ABSTRACT
Multisystem inflammatory syndrome in children (MIS-C) is a rare but severe post-infectious complication of SARSCoV- 2 that seems to occur most frequently two to six weeks after infection. MIS-C can present very similarly to Kawasaki's disease (KD) with symptoms such as a skin rash in addition to a prolonged fever. Here we present a case of a 12-year-old African American/Black female with incomplete KD presenting similarly to MIS-C. The patient presented with prolonged fever, eventually worsening to shock and cardiac dysfunction. We further review the similarities and differences between incomplete KD and MIS-C. Due to their similarities, it is important to keep these diagnoses on the differential when a child presents with a prolonged fever.
Subject(s)
COVID-19 , Mucocutaneous Lymph Node Syndrome , Systemic Inflammatory Response Syndrome , Humans , Female , Mucocutaneous Lymph Node Syndrome/diagnosis , Mucocutaneous Lymph Node Syndrome/complications , Child , Systemic Inflammatory Response Syndrome/diagnosis , Systemic Inflammatory Response Syndrome/etiology , COVID-19/complications , COVID-19/diagnosis , Diagnosis, DifferentialABSTRACT
Sotos syndrome is an uncommon congenital overgrowth syndrome characterized by excessive growth in childhood, learning disabilities, and distinct facial features. We present the case of a young male who appeared to have the classic presentation of Sotos syndrome despite a normal genetic workup. Additionally, we present a brief review of overgrowth syndromes in order to highlight potential challenges differentiating these syndromes in clinical practice. Many overgrowth disorders often have similar presentation to Sotos syndrome, so it is important to recognize and identify specific clinical features and perform genetic testing to rule out other disorders, confirm a diagnosis, and choose the appropriate management for patients.
Subject(s)
Sotos Syndrome , Humans , Male , Sotos Syndrome/diagnosis , Sotos Syndrome/genetics , Diagnosis, DifferentialABSTRACT
Inflammatory bowel disease is a term describing a group of diseases, Crohn's disease and ulcerative colitis, that cause chronic inflammation in the gastrointestinal tract. Both conditions tend to have episodic flares of diarrhea, abdominal pain, fatigue, and unintentional weight loss. This analysis will discuss the etiology, pathophysiology, epidemiology, clinical and histologic features, treatment, and complications of Crohn's disease and ulcerative colitis. Though there are many similarities between these two conditions it is important to recognize their differences for accurate diagnosis, treatment, and surveillance for potential long-term complications.
Subject(s)
Colitis, Ulcerative , Crohn Disease , Inflammatory Bowel Diseases , Humans , Abdominal Pain/diagnosis , Abdominal Pain/etiology , Colitis, Ulcerative/diagnosis , Colitis, Ulcerative/epidemiology , Colitis, Ulcerative/therapy , Diarrhea , Inflammatory Bowel Diseases/diagnosis , Inflammatory Bowel Diseases/epidemiology , Inflammatory Bowel Diseases/therapyABSTRACT
We report the case of a 19-year-old Native American woman who presented with bilateral lower extremity weakness due to spinal cord compression from late-stage Hodgkin's lymphoma. Hodgkin's lymphoma rarely has an initial presentation of spinal cord compression, except in cases of late-stage disease. The patient partially attributed her delayed pursuit of care to the difficulty of scheduling an appointment during the coronavirus (COVID-19) pandemic. The COVID-19 pandemic has impacted access to care and the potential for early detection of disease, as seen in this patient. Additionally, Native Americans on South Dakota Reservations face unique challenges that affect access to healthcare and health outcomes.
