1.
Bioorg Med Chem Lett
; 10(5): 473-6, 2000 Mar 06.
Article
in English
| MEDLINE
| ID: mdl-10743951
ABSTRACT
Chemical resolution of racemic 18-methoxycoronaridine (18-MC) was achieved by the formation of its diastereomeric sulfonamides with either (R)-(-)- or (S)-(+)-camphorsulfonyl chloride. Preliminary assessment of (+)-, (-)-, and (+/-)-18-MC x HCl showed similar effects on morphine self-administration in a rat model, and similar affinities at the kappa opioid receptors.
Subject(s)
Ibogaine/analogs & derivatives , Morphine Dependence/drug therapy , Animals , Ibogaine/chemical synthesis , Ibogaine/pharmacology , Morphine/pharmacology , Narcotics/pharmacology , Rats , Receptors, Opioid, delta/drug effects , Receptors, Opioid, kappa/drug effects , Receptors, Opioid, mu/drug effects , Self Administration
2.
J Thorac Cardiovasc Surg
; 53(1): 145-52, 1967 Jan.
Article
in English
| MEDLINE
| ID: mdl-6015775
3.
Circulation
; 34(6): 1005-21, 1966 Dec.
Article
in English
| MEDLINE
| ID: mdl-5928547