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South Med J ; 91(3): 289-92, 1998 Mar.
Article in English | MEDLINE | ID: mdl-9521375

ABSTRACT

Merkel's cell carcinoma is an uncommon neuroendocrine cutaneous neoplasm. An unusual mode of dissemination of this tumor is the phenomenon of in-transit metastases. We report complete resolution of in-transit metastases from a Merkel's cell carcinoma in response to treatment with isolated hyperthermic limb perfusion with melphalan. Limb perfusion appears to be a promising modality for such lesions.


Subject(s)
Antineoplastic Agents, Alkylating/administration & dosage , Carcinoma, Merkel Cell/drug therapy , Carcinoma, Merkel Cell/pathology , Chemotherapy, Cancer, Regional Perfusion/methods , Hyperthermia, Induced/methods , Melphalan/administration & dosage , Skin Neoplasms/drug therapy , Skin Neoplasms/pathology , Aged , Humans , Lymphatic Metastasis , Male
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