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1.
J Vasc Interv Radiol ; 20(10): 1343-51, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19695903

ABSTRACT

PURPOSE: To assess the effects on the proportions of lethal ice (ie, colder than -30 degrees C) in phantoms with different heat loads created by varying the size and number of cryoprobes spaced 2 cm apart. MATERIALS AND METHODS: Thermocouples at 0.5-, 1.0-, and 1.5-cm intervals from 1.7- or 2.4-mm-diameter cryoprobes were held by jigs accommodating a maximum of four cryoprobes. Agar phantoms (N = 24) used three sets of baseline temperatures: approximately 6 degrees C, 24 degrees C, and 39 degrees C. Temperatures during 15-minute freeze cycles were correlated with actual thermocouple locations seen within the ice by computed tomography (CT). Diameters and surface areas of the -30 degrees C lethal isotherm were assessed over time as percentages of the overall ice ball. RESULTS: The high-heat load phantom experiments (39 degrees C) showed the greatest impact on lethal zones by percentage for all probe configurations. At 15 minutes, single-, double-, triple-, and quadruple-probe arrangements of 2.4-mm cryoprobes had average lethal ice diameters of 1.2, 3.3, 4.1, and 4.9 cm, respectively, comprising 13%, 46%, 51%, and 56% surface areas of lethal ice, respectively. Surface areas and diameters of lethal ice made by 1.7-mm cryoprobes were 71% and 84% of those made by 2.4-mm cryoprobes, respectively. Lethal ice resides less than 1 cm behind the leading edge for nearly all probe configurations and heat loads. CONCLUSIONS: Single cryoprobes create very low percentages of lethal ice. Multiple cryoprobes overcome the high heat load of body temperature phantoms and help compensate for the lower freeze capacity of thinner cryoprobes.


Subject(s)
Body Temperature/physiology , Cryosurgery/instrumentation , Models, Biological , Viscera/physiology , Viscera/surgery , Biomimetic Materials , Computer Simulation , Energy Transfer/physiology , Equipment Design , Equipment Failure Analysis , Humans
2.
J Biomech Eng ; 128(5): 788-91, 2006 Oct.
Article in English | MEDLINE | ID: mdl-16995768

ABSTRACT

A robotic tendon is a spring based, linear actuator in which the stiffness of the spring is crucial for its successful use in a lightweight, energy efficient, powered ankle orthosis. Like its human analog, the robotic tendon uses its inherent elastic nature to reduce both peak power and energy requirements for its motor. In the ideal example, peak power required of the motor for ankle gait is reduced from 250 W to just 77 W. In addition, ideal energy requirements are reduced from nearly 36 J to just 21 J. Using this approach, an initial prototype has provided 100% of the power and energy necessary for ankle gait in a compact 0.95 kg package, seven times less than an equivalent motor/gearbox system.


Subject(s)
Achilles Tendon/physiology , Ankle Joint/physiology , Gait/physiology , Models, Biological , Movement/physiology , Orthotic Devices , Robotics/methods , Biomimetics/methods , Computer Simulation , Elasticity , Equipment Failure Analysis , Humans , Prosthesis Design , Stress, Mechanical , Therapy, Computer-Assisted/methods
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