Prevalencia de obesidad y obesidad abdominal en la población española de 65 y más años de edad: estudio ENPE / Prevalence of obesity and abdominal obesity in Spanish population aged 65 years and over: ENPE study

Antecedentes y objetivos: Evaluar la prevalencia de obesidad y obesidad abdominal (OA) en población española ≥65años, analizar la influencia de algunos factores sociodemográficos y su asociación con factores de riesgo.MétodosLa muestra procede del estudio ENPE, estudio transversal en muestra aleatoria representativa de la población no institucionalizada (2014-2015). Este análisis se refiere a población ≥65años (n=1.233). Observadores entrenados realizaron mediciones antropométricas en los domicilios según protocolos internacionales estandarizados. Se consideró obesidad (índice de masa corporal [IMC] ≥30); OA (cintura >102cm varones; >88cm mujeres).ResultadosSe ha estimado una alta prevalencia de obesidad en adultos ≥65años, mayor en mujeres (40,1% [IC95% 36,4-43,8]) que en hombres (32,5% [IC95% 28,5-36,8]). La prevalencia de OA también es mayor en mujeres (69,9% [IC95% 66,4-73,1]) que en hombres (40,7% [IC95% 36,5-44,8]), y es aún mayor al definir OA considerando el índice cintura-cadera o el índice cintura-talla. El 39,8% de tipificados como OA tienen IMC entre 25-29. Obesidad y OA son más frecuentes en el sur respecto al este, norte-este y centro y tienen relación inversa con el nivel educativo. Obesidad y OA se asocian con mayor probabilidad de hipercolesterolemia e hipertensión arterial. La obesidad sarcopénica también se asocia, además, con diabetes.ConclusiónLa prevalencia de obesidad y OA en adultos ≥65años es alta, mayor en mujeres, en personas con menor nivel educativo y en la región sur respecto al este, norte-este y centro. Es especialmente preocupante la alta prevalencia de OA por su asociación con complicaciones cardiovasculares, metabólicas y deterioro de la calidad de vida.

Prevalence of obesity and abdominal obesity in Spanish population aged 65 years and over: ENPE study. / Prevalencia de obesidad y obesidad abdominal en la población española de 65 y más años de edad: estudio ENPE.

BACKGROUND AND OBJECTIVES: To assess the prevalence of obesity and abdominal obesity (AO) in the Spanish population aged ≥65 years, to analyse the influence of selected sociodemographic factors and association with risk factors. METHODS: The sample comes from the ENPE study, a cross-sectional study of a representative sample of the non-institutionalized population (2014-2015). This analysis refers to the population ≥65 years (n=1,233). Trained observers performed anthropometric measurements at participants' homes following standard international protocols. Obesity was defined as body mass index (BMI) ≥30; AO waist>102cm men; >88cm women. RESULTS: Estimated prevalence of obesity in adults ≥65 years was high, higher in women (40.1% [95% CI 36.4-43.8]) than in men (32.5% [95% CI 28.5-36.8]). The prevalence of AO was also higher in women (69.9% [95% CI 66.4-73.1]) than in men (40.7% [95% CI 36.5-44.8]), and estimates were even higher when defining AO by waist-hip ratio or waist-height ratio. Of those classified as AO, 39.8% have a BMI between 25-29. Obesity and AO are higher in the South region compared to East, North-East and Central regions and showed inverse association with educational level. Obesity and AO were associated with increased probability of hypercholesterolaemia and high blood pressure, sarcopenic obesity, and diabetes. CONCLUSION: The prevalence of obesity and AO in adults aged ≥65 years is high, higher in women, in people of lower educational level and in the South region compared to East, North-East and Central regions. The high prevalence of OA is especially worrying due to its association with cardiovascular and metabolic complications and poorer quality of life.

Prevalence of obesity and associated cardiovascular risk factors in the Spanish population: the ENPE study.

