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1.
BJA Open ; 2: 100011, 2022 Jun.
Article in English | MEDLINE | ID: mdl-37588269

ABSTRACT

Airway stents are primarily inserted for the management of airway obstruction associated with an inoperable malignancy and are rarely indicated in benign disease. We outline the complications associated with tracheal stents and describe the use of veno-venous extracorporeal membrane oxygenation (V-V ECMO) to facilitate open tracheal surgery in an apnoeic patient who had an uncovered metallic tracheal stent left in place for an inappropriately long period. Computerised tomography imaging of the neck and thorax provided information for operative planning and described of the stent in addition to the extensive granulation tissue at the distal end of the stent. Veno-venous extracorporeal membrane oxygenation was used to facilitate open tracheal surgery, removal of the tracheal stent and formation of a surgical tracheostomy. Prolonged use of an uncovered metallic airway stent in younger patients with benign disease may lead to the stent being difficult to remove. There may be an accumulation of granulation tissue with the risk of airway obstruction.

2.
Clin Case Rep ; 7(4): 806-808, 2019 Apr.
Article in English | MEDLINE | ID: mdl-30997090

ABSTRACT

We describe the different clinical presentations, radiology, histology and management of this unique, highly aggressive disease. Clinical presentation of appendicitis may not just be appendicitis. Appendiceal tumors must always be considered in the differential diagnosis. Dedicated radiology and histological examination in addition to aggressive surgical and oncological input improve outcome.

4.
Vasc Endovascular Surg ; 51(7): 480-484, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28859600

ABSTRACT

Cystic adventitial disease (CAD) is a rare vascular pathology which predominantly affects peripheral vessels of young otherwise healthy males. Much debate exists regarding its exact etiology. It is characterized by a collection of mucinous material within the adventitial wall layer of the affected vessel, resulting in arterial stenosis and rapidly progressive calf claudication. Treatment is primarily surgical, although radiological interventions have been reported. Its rarity makes evidence-based surgical or radiological management difficult. With this in mind, we report two cases of popliteal artery CAD treated successfully with primary excision and bypass grafting. We analyzed all literature published on CAD since first reported in 1947 and we propose an algorithm for appropriate management pathways.


Subject(s)
Adventitia/surgery , Blood Vessel Prosthesis Implantation , Cysts/surgery , Peripheral Arterial Disease/surgery , Popliteal Artery/surgery , Saphenous Vein/transplantation , Adult , Adventitia/diagnostic imaging , Blood Vessel Prosthesis , Blood Vessel Prosthesis Implantation/instrumentation , Computed Tomography Angiography , Constriction, Pathologic , Cysts/diagnostic imaging , Cysts/physiopathology , Humans , Male , Middle Aged , Peripheral Arterial Disease/diagnostic imaging , Peripheral Arterial Disease/physiopathology , Polytetrafluoroethylene , Popliteal Artery/diagnostic imaging , Popliteal Artery/physiopathology , Prosthesis Design , Treatment Outcome
5.
J Biomech ; 49(15): 3697-3704, 2016 11 07.
Article in English | MEDLINE | ID: mdl-27776741

ABSTRACT

This study compares the mechanical properties of excised carotid and femoral human plaques and also develops a predictor of these properties based on plaque composition. Circumferential planar tension tests were performed on 24 carotid and 16 femoral plaque samples. Composition was characterised using Fourier Transform Infrared spectroscopy. Stretch at failure, strength, and stiffness are significantly higher in the carotid group (P=.012, P<.001 and P=.002, respectively). The ratio of calcified to lipid plaque content demonstrates the strongest correlation with the stretch at failure and strength (R2=.285, P<.001 and R2=.347, P<.001). No composition based parameter correlates significantly with stiffness. The significantly different mechanical properties of the two groups aids in explaining the varying endovascular treatment outcomes clinically observed in these vessels. Furthermore, determining the ratio of calcified to lipid plaque content may be useful in predicting individual plaque mechanical response to endovascular treatment.


Subject(s)
Carotid Arteries/physiology , Femoral Artery/physiology , Plaque, Atherosclerotic/physiopathology , Aged , Carotid Arteries/pathology , Female , Femoral Artery/pathology , Humans , Male , Middle Aged , Plaque, Atherosclerotic/pathology , Spectroscopy, Fourier Transform Infrared
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