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1.
New Microbes New Infect ; 32: 100614, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31763046

ABSTRACT

Desulfovibrio species are anaerobic Gram-negative bacilli that make up part of the human gastrointestinal and vaginal flora. Infection with these bacteria is usually secondary to an intra-abdominal source. Identification of these bacteria is possible using available contemporary methods. We report the first case of Desulfovibrio desulfuricans bacteraemia identified using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS).

2.
Article in English | MEDLINE | ID: mdl-29914964

ABSTRACT

We tested the in vitro susceptibility of ceftazidime-avibactam and ceftolozane-tazobactam and 13 other antibiotics against 91 Burkholderia cepacia complex (BCC) strains isolated from cystic fibrosis patients since 2012. The highest susceptibility (82%) was found for trimethoprim-sulfamethoxazole. Eighty-one and 63% of all BCC strains were susceptible to ceftazidime-avibactam and ceftolozane-tazobactam, respectively. For temocillin, ceftazidime, piperacillin-tazobactam, and meropenem, at least 50% of the strains were susceptible. B. stabilis seems to be more resistant than other BCC species.


Subject(s)
Azabicyclo Compounds/pharmacology , Burkholderia cepacia complex/drug effects , Ceftazidime/pharmacology , Cephalosporins/pharmacology , Cystic Fibrosis/microbiology , Tazobactam/pharmacokinetics , Anti-Bacterial Agents/pharmacology , Burkholderia cepacia complex/isolation & purification , Drug Combinations , Humans , Microbial Sensitivity Tests , Sulfamethoxazole/pharmacology , Tazobactam/pharmacology , Trimethoprim/pharmacology
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