[Results and lessons of an innovating chemotherapy-induced nauseas and vomiting management strategy]. / Résultats et enseignements d'une stratégie innovante de prise en charge des nausées et vomissements chimio-induits.

Current chemotherapy-induced nausea and vomiting management guidelines recommend taking into account the emetogenic potential of the chemotherapy employed as well as individual risk factors to such effects. We performed an interventional prospective study to assess the impact of an innovating therapeutic optimization strategy. The latter combines current guidelines application to a specific consultation in order to individualize the treatment. This study included 170 patients and covered a total of 1,746 days of various chemotherapies. Among these patients, 86.5% never vomited and 53.8% never had any nausea or vomiting. These results seem generally better than the ones found in the literature with all kinds of chemotherapies. Regarding them, we have attempted to highlight the determining criteria for a successful antiemetic treatment.

[Right diverticular colitis revealing an Ehlers-Danlos syndrome]. / Colite diverticulaire droite révélatrice d'un syndrome d'Ehlers-Danlos.

INTRODUCTION: Colic diverticulosis rarely occurs in the young and, in such cases, therefore requires search for a predisposing affection. OBSERVATION: A 25 year-old woman was hospitalised for abdominal pain and fever predominating in the right iliac fossa and leading to the diagnosis of right diverticular colitis. The clinical examination revealed features suggestive of an Ehlers-Danlos syndrome. DISCUSSION: The Ehlers-Danlos syndrome combines cutaneous sensitivity and articular hypermobility related to abnormality in the supporting connective tissue. Colic diverticulosis is found among the complications. Diverticular colitis occurring in a young adult should lead to the search for an originating disease of the connective tissue.