Subject(s)
Granulomatous Disease, Chronic/diagnostic imaging , Child , Combined Modality Therapy , Digestive System/diagnostic imaging , Granulomatous Disease, Chronic/genetics , Granulomatous Disease, Chronic/therapy , Humans , Male , Radiography , Sulfonamides/therapeutic use , Trimethoprim/therapeutic useABSTRACT
The pedigree of two interrelated families with 10 affected members suffering from malignant supratentorial gliomas is reported. In addition, three other unrelated families with two members each who were treated for different types of brain tumors are described. Genetic implications are discussed.
Subject(s)
Brain Neoplasms/genetics , Glioma/genetics , Adolescent , Adult , Aged , Female , Humans , Male , PedigreeSubject(s)
Brain Neoplasms/pathology , Adolescent , Child , Child, Preschool , Humans , Infant , Retrospective StudiesABSTRACT
Rupture of the diaphragm due to blunt trauma is rare in the pediatric age group. This article describes six such cases. This life-threatening condition should be suspected in the case of any serious thoracoabdominal trauma, even in the presence of negative radiographic findings on initial evaluation. In the very sick child, horizontal beam, lateral radiographs of the chest and abdomen have been extremely useful in establishing the diagnosis. The suspicion and investigation of associated diaphragmatic injury will result in earlier diagnosis and treatment.
