ABSTRACT
Objectives. This work sought to identify the academic communities that have shown interest and participation in the Journal Research and Education in Nursing and analyze the scientific impact generated by said journal. Methods. A bibliometric analysis was carried out, as well as social network analysis and techniques of natural language processing to conduct the research. The data was gathered and analyzed during a specific study period, covering from 2010 - 2020, for articles published in the journal, and 2010 - 2022, for articles that cited the journal within Scopus. These methods permitted performing an exhaustive evaluation of the journal's influence and reach in diverse academic and geographic contexts. Results. During the analysis, it was noted that the journal Research and Education in Nursing has had significant influence in academic and scientific communities, both nationally and internationally. Collaboration networks were detected among diverse institutions and countries, which indicates active interaction in the field of nursing research. In addition, trends and emerging patterns were identified in this field, providing a more complete view of the discipline's evolution. Conclusion. Based on the results obtained, it is concluded that the journal Research and Education in Nursing has played un fundamental role in disseminating knowledge and promoting research in nursing. The combination of Bibliometric metrics, social network analysis, and natural language processing permitted utmost comprehension of its impact in the scientific and academic community globally.
Objetivos. Identificar las comunidades académicas que han mostrado interés y participación en la revista Investigación y Educación en Enfermería y analizar el impacto científico generado por esta publicación. Métodos. Se realizó un análisis bibliométrico, así como análisis de redes sociales y técnicas de procesamiento de lenguaje natural para llevar a cabo la investigación. Los datos se recopilaron y analizaron durante un período de estudio específico, abarcando los años 2010-2020, para los artículos publicados en la revista, y 2010-2022, para los artículos que citaron la revista dentro de Scopus. Estos métodos permitieron realizar una evaluación exhaustiva de la influencia y alcance de la revista en diversos contextos académicos y geográficos. Resultados. Durante el análisis, se observó que la revista Investigación y Educación en Enfermería ha ejercido una influencia significativa en las comunidades académicas y científicas, tanto a nivel nacional como internacional. Se detectaron redes de colaboración entre diversas instituciones y países, lo que indica una interacción activa en el ámbito de la investigación en enfermería. Además, se identificaron tendencias y patrones emergentes en este campo, proporcionando una visión más completa de la evolución de la disciplina. Conclusión. Basándose en los resultados obtenidos, se concluye que la revista Investigación y Educación en Enfermería ha desempeñado un papel fundamental en la difusión del conocimiento y la promoción de la investigación en enfermería. La combinación de métricas bibliométricas, análisis de redes sociales y procesamiento de lenguaje natural permitió una comprensión más completa de su impacto en la comunidad científica y académica a nivel global.
Objetivos. Identificar as comunidades acadêmicas que demonstraram interesse e participação na revista Nursing Research and Education e analisar o impacto científico gerado por esta publicação colombiana. Métodos. Foi realizada análise bibliométrica, análise de redes sociais e técnicas de processamento de linguagem natural para a realização da pesquisa. Os dados foram coletados e analisados durante um período específico de estudo, abrangendo os anos 2010-2020, para artigos publicados na revista, e 2010-2022, para artigos que citaram a revista dentro do Scopus. Esses métodos permitiram uma avaliação abrangente da influência e do alcance da revista em diversos contextos acadêmicos e geográficos. Resultados. Durante a análise, observou-se que a revista Nursing Research and Education tem exercido influência significativa nas comunidades acadêmica e científica, tanto nacional quanto internacionalmente. Foram detectadas redes de colaboração entre diversas instituições e países, o que indica interação ativa no campo da pesquisa em enfermagem. Além disso, foram identificadas tendências e padrões emergentes neste campo, proporcionando uma visão mais completa da evolução da disciplina. Conclusão. Com base nos resultados obtidos, conclui-se que a revista Nursing Research and Education tem desempenhado um papel fundamental na divulgação do conhecimento e na promoção da investigação em enfermagem. A combinação de métricas bibliométricas, análise de redes sociais e processamento de linguagem natural permitiu uma compreensão mais completa do seu impacto na comunidade científica e académica global.