INTRODUCTION AND OBJECTIVES: Obesity is a significant public health problem associated with an increased risk of cardiovascular risk factors (CVRF). The aim of this study was to determine the prevalence of overweight and abdominal obesity (AO) in the Spanish population aged ≥ 3 years and to analyze the influence of sociodemographic and lifestyle factors and their association with CVRF. METHODS: The sample was drawn from the ENPE study (n=6800). The study protocol included individual anthropometric measurements, sociodemographic factors, food intake (food frequency questionnaire), physical activity, lifestyles, and health problems. RESULTS: The estimated overall prevalence of obesity (22.0%; 95%CI, 21.0-23.0) and AO (64.7%; 95%CI, 63.5-65.8) was higher in men, in persons aged ≥ 65 years, and in those with a lower socioeconomic level or from southern regions. Lifestyle pattern was significantly associated with obesity and AO (P=.011), which were less likely in people with an active lifestyle pattern (P <.0001). Obesity (OR, 1.85; 95%CI, 1.24-2.78) and AO (OR, 2.16; 95%CI, 1.1-4.24) were positively associated with CVRF. Clustering of CVRF with obesity and/or AO was higher in women (12.6%; 95%CI, 11.4-13.9) and in persons aged ≥ 65 years (32.7%; 95%CI, 30.0-35.4). CONCLUSIONS: The prevalence of obesity and AO in the Spanish population is high; it is higher in men, increases with age, and is inversely related to socioeconomic status. A lifestyle pattern combining a higher level of physical activity, moderate sedentariness and a Mediterranean dietary pattern is associated with a lower probability of obesity, AO, and CVRF.

Local renin angiotensin system and sperm DNA fragmentation.

The renin angiotensin system (RAS) appears to influence male fertility at multiple levels. In this work, we analyzed the relationship between the RAS and DNA integrity. Fifty male volunteers were divided into two groups (25 each): control (DNA fragmentation ≤20%) and pathological (DNA fragmentation >20%) cases. Activities of five peptidases controlling RAS were measured fluorometrically: prolyl endopeptidase (which converts angiotensin [A] I and A II to A 1-7), neutral endopeptidase (NEP/CD10: A I to A 1-7), aminopeptidase N (APN/CD13: A III to A IV), aminopeptidase A (A II to A III) and aminopeptidase B (A III to A IV). Angiotensin-converting enzyme (A I to A II), APN/CD13 and NEP/CD10 were also assessed by semiquantitative cytometry and quantitative flow cytometry assays, as were the receptors of all RAS components: A II receptor type 1 (AT1R), A II receptor type 2 (AT2R), A IV receptor (AT4R or insulin-regulated aminopeptidase [IRAP]), (pro)renin receptor (PRR) and A 1-7 receptor or Mas receptor (MasR) None of the enzymes that regulate levels of RAS components, except for APN/CD13 (decrease in fragmented cells), showed significant differences between both groups. Micrographs of RAS receptors revealed no significant differences in immunolabeling patterns between normozoospermic and fragmented cells. Labeling of AT1R (94.3% normozoospermic vs 84.1% fragmented), AT4R (96.2% vs 95.3%) and MasR (97.4% vs 87.2%) was similar between the groups. AT2R (87.4% normozoospermic vs 63.1% fragmented) and PRR (96.4% vs 48.2%) were higher in non-fragmented spermatozoa. These findings suggest that fragmented DNA spermatozoa have a lower capacity to respond to bioactive RAS peptides.

Patterns of Change in Dietary Habits and Physical Activity during Lockdown in Spain Due to the COVID-19 Pandemic.

