Common circuit or paradigm shift? The functional brain in emotional scene perception and emotional imagery.

Meta-analytic and experimental studies investigating the neural basis of emotion often compare functional activation in different emotional induction contexts, assessing evidence for a "core affect" or "salience" network. Meta-analyses necessarily aggregate effects across diverse paradigms and different samples, which ignore potential neural differences specific to the method of affect induction. Data from repeated measures designs are few, reporting contradictory results with a small N. In the current study, functional brain activity is assessed in a large (N = 61) group of healthy participants during two common emotion inductions-scene perception and narrative imagery-to evaluate cross-paradigm consistency. Results indicate that limbic and paralimbic regions, together with visual and parietal cortex, are reliably engaged during emotional scene perception. For emotional imagery, in contrast, enhanced functional activity is found in several cerebellar regions, hippocampus, caudate, and dorsomedial prefrontal cortex, consistent with the conception that imagery is an action disposition. Taken together, the data suggest that a common emotion network is not engaged across paradigms, but that the specific neural regions activated during emotional processing can vary significantly with the context of the emotional induction.

An intra-individual approach for detecting evaluation with event-related potentials.

The P3-based concealed information test (CIT) is an accurate indirect measure of non-evaluative memories (e.g., knowledge of an incriminating item). Less clear and established, however, is the accuracy of indirect measures that rely on the P3-like late positive potentials (LPPs) in discriminating evaluative (e.g., pleasant or unpleasant) memories. Using an LPP-based evaluative oddball paradigm in which participants were truthful on half of the trials about their evaluation toward pictures and concealed their evaluation on the other half of trials toward pictures, we applied an intra-individual Bayesian scheme to classify whether participants' evaluations were congruent or incongruent with a preceding context. LPPs were predictably larger to evaluatively incongruent than congruent pictures, and this LPP effect was reduced during misreporting presumably because of enhanced cognitive load. Notably, across two experiments the sensitivity (80%) was respectable during truth telling, but poor during concealment (sensitivity = 35%). Taken together, these data suggest that indirect measures such as the LPP-based evaluative oddball may be useful for detecting individual evaluation, but more work is warranted that explores conditions under which concealment of evaluation may be more accurately assessed.

The Startle-Evoked Potential: Negative Affect and Severity of Pathology in Anxiety/Mood Disorders.

BACKGROUND: The National Institute of Mental Health Research Domain Criteria initiative encourages a search for dimensional biological measures of psychopathology unconstrained by current diagnostic categories. Consistent with this aim, the presented research studies a large sample of anxiety and mood disorder patients, assessing differences in principal diagnoses and comorbidity patterns, clinicians' ratings, and questionnaire measures of negative affect and life dysfunction as they relate to a potential brain marker of pathology: the amplitude of the event-related potential (ERP) elicited by a startle-evoking stimulus. METHODS: Patients seeking evaluation or treatment for anxiety and mood disorders (N = 208) participated in two tasks at the University of Florida (Gainesville, FL): 1) imagining emotional and neutral events and 2) viewing emotional and neutral pictures while acoustic startle probes were presented and the ERP was recorded. For a comparison patient group (N = 120), startle probes were administered and ERPs recorded at the University of Greifswald (Greifswald, Germany) while performing the same imagery task. RESULTS: Reduced positive amplitude of a centroparietal startle-evoked ERP (156-352 ms after onset) significantly predicted higher questionnaire scores of anxiety/depression, reports of increased life dysfunction, greater comorbidity, and clinician ratings of heightened severity and poorer prognosis. The effect was general across principal diagnoses, found for both the Florida and German samples, and consistent in pattern despite differences in the tasks administered. CONCLUSIONS: The startle-evoked ERP reliably predicts severity and breadth of psychopathology, independent of task context. It is a potential significant contributor to a needed array of biological measures that might improve classification of anxiety and mood disorders.

What does the dot-probe task measure? A reverse correlation analysis of electrocortical activity.

