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Med. cután. ibero-lat.-am ; 33(6): 261-263, nov.-dic. 2005. ilus
Article in Es | IBECS | ID: ibc-042915

ABSTRACT

Presentamos 2 pacientes de sexo femenino con granuloma anular generalizado confirmado histológicamente, sin respuesta a terapéuticas previas con corticoides tópicos, corticoides orales, inmunomoduladores, retinoides e inmunosupresores. En ambos casos se ha instaurado tratamiento con vitamina E, tópica en uno y oral en otro, con evolución favorable. En ningún caso se ha observado recurrencia de la dermatosis. Pensamos que el tratamiento con vitamina E, podría ser una posible alternativa a tener en cuenta ante granulomas anulares generalizados recalcitrantes


We present 2 female patients with generalized granuloma annulare confirmed histopathologically with no improvement after topical and oral steroids, immunomodulators, retinoids and immunosuppressive drugs. Vitamin E therapy was successfully performed in both cases, topical in the first one and oral in the other, with no following recurrence. We think that topical or oral vitamin E are possible alternatives to consider in the treatment of recalcitrant generalized granuloma annulare


Subject(s)
Female , Child , Aged , Humans , Vitamin E/administration & dosage , Granuloma Annulare/drug therapy , Adrenal Cortex Hormones/therapeutic use , Administration, Topical , Granuloma Annulare/pathology
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