ABSTRACT
BACKGROUND: Allergic rhinitis affects 20 million of people in United States and a higher figure all around the world. OBJECTIVE: To evaluate the efficacy and safety of fexofenadine compared with certirizine in the treatment of allergic rhinitis. MATERIAL AND METHOD: It was carried out a prospective, double blind, comparative, randomized and multicentric study in patients with allergic rhinitis, with ages between 12 and 65 years. In the first phase, placebo was administered during three days to all the patients; and then, they were randomly allocated to receive fexofenadine 120 mg or cetirizine 10 mg in one dose a day during 14 days. Laboratory and cabinet tests at the beginning and at the end were performed to value security, as well as a global evaluation of the researcher to estimate effectiveness. RESULTS: 176 patients were included, 63.6% were women, average age was 27 years (+/- 12), 47.7% received fexofenadine and 52.2%, cetirizine. There was not significant difference in parameters of effectiveness nor of security in the studied group. CONCLUSION: The results of the present study confirm the efficacy and safety of the antihistaminic fexofenadine in the treatment of allergic rhinitis.
Subject(s)
Anti-Allergic Agents/therapeutic use , Cetirizine/therapeutic use , Histamine H1 Antagonists/therapeutic use , Rhinitis, Allergic, Perennial/drug therapy , Rhinitis, Allergic, Seasonal/drug therapy , Terfenadine/analogs & derivatives , Terfenadine/therapeutic use , Adolescent , Adult , Aged , Anti-Allergic Agents/adverse effects , Cetirizine/adverse effects , Child , Double-Blind Method , Female , Histamine H1 Antagonists/adverse effects , Humans , Male , Middle Aged , Safety , Severity of Illness Index , Terfenadine/adverse effects , Treatment OutcomeSubject(s)
Adult , Middle Aged , Humans , Male , Female , Epistaxis , Ethmoid Sinus , Ligation , Maxillary ArterySubject(s)
Child, Preschool , Child , Adult , Humans , Male , Facial Paralysis , Skull Fractures , Temporal BoneABSTRACT
Presentamos el caso de un paciente quien despues de un traumatismo en la region retroauricular izquierda desarrolla un angioliomioma extraido quirurgicamente. Actualmente el paciente se encuentra libre de sintomatologia. Estos tumores son dificiles de diagnosticar clinicamente por la falta de sintomatologia especifica y lo raro de su presentacion; este es el segundo caso informado en la literatura mundial con esta localizacion. El tratamiento que se sugiere es el quirurgico, no se presentan recurrencias cuando su extirpacion es total