The dot-probe task is considered a gold standard for assessing the intrinsic attentive selection of one of two lateralized visual cues, measured by the response time to a subsequent, lateralized response probe. However, this task has recently been associated with poor reliability and conflicting results. To resolve these discrepancies, we tested the underlying assumption of the dot-probe task-that fast probe responses index heightened cue selection-using an electrophysiological measure of selective attention. Specifically, we used a reverse correlation approach in combination with frequency-tagged steady-state visual potentials (ssVEPs). Twenty-one participants completed a modified dot-probe task in which each member of a pair of lateralized face cues, varying in emotional expression (angry-angry, neutral-angry, neutral-neutral), flickered at one of two frequencies (15 or 20 Hz), to evoke ssVEPs. One cue was then replaced by a response probe, and participants indicated the probe orientation (0° or 90°). We analyzed the ssVEP evoked by the cues as a function of response speed to the subsequent probe (i.e., a reverse correlation analysis). Electrophysiological measures of cue processing varied with probe hemifield location: Faster responses to left probes were associated with weak amplification of the preceding left cue, apparent only in a median split analysis. By contrast, faster responses to right probes were systematically and parametrically predicted by diminished visuocortical selection of the preceding right cue. Together, these findings highlight the poor validity of the dot-probe task, in terms of quantifying intrinsic, nondirected attentive selection irrespective of probe/cue location.

On the automatic activation of attitudes: a quarter century of evaluative priming research.

Evaluation is a fundamental concept in psychological science. Limitations of self-report measures of evaluation led to an explosion of research on implicit measures of evaluation. One of the oldest and most frequently used implicit measurement paradigms is the evaluative priming paradigm developed by Fazio, Sanbonmatsu, Powell, and Kardes (1986). This paradigm has received extensive attention in psychology and is used to investigate numerous phenomena ranging from prejudice to depression. The current review provides a meta-analysis of a quarter century of evaluative priming research: 73 studies yielding 125 independent effect sizes from 5,367 participants. Because judgments people make in evaluative priming paradigms can be used to tease apart underlying processes, this meta-analysis examined the impact of different judgments to test the classic encoding and response perspectives of evaluative priming. As expected, evidence for automatic evaluation was found, but the results did not exclusively support either of the classic perspectives. Results suggest that both encoding and response processes likely contribute to evaluative priming but are more nuanced than initially conceptualized by the classic perspectives. Additionally, there were a number of unexpected findings that influenced evaluative priming such as segmenting trials into discrete blocks. We argue that many of the findings of this meta-analysis can be explained with 2 recent evaluative priming perspectives: the attentional sensitization/feature-specific attention allocation and evaluation window perspectives.

Electrophysiological responses to evaluative priming: the LPP is sensitive to incongruity.

Previous studies examining event-related potentials and evaluative priming have been mixed; some find evidence that evaluative priming influences the N400, whereas others find evidence that it affects the late positive potential (LPP). Three experiments were conducted using either affective pictures (Experiments 1 and 2) or words (Experiment 3) in a sequential evaluative priming paradigm. In line with previous behavioral findings, participants responded slower to targets that were evaluatively incongruent with the preceding prime (e.g., negative preceded by positive) compared to evaluatively congruent targets (e.g., negative preceded by negative). In all three studies, the LPP was larger to evaluatively incongruent targets compared to evaluatively congruent ones, and there was no evidence that evaluative incongruity influenced the N400 component. Thus, the present results provide additional support for the notion that evaluative priming influences the LPP and not the N400. We discuss possible reasons for the inconsistent findings in prior research and the theoretical implications of the findings for both evaluative and semantic priming.

Coherent with laughter: subjective experience, behavior, and physiological responses during amusement and joy.

Emotion research historically has adopted a fairly homogeneous view of positive emotions. The aim of the current study was to explore how two positive emotions, amusement and joy, differ in subjective, behavioral, cardiovascular, and respiratory characteristics. Thirty-nine participants viewed two film clips, each selected to elicit amusement or joy. As predicted, participants reported more amusement, showed more positive facial expressions and laughter, and exhibited less heart rate deceleration and a larger increase in respiratory amplitude in response to the amusement clip than in response to the joy clip. In addition, subjective, behavioral, and physiological indicators were more closely related in amusement than joy, which was largely attributable to laughter during amusement. The current study adds to a growing literature suggesting the importance of adopting a more nuanced conceptualization of positive emotion.