[Neuropathology and pregnancy. 189 consecutive cases (1971--1976) (author's transl)]. / Pathologie neurologique et grossesse. A propos de 189 observations en série continue (1971--1976).

The authors report 189 case histories of pregnant women who had a neurological disorder, which either existed before the pregnancy or were discovered during the pregnancy. The most frequent aetiological conditions were, epilepsy, psychoses, vascular accidents, tumours and disseminated sclerosis. Pregnancy and neuropathology are an association for which the prognosis as a whole is good and linked to the time in the pregnancy when the neurological condition, whether it is stable or not, is discovered. The combination is absolutely compatible with the normal progress of pregnancy so long as the appropriate treatment is continued during the pregnancy. Cerebral vascular accidents that occur in pregnancy make the prognosis very much worse. In these circumstances neurosurgery may give some hope. This applies also for cerebral tumours, among which pituitary adenoma is becoming more and more frequent. Psychopathies can be a very baffling chapter when they are combined with pregnancy. Finally disseminated sclerosis, once it has been stabilised, is perfectly compatible with the normal outcome for a pregnancy.

[Clear cell vaginal adenocarcinoma in young girls. Apropos of a personal case]. / Adénocarcinome vaginal è cellules claires chez la jeune fille. A propos d'une observation personnelle

A personal case which has been studied has given the authors the opportunity of analysing the characteristics of clear-cell adenocarcinoma of the vagina in a young girl. Adhesions are most often discovered in cases of metrorrhagia or discharge about the time of puberty. Thence as a friable tumour on the anterior wall of the vagina. Usually diethylstilboestrol has been given during intrauterine life. Histologically clear cell carcinomata of the vagina are characterised by a glandular structure in which large cells with large nuclei and clear cytoplasm as well as small cells with "tapestry-maker nail patterns" are found together. Treatment is surgical: total colpohysterectomy with conservation of the ovaries, with lymphadenectomy and with conservation of a vaginal cavity. Prevention consists in screening those who have been exposed to the risk and treating lesions that have been found, but above all in care in using estrogens in pregnant women.

[Prolactin adenoma. Hypophysectomy during pregnancy]. / Adénome à prolactine. Hypophysectomie pendant la grossesse

The authors report a case of amenorrhoea with galatorrheoa due to a prolactin adenoma secondary to an inducer of ovulation (HMG and HCG) and in which pregnancy occurred. There was sudden progression of the adenoma with formation of a haematoma and the necessity for emergency surgery. In the light of this case, the risks and indications of inducers of ovulation in the sterile woman complaining of amenorrhoea with galactorrhoea are discussed.