Subject(s)
Humans , Male , Female , Research , Education , Social Network Analysis , Natural Language ProcessingABSTRACT
Objective: This work sought to identify the academic communities that have shown interest and participation in the Journal Research and Education in Nursing and analyze the scientific impact generated by said journal. Methods: A bibliometric analysis was carried out, as well as social network analysis and techniques of natural language processing to conduct the research. The data was gathered and analyzed during a specific study period, covering from 2010 - 2020, for articles published in the journal, and 2010 - 2022, for articles that cited the journal within Scopus. These methods permitted performing an exhaustive evaluation of the journal's influence and reach in diverse academic and geographic contexts. Results: During the analysis, it was noted that the journal Research and Education in Nursing has had significant influence in academic and scientific communities, both nationally and internationally. Collaboration networks were detected among diverse institutions and countries, which indicates active interaction in the field of nursing research. In addition, trends and emerging patterns were identified in this field, providing a more complete view of the discipline's evolution. Conclusion: Based on the results obtained, it is concluded that the journal Research and Education in Nursing has played un fundamental role in disseminating knowledge and promoting research in nursing. The combination of Bibliometric metrics, social network analysis, and natural language processing permitted utmost comprehension of its impact in the scientific and academic community globally.
Subject(s)
Bibliometrics , Natural Language Processing , Nursing Research , Periodicals as Topic , Humans , Periodicals as Topic/statistics & numerical data , Social Network Analysis , Education, NursingABSTRACT
RESUMEN Introducción: El trastorno por excoriación está incluido en el DSM - 5 dentro de la categoría Recibido el 4 de abril de 2017 de trastorno obsesivo compulsivo y trastornos relacionados. Se define como la urgencia Aceptado el 18 de marzo de 2018 de tocar, rascar, frotar, restregar, friccionar, apretar, morder o excavar la piel de forma On-line el 7 de mayo de 2018 recurrente hasta producirse lesiones cutáneas. Es un trastorno poco frecuente (1.4 - 5.4% de la población) y se presenta principalmente en mujeres. Presentación de caso: Se presenta el caso de una mujer de 31 años quien fue valorada por dermatología y ortopedia por presencia de lesiones ulceradas e infectadas en miembros inferiores, junto con otras lesiones superficiales por rascado en tórax, brazos, antebrazos, espalda y cabeza; además reportando síntomas ansiosos, razón por la cual es valorada por el servicio de Psiquiatría de enlace Discusión: El rascado cutáneo, conducta normal en los mamíferos, cobra valor patológico desde el punto de vista psiquiátrico al ser un acto repetitivo y persistente, como la conducta que se presenta en el trastorno por excoriación. Dada la relación descrita con el espectro obsesivo - compulsivo, se recomienda el uso de inhibidores selectivos de la recaptación de serotonina y la terapia cognitivo conductual.
ABSTRACT Introduction: Excoriation (skin picking) disorder is included in the DSM-5 in the obsessive compulsive and related disorders category. It is defined as the recurrent urge to touch, scratch, scrape, scrub, rub, squeeze, bite or dig in the skin, leading to skin lesions. It is a rare disorder (1.4-5.4% of the population) and occurs mainly in women. Case report: this article reports the case of a 31-year-old female patient, initially assessed by dermatology and orthopaedics for the presence of infected ulcerated lesions on her lower limbs, with other superficial lesions from scratching on her chest, arms, forearms, back and head. The patient also reported symptoms of anxiety, so was assessed by consultation-liaison psychiatry. Discussion: skin picking, normal behaviour in mammals, becomes pathological from a psychiatric point of view when it is repetitive and persistent, as in the case of excoriation disorder. In view of the reported relationship with the obsessive-compulsive spectrum, use of selective serotonin reuptake inhibitors and cognitive behavioural therapy are recommended.
Subject(s)
Humans , Female , Adult , Polyarteritis Nodosa , Obsessive-Compulsive Disorder , Anxiety , Psychiatry , Skin , Bites and Stings , Selective Serotonin Reuptake Inhibitors , ElapidaeABSTRACT
INTRODUCTION: Excoriation (skin picking) disorder is included in the DSM-5 in the obsessive compulsive and related disorders category. It is defined as the recurrent urge to touch, scratch, scrape, scrub, rub, squeeze, bite or dig in the skin, leading to skin lesions. It is a rare disorder (1.4-5.4% of the population) and occurs mainly in women. CASE REPORT: this article reports the case of a 31-year-old female patient, initially assessed by dermatology and orthopaedics for the presence of infected ulcerated lesions on her lower limbs, with other superficial lesions from scratching on her chest, arms, forearms, back and head. The patient also reported symptoms of anxiety, so was assessed by consultation-liaison psychiatry. DISCUSSION: skin picking, normal behaviour in mammals, becomes pathological from a psychiatric point of view when it is repetitive and persistent, as in the case of excoriation disorder. In view of the reported relationship with the obsessive-compulsive spectrum, use of selective serotonin reuptake inhibitors and cognitive behavioural therapy are recommended.
