1.
Org Biomol Chem
; 13(46): 11208-19, 2015 Dec 14.
Article
in English
| MEDLINE
| ID: mdl-26381107
ABSTRACT
d-Glucosamine derivatives bearing latent O4 functionality provide modified H/HS-type disaccharide donors for a final stage capping approach enabling introduction of conjugation-suitable, non-reducing terminal functionality to biologically important glycosaminoglycan oligosaccharides. Application to the synthesis of the first O4-terminus modified synthetic LMWH decasaccharide and an HS-like dodecasaccharide is reported.