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IEEE/ACM Trans Comput Biol Bioinform ; 17(6): 1895-1906, 2020.
Article in English | MEDLINE | ID: mdl-30869629

ABSTRACT

We present an analysis of the problem of identifying biological context and associating it with biochemical events described in biomedical texts. This constitutes a non-trivial, inter-sentential relation extraction task. We focus on biological context as descriptions of the species, tissue type, and cell type that are associated with biochemical events. We present a new corpus of open access biomedical texts that have been annotated by biology subject matter experts to highlight context-event relations. Using this corpus, we evaluate several classifiers for context-event association along with a detailed analysis of the impact of a variety of linguistic features on classifier performance. We find that gradient tree boosting performs by far the best, achieving an F1 of 0.865 in a cross-validation study.


Subject(s)
Computational Biology/methods , Data Mining/methods , Natural Language Processing , Animals , Biomedical Research , Databases, Factual , Humans , Mice
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