BACKGROUND: Lockdown due to COVID-19 influenced food habits and lifestyles with potential negative health impact. This study aims to identify patterns of change in eating habits and physical activity during COVID-19 lockdown in Spain and to identify associations with sociodemographic factors and usual habits. METHODS: This cross-sectional study included 1155 adults recruited online to answer a 10-section questionnaire. The protocol assessed usual diet by means of a semi-quantitative food frequency questionnaire, usual physical activity (PA) and supplement use, dietary changes, sedentary time, PA, exposure to sunlight, sleep quality, and smoking during confinement. Patterns of dietary change were identified by factor analysis. Factor scores were included in cluster analysis together with change in PA. RESULTS: Six patterns of dietary change were identified that together with PA changes during lockdown defined three clusters of lifestyle change: a cluster less active, a more active cluster, and a third cluster as active as usual. People who were usually less active were more likely to be classified in the cluster that increased physical activity in confinement. Scores of the Healthy Mediterranean-Style dietary pattern were higher in this group. Conclusions: Different patterns of change in lifestyles in confinement suggest the need to tailor support and advice to different population groups.

Cambios en los hábitos alimentarios durante el periodo de confinamiento por la pandemia COVID-19 en España / Changes in eating habits during lockdown period due to the COVID-19 pandemic in Spain

FUNDAMENTOS: El cierre de fronteras, el confinamiento de la población y el distanciamiento físico han sido las principales medidas instauradas en muchos países para contener el alcance y gravedad de la pandemia COVID-19. En este estudio se analizan los cambios en los hábitos alimentarios y en otros estilos de vida durante el periodo de confinamiento en un grupo de población en España. MATERIAL Y MÉTODOS: Se ha realizado un estudio transversal, observacional en una muestra de conveniencia de personas mayores de 18 años de edad, reclutada de forma electrónica entre el 21 de abril y 8 de mayo de 2020 (semanas 6-8 de confinamiento) en España (n= 1036). El protocolo contemplaba datos sociodemográficos, características del confinamiento, hábitos de consumo alimentario y actividad física usuales, y modificaciones durante el periodo de confinamiento. RESULTADOS: Los cambios más frecuentes se refieren a mayor consumo de fruta (27%), huevos (25,4%), legumbres (22,5%), verduras (21%) y pescado (20%) y reducción en el consumo de carnes procesadas (35,5%), cordero o conejo (32%), pizza (32,6%), bebidas alcohólicas destiladas (44,2%), bebidas azucaradas (32,8%) o chocolate (25,8%), con algunas diferencias sobre todo en función de la edad y el grado de adecuación de la dieta usual. Un 14,1% que habitualmente no cocina, lo hace en este periodo. El 15% no realiza ejercicio físico, 24,6% pasa sentado más de 9 horas diarias y el 30,7% de las personas fumadoras (14,7%) fuma más. Un 37% refiere no dormir bien. CONCLUSIONES: Los participantes en este estudio refieren cambios alimentarios en el periodo de confinamiento en España con tendencia hacia mayor consumo de alimentos saludables, menor consumo de alimentos de menos interés nutricional y aumento de la práctica de cocinar en casa

BACKGROUND: The lockout of borders, lockdown of the population and social isolation are key measures adopted in many countries to contain the COVID-19 pandemic. This study describes changes in eating habits and other lifestyles during confinement in a population group in Spain. METHODS: A cross-sectional, observational study was conducted on a convenience sample of people aged 18 yr. and over, recruited online between April 21 and May 8, 2020 (weeks 6-8 of lockdown) in Spain (n = 1036). The protocol considered sociodemographic data, characteristics of confinement, usual food consumption and physical activity, and changes during confinement. RESULTS: Most frequently reported changes in dietary habits are increased consumption of fruit (27%), eggs (25.4%), legumes (22.5%), vegetables (21%) and fish (20%) and reduced consumption of processed meats (35.5%), lamb or rabbit (32%), pizza (32.6%), distilled alcoholic beverages (44.2%), sugary drinks (32.8%) or chocolate (25.8%). Some differences were observed depending on age and adequacy of the usual diet. Some 14.1% who do not usually cook do so during this period; 15% do not do physical exercise, 24.6% sit more than 9 hours a day and 30.7% of smokers (14.7%) report increased tobacco use. 37% reported not sleeping well. CONCLUSIONS: Participants in this study report dietary changes during lockdown in Spain with a trend towards greater consumption of healthier foods, less consumption of foods of poor nutritional interest and an increase in the practice of cooking at home