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Vet Comp Oncol ; 16(1): 140-147, 2018 Mar.
Article in English | MEDLINE | ID: mdl-28524617

ABSTRACT

The accurate evaluation of sternal lymph nodes (StLNs) is critical for the staging of canine thoraco-abdominal tumours. Computed tomography (CT) provides a non-invasive means of assessing StLNs, but its diagnostic accuracy for identifying metastases is unclear. In this retrospective cross-sectional study, we assessed the diagnostic power of various CT measurements. Fifty-seven dogs that underwent concurrent CT and cytological examination of the StLNs were enrolled retrospectively. The size, shape, X-ray attenuation and uniformity of the StLNs were assessed. The dogs were divided into metastasis-negative (n = 21) and metastasis-positive (n = 36) groups. Logistic regression analysis showed that the size (StLN-to-second sternebra ratio [ratio-size]) and precontrast attenuation were significantly different between groups. Combining these parameters achieved a specificity and positive predictive value of 100% (cut-off values: 1.0, 37.5 Hounsfield units, respectively). This suggests that the combination of ratio-size and precontrast attenuation is effective for differentiating metastasis to the StLNs on CT.


Subject(s)
Dog Diseases/diagnostic imaging , Lymph Nodes/diagnostic imaging , Lymphatic Metastasis/diagnostic imaging , Tomography, X-Ray Computed/veterinary , Animals , Cross-Sectional Studies , Dog Diseases/diagnosis , Dog Diseases/pathology , Dogs , Female , Lymph Nodes/pathology , Lymphatic Metastasis/diagnosis , Male , Retrospective Studies , Sternum
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