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1.
Med Phys ; 36(6): 2172-80, 2009 Jun.
Article in English | MEDLINE | ID: mdl-19610306

ABSTRACT

Proton radiotherapy centers that currently use passively scattered proton beams do field specific calibrations for a non-negligible fraction of treatment fields, which is time and resource consuming. Our improved understanding of the passive scattering mode of the IBA universal nozzle, especially of the current modulation function, allowed us to re-commission our treatment control system for accurate delivery of SOBPs of any range and modulation, and to predict the output for each of these fields. We moved away from individual field calibrations to a state where continued quality assurance of SOBP field delivery is ensured by limited system-wide measurements that only require one hour per week. This manuscript reports on a protocol for generation of desired SOBPs and prediction of dose output.


Subject(s)
Algorithms , Radiometry/methods , Radiometry/standards , Radiotherapy, Conformal/instrumentation , Radiotherapy, Conformal/standards , Computer-Aided Design , Equipment Design , Equipment Failure Analysis , Proton Therapy , Radiotherapy Dosage , Reproducibility of Results , Scattering, Radiation , Sensitivity and Specificity , United States
2.
Med Phys ; 32(12): 3636-40, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16475762

ABSTRACT

We have investigated methods of reconstructing beam profiles in the penumbral region using a set of axially symmetric chambers, differing only in the detector radius. In principal, the transfer functions, or kernels, of such chambers should be functions of radius only. Three chambers of radii 0.297, 0.556, and 0.714 cm have been used. The transfer functions of the chambers can be determined by deconvolving the profiles measured with each detector with the PPMC profile. The results indicate that the transfer functions can be parametrized accurately as a Gaussian cutoff at 1.75(r), with (r) the average radius of the chamber. Deconvolution of the measured profiles with the transfer functions yields a profile that agrees with the PPMC profile to +/- 0.5 mm over the 20-80% penumbra.


Subject(s)
Radiometry/instrumentation , Biophysical Phenomena , Biophysics , Humans , Mathematics , Neoplasms/radiotherapy , Radiographic Image Interpretation, Computer-Assisted , Radiometry/statistics & numerical data , Radiotherapy Planning, Computer-Assisted
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