Subject(s)
Obsessive-Compulsive Disorder/diagnosis , Polyarteritis Nodosa/pathology , Self-Injurious Behavior/diagnosis , Skin Diseases/diagnosis , Adult , Anxiety/psychology , Female , Humans , Obsessive-Compulsive Disorder/pathology , Obsessive-Compulsive Disorder/therapy , Self-Injurious Behavior/pathology , Skin Diseases/pathology , Skin Diseases/therapyABSTRACT
Most evidence on breast cancer screening accuracy derives from high income countries. We evaluated screening accuracy and factors related to program implementation in Bogota, Colombia. Between 2008 and 2012 participants underwent clinical breast examination (CBE) and mammography. Positive results underwent histological verification. Adherence to screening protocols was analyzed. Sensitivity, specificity, and predictive values were estimated and adjusted by overdiagnosis. Impact of alternative screening algorithms on follow-up was explored, including combined screening tests and modified coding systems for mammography. In total, 7436 women aged 50-69 were enrolled; 400 discontinued and 1003 non-compliant with screening protocols. 23 cancer cases were diagnosed. Mammography sensitivity and specificity were 78.3% (95%CI 77.3-99.3) and 99.4% (95%CI 99.2-99.6). CBE sensitivity was 39.1% (95%CI 37.9-40.3) and specificity 83.4% (95%CI 82.6-84.3). Parallel mammography and CBE showed the highest sensitivity (95.6%) and combined as serial tests the lowest (positive CBE followed by mammography 13.0%). A simplified coding system for mammography (recall/no-recall) had 6.3% of positive results and a minor reduction in specificity compared with standard mammography, but reported the best balance between recall rates and screening protocol compliance. Call-backs had high rates of loss-to-follow-up; thus, alternative screening algorithms might help increase screening compliance and follow-up in low and middle income countries, particularly in populations with poor screening history and low access to health services.
Subject(s)
Breast Neoplasms/diagnosis , Early Detection of Cancer/methods , Mammography , Mass Screening/methods , Physical Examination/methods , Aged , Breast Neoplasms/pathology , Colombia , Female , Humans , Medical Overuse , Middle Aged , Sensitivity and SpecificityABSTRACT
Objetivos: identificar los estresores en las prácticas clínicas de los alumnos de la Facultad de Enfermería de una universidad pública de Antioquia (Colombia) y explorar la relación entre el grado de estrés y las variables sexo y semestre académico. Métodos: estudio cuantitativo de tipo transversal realizado durante el primer semestre académico de 2016. La población de estudio fueron todos los estudiantes de quinto a octavo semestres en práctica clínica. No se hizo muestreo. Los participantes contestaron por autorreporte la escala KEZKAK de Zupiría et al. que evalúa 41 estresores en las prácticas clínicas de los estudiantes de enfermería. Los puntajes mayores de 1,5 indican que hay estrés. Resultados: participaron 156 de los 224 estudiantes matriculados (69,6% del total). El promedio de la escala fue de 2,0, que equivale a un estrés moderado. En el 88% de los ítems mostraron algún grado de estrés (3 ítems con nivel alto > 2,5: hacer mal mi trabajo y perjudicar al paciente, hacer daño físico al paciente, y confundirme de medicación). Se presentaron diferencias estadísticamente significativas en el puntaje promedio total en las variables sexo (mayor en el femenino) y semestre académico (mayor en el quinto). Se encontró que los dominios del KESKAK con mayores puntajes fueron: falta de competencia (2,2), sobrecarga de trabajo (2,2), contacto con el sufrimiento (2,0) y que el paciente busque una relación íntima (2,0). Conclusión: los estudiantes de enfermería tienen un estrés moderado ocasionado por situaciones de la práctica clínica; predominan los factores relacionados con la falta de competencia y la sobrecarga de trabajo.
Objective: To identify the stressors in clinical practices in students from the Faculty of Nursing at a public university in Antioquia (Colombia) and to explore the relationship between stress level and the variables sex and academic semester. Methods: A cross-sectional, quantitative study was conducted during the first 2016 academic semester. The study population was all students from 5th to 8th semester in clinical practice, no sampling was done. The participants answered by self-report the KEZKAK scale by Zupiria et al. to evaluate 41 stressors in the clinical practices of nursing students. Scores above 1,5 indicated the presence of stress. Results: 156 of the 224 enrolled students participated in the study (69.6% of the total). The mean for the scale was 2,0, which is equivalent to moderate stress level; 88% of the items showed some degree of stress (3 items with high level >2,5: poor work performance and harming the patient, causing physical harm to the patient, and confusing the types of medications). Statistically significant differences were found in the total average score by gender (highest in females) and academic semester (highest during the fifth). It was found that the KESKAK domains with the highest scores were: lack of skills (2,2), work overload (2,2), contact with suffering (2,0), and the patient seeking a close relationship (2,0). Conclusion: nursing students have a moderate level of stress caused by situations of the clinical practice, factors related to lack of skills and work overload were predominated.
