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1.
Pediatr Clin North Am ; 48(1): 105-23, ix, 2001 Feb.
Article in English | MEDLINE | ID: mdl-11236719

ABSTRACT

Breastfeeding confers lifesaving protection against infectious illness among disadvantaged populations. As a result, breastfeeding promotion has an important part in child health programs throughout the world. In this article, the evidence regarding the host defense benefits of breastfeeding for term infants of normal birth weight is reviewed, with an emphasis on recent information from industrialized countries regarding how the degree and duration of breastfeeding affect infant health.


Subject(s)
Breast Feeding , Milk, Human/physiology , Gastrointestinal Diseases/epidemiology , Gastrointestinal Diseases/prevention & control , Humans , Infant , Milk, Human/immunology , Otitis Media/epidemiology , Otitis Media/prevention & control , Respiratory Tract Diseases/epidemiology , Respiratory Tract Diseases/prevention & control , Time Factors
3.
J Hum Lact ; 17(1): 5-6, 2001 Feb.
Article in English | MEDLINE | ID: mdl-11847852
6.
J Trauma ; 48(4): 673-82; discussion 682-3, 2000 Apr.
Article in English | MEDLINE | ID: mdl-10780601

ABSTRACT

BACKGROUND: Thoracic aortic injury (TAI) is a devastating condition in which prompt recognition can obviate morbidity and mortality. It is a long-held belief that TAI is more likely when there is a "major mechanism of injury." The purposes of this prospective study were to determine mechanism characteristics that are predictive of TAI and to evaluate chest computed tomography (CT) as a screening tool for TAI. METHODS: Over a 5 1/2 year period, blunt chest trauma patients at two Level I trauma centers were evaluated for potential TAI. Patients were assigned mechanism and radiograph scores from 1 (low suspicion for TAI) to 5 (very high suspicion for TAI). Immediate aortography was obtained when suspicion for TAI was very high. The remaining patients were evaluated with contrast-enhanced chest CT. Confirmatory aortography was obtained on all positive chest CT scans and on all patients with mechanism scores of 4 or 5 even if the CT was negative. Mechanism and radiographic data were correlated with the results of aortic imaging. RESULTS: Of the 1,561 patients evaluated for TAI, 30 aortic injuries were found. The assessment of mechanism was imperfect with a reliance on often incomplete and subjective data. The subjective mechanism score proved to be the most useful predictor of TAI. Radiographic scores were useful but insensitive for intimal injuries. Computed tomography was found to have 100% and 100% NPV for TAI. CONCLUSION: Considering the inherent difficulties in identifying patients at risk for TAI and the effectiveness of chest CT as a screening tool for aortic injury, we recommend liberal use of chest CT in blunt chest trauma. Guidelines for determining the need for aortic imaging are outlined.


Subject(s)
Aorta, Thoracic/diagnostic imaging , Aorta, Thoracic/injuries , Tomography, X-Ray Computed , Wounds, Nonpenetrating/diagnostic imaging , Wounds, Nonpenetrating/etiology , Accidental Falls , Accidents, Traffic , Aortography , Female , Humans , Male , Prospective Studies , Radiography, Thoracic
12.
Radiology ; 213(1): 195-202, 1999 Oct.
Article in English | MEDLINE | ID: mdl-10540662

ABSTRACT

PURPOSE: To determine whether chest computed tomography (CT) can be used to exclude aortic injury. MATERIALS AND METHODS: Patients in whom there was very high suspicion of traumatic aortic injury were examined with aortography only. Other patients were examined with contrast material-enhanced CT. Follow-up aortography was performed in all patients with moderate to high suspicion of traumatic aortic injury and in all patients with CT scans that were positive for traumatic aortic injury. CT scans were regarded as positive when they showed mediastinal hematoma or direct findings of aortic injury. During a 4 1/2-year period, 1,009 patients (263 female, 746 male; age range, 3-90 years) were evaluated for possible traumatic aortic injury. RESULTS: Of the 207 patients who underwent aortography directly without CT, 10 had traumatic aortic injury. Of the 802 patients who were examined with CT, 382 underwent follow-up aortography. In this group, there were 10 true-positive and no false-negative CT scans. CT had 100% sensitivity and a 100% negative predictive value for the detection of traumatic aortic injury.


Subject(s)
Aorta/injuries , Aortography , Radiography, Thoracic , Tomography, X-Ray Computed , Adolescent , Adult , Aged , Aged, 80 and over , Aortography/economics , Child , Child, Preschool , Contrast Media , Costs and Cost Analysis , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Radiography, Thoracic/economics , Sensitivity and Specificity , Tomography, X-Ray Computed/economics
14.
J Hum Lact ; 15(4): 281-8, 1999 Dec.
Article in English | MEDLINE | ID: mdl-10776178

ABSTRACT

Though perceived to be a growing problem by lactation professionals, fungal infection of the breast (mammary candidosis) is largely unstudied. Candida albicans, a commensal organism encountered frequently in the vagina and gastrointestinal tract of humans, has been reported to be responsible for both superficial (cutaneous) and localized (ductal) infection of the mammary gland in lactating women, though the latter association is not universally accepted. Severe pain is considered to be characteristic of yeast infection of the breast and may be a cause of premature weaning among lactating mothers. Given that pain is often the complaint that prompts mothers to consult lactation professionals, it is important that healthcare providers working with lactating women be knowledgeable about this disease. In this article, current research regarding yeast infection of the breast is summarized, including morphology and pathology, diagnosis, risk factors, and common treatment options.


Subject(s)
Breast Diseases , Breast Feeding , Candidiasis, Cutaneous , Antifungal Agents/therapeutic use , Breast Diseases/diagnosis , Breast Diseases/etiology , Breast Diseases/therapy , Candidiasis, Cutaneous/diagnosis , Candidiasis, Cutaneous/etiology , Candidiasis, Cutaneous/therapy , Consultants , Female , Humans , Pain/microbiology , Risk Factors , Skin Care/methods
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