal detachment. This case demonstrates the risk of endophthalmitis after RK enhancement.


Subject(s)
Endophthalmitis/microbiology , Eye Infections, Bacterial/etiology , Keratotomy, Radial/adverse effects , Streptococcal Infections/etiology , Anterior Chamber/microbiology , Anterior Chamber/pathology , Anterior Chamber/surgery , Anti-Bacterial Agents , Astigmatism/surgery , Cataract/etiology , Drug Administration Routes , Drug Therapy, Combination/administration & dosage , Drug Therapy, Combination/therapeutic use , Endophthalmitis/drug therapy , Endophthalmitis/pathology , Eye Infections, Bacterial/drug therapy , Eye Infections, Bacterial/pathology , Humans , Male , Middle Aged , Retinal Detachment/etiology , Streptococcal Infections/drug therapy , Streptococcal Infections/pathology , Streptococcus/isolation & purification , Surgical Wound Infection/drug therapy , Surgical Wound Infection/etiology , Surgical Wound Infection/pathology
20.
Am J Ophthalmol ; 120(2): 254-6, 1995 Aug.
Article in English | MEDLINE | ID: mdl-7639314

ABSTRACT

PURPOSE/METHODS: A case of severe Aspergillus keratitis after radial keratotomy manifested as a discrete midstromal infiltrate along a radial incision. Despite aggressive treatment with topical amphotericin B and oral itraconazole, the patient required a therapeutic penetrating keratoplasty. RESULTS/CONCLUSIONS: Histopathologic examination disclosed a corneal ulcer with numerous septate, branching hyphae throughout the stroma, and marked stromal necrosis. Aspergillus species should be included among the microbial pathogens responsible for infectious keratitis after radial keratotomy. If infectious keratitis is suspected, comprehensive cultures for bacteria and fungi should be obtained.


Subject(s)
Aspergillosis/etiology , Aspergillus fumigatus/isolation & purification , Corneal Ulcer/microbiology , Eye Infections, Fungal/etiology , Keratotomy, Radial/adverse effects , Amphotericin B/therapeutic use , Aspergillosis/pathology , Aspergillosis/therapy , Cornea/microbiology , Cornea/pathology , Corneal Ulcer/pathology , Corneal Ulcer/therapy , Eye Infections, Fungal/pathology , Eye Infections, Fungal/therapy , Female , Humans , Itraconazole/therapeutic use , Keratoplasty, Penetrating , Microbial Sensitivity Tests , Middle Aged
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