Objetivo: identificar os estressores nas práticas clínicas nos alunos da Faculdade de Enfermagem de uma Universidade pública do Antioquia (Colômbia) e explorar a relação entre os níveis de estresse e sexo e semestre acadêmico. Métodos: estudo quantitativo de tipo transversal realizado durante o primeiro semestre acadêmico de 2016. A população do estudo consistiu de todos os alunos da 5a a 8a semestre na prática clínica, nenhuma amostragem foi feita. Os participantes responderam por autorreporte a escala KEZKAK de Zupiría et al. para avaliar 41 estressores nas práticas clínicas dos estudantes de enfermagem. As pontuações maiores de 1,5 indicavam que havia estresse. Resultados: 156 dos 224 alunos inscritos participaram (69,6% do total). A média da escala foi de 2,0 o que equivale a nível de estresse moderado. Em 88% dos itens mostraram algum grau de estresse (3 itens com nível alto >2,5: Fazer mal meu trabalho e prejudicar ao paciente, fazer dano físico ao paciente, e Confundir-me de medicação). Se apresentaram diferencias estatisticamente significativas na pontuação média total nas variáveis sexo (maior no feminino) e semestre acadêmico (maior no quinto). Se encontrou que os domínios de KESKAK com maiores pontuações foram: falta de competência (2,2), sobrecarga de trabalho (2,2), contato com o sofrimento (2,0) e que o paciente busque uma relação íntima (2,0). Conclusão: os estudantes de enfermagem têm um nível de estresse moderado ocasionado por situações da prática clínica, foram fatores predominantes os relacionados com a falta de competência e sobrecarga de trabalho.
Subject(s)
Stress, Psychological , Cross-Sectional Studies , Nursing, Practical/methodsABSTRACT
The molecular basis of pathogen-induced host cell apoptosis is well characterized for a number of microorganisms. Mycobacterium tuberculosis is known to induce apoptosis and it was shown that live but not heat killed M. tuberculosis stimulates this biological pathway in monocytes. The dependence of this activity on live bacilli led us to hypothesize that products released or secreted by M. tuberculosis are the primary apoptotic factors for human monocytes. Thus, the culture filtrate of in vitro grown M. tuberculosis strain H37Rv was fractioned by conventional chromatography and the apoptosis-inducing activity of individual fractions was measured on human monocytes. The tests employed included measurement of cell membrane damage, caspase activation, and cytokine release. Small molecular weight RNAs of M. tuberculosis were recognized as the predominant apoptosis inducing factors. The RNA was comprised primarily of tRNA and rRNA fragments that stably accumulate in the culture filtrate during early log-phase growth. The RNA fragments signaled through a caspase-8 dependent, caspase-1 and TNF-α independent pathway that ultimately compromised the human monocytes' ability to control M. tuberculosis infection. These studies provide the first report of bacterial RNA inducing apoptosis. They also provide a foundation to pursue pathways for secretion or release of nucleic acids from M. tuberculosis and the impact of secreted RNA fragments on pathogenesis.
Subject(s)
Apoptosis/drug effects , Caspase 8/metabolism , Extracellular Space/metabolism , Monocytes/enzymology , Monocytes/microbiology , Mycobacterium tuberculosis/metabolism , RNA, Bacterial/pharmacology , Chromatography, Affinity , Concanavalin A , Extracellular Space/drug effects , Humans , Kinetics , Monocytes/cytology , Monocytes/drug effects , Mycobacterium tuberculosis/drug effects , RNA, Bacterial/isolation & purification , Sepharose , Tuberculosis/enzymology , Tuberculosis/microbiology , Tumor Necrosis Factor-alpha/pharmacologyABSTRACT
Antecedentes: El Sindrome de Burnout consiste en una sensacion de agotamiento, decepcion, perdida de interes y eficacia por la actividad academica, que puede presentarse en estudiantes de Medicina, a quienes las caracteristicas de su formacion les resulta agobiante. Por ello es necesario investigar la prevalencia de dicho sindrome en los estudiantes de Medicina de la Universidad de Manizales. Materiales y metodos: Estudio de corte transversal, con una muestra probabilisticade 234 estudiantes de Medicina de la Universidad de Manizales (Manizales, Caldas,Colombia). El presente estudio identifica y analiza la prevalencia de SDP, estres,depresion y ansiedad, su correlacion y factores asociados, en estudiantes de I a X semestre de Medicina, matriculados en el segundo periodo academico del 2009. Resultados: En los participantes, 39.1 hombres y 60.9 mujeres, provenientes en mayor porcentaje del departamento de Caldas (42.3), se evidencio un 34 de Burnoul, con frecuencias máximas por componente agotamiento alto 42.3, eficacia alta 39 y cinismo bajo 35.7. Se encontro un 60.5 de ansiedad, 30.5de depresion,11.8 de riesgo suicida, y un promedio de 40 de acoso laboral. Las tres componentes del sindrome mostraron relacion significativa con estres de examen, ansiedad, depresión y acoso laboral. No se encontró relacion con genero, estado civil y consumo de alcohol...
Subject(s)
Adjustment Disorders , Burnout, Professional , Efficiency , Students, Medical , SuicideABSTRACT
Taenia solium has a complex life cycle. Its cysticercus can lodge in the brain, causing neurocysticercosis (NCC), and the adult tapeworm's survival in the intestine results in taeniasis. In this study, the in situ detection of previously described glycoprotein antigens used for serological diagnosis of NCC and the detection of other glycoconjugates was explored in cysticerci and the surrounding porcine tissue to understand their potential role in pathogenesis. Immunohistochemistry with an antiserum specific for glycoprotein antigens rich in N-linked carbohydrates and in situ histochemistry with a battery of lectins that have affinity to a variety of glycoconjugates were performed. The glycoconjugates rich in N-linked carbohydrates were detected in the vesicular fluid and tegument of the vesicular membrane and scolex, where the parasite has direct contact with the host tissues during cysticercosis and taeniasis, respectively. Additionally, as the inflammatory response progressed, the parasite's antigenic glycoproteins were also detected in the cytoplasm of inflammatory cells in the surrounding granuloma. In contrast, the spiral canal tegument, which will be exposed to intestinal enzymes in taeniasis, had N-acetyl-galactosamine-rich mucins. Thus, the differential saccharidic composition in T. solium metacestode structures may be important for the survival of the parasite in different host sites.
Subject(s)
Antigens, Helminth/analysis , Cysticercosis/immunology , Cysticercus/immunology , Glycoproteins/analysis , Taenia solium/immunology , Animals , Antigens, Helminth/immunology , Antigens, Helminth/isolation & purification , Blotting, Western , Cysticercosis/parasitology , Epitopes/analysis , Epitopes/immunology , Glycoconjugates/analysis , Glycoconjugates/immunology , Glycoconjugates/isolation & purification , Glycoproteins/immunology , Glycoproteins/isolation & purification , Host-Parasite Interactions/immunology , Immune Sera/biosynthesis , Immune Sera/immunology , Immunohistochemistry , Lectins/immunology , SwineABSTRACT
La neurocisticercosis es una infección causada por el cisticerco de la T. Solium y puede confundirse con otras afecciones del sistema nervioso central. Las glicoproteínas de 12-28 kD de este parásitos son útiles para el diagnóstico serológico de la neurocisticercosis. Estas glicoproteínas contiene abundantes carbohidratos asociados vía asparagina (tipo N). Objetivo: Determinar la contribución de los carbahidratos tipo N en la antigenicidad de las glicoproteínas. Materiales y Métodos: se purificaron las glicoproteínas de 12, 16 y 18 kD de los cisticercos utilizando un gel preparativo de poliacrilamida y se sometieron a deglicosilación enzimática con PNGase F. Luego se evaluaron los cambios en antigenicidad entre las proteínas nativas y deglicosiladas por Western blot. Resultados: los antígenos deglicosilados redujeron su peso molecular a 7 kD y perdieron parte de su antigenicidad. Esta reducción fue más notoria para la proteína de 18 kD. La cual tiene mayor contenido de carbohidratos que la de 12 y 16 kD. Conclusión: estos resultados sugieren que los carbohidratos no sólo contribuyen a la antigenicidad, sino que además causan un bloqueo estérico que inhibe que el sistema inmune detecte otros epítopes no expuesto. Estos datos sugieren que la antigenicidad de las glicoproteínas de T. Solium se debe a una combinación de epítopes sacarídicos y probablemente proteicos