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Urol J ; 16(5): 495-500, 2019 10 21.
Article in English | MEDLINE | ID: mdl-30798568

ABSTRACT

PURPOSE: In this study, we aimed to evaluate the effects of antioxidants including Vitamin E-Selenium-Folic acid (Vit E -Se- FA) on semen parameters following varicocelectomy (VCT). MATERIALS AND METHODS: Sixty patients from 64 infertile male patients diagnosed with varicocele (VC) who un-derwent sub-inguinal VCT were included in the study. Following sub-inguinal VCT, the patients were randomized into two groups: 30 receiving Vit E-Se-FA supplementation for six months, and 30 as the control group with supplemental treatment. The post-operative semen parameters of Vit E-Se-FA receiving group were compared with control group at the end of experiment. The sperm count, percentage of motile and abnormal sperms were considered. RESULTS: There were statistically significant differences in terms of count (P = .031) and motility (P = .01) of sperm after six months of receiving Vit E-Se-FA supplementation comparing with control group. CONCLUSION: Vit E-Se-FA supplementation can improve sperm parameters (count and motility of sperm) after VCT.


Subject(s)
Antioxidants/pharmacology , Antioxidants/therapeutic use , Dietary Supplements , Folic Acid/pharmacology , Folic Acid/therapeutic use , Selenium/pharmacology , Selenium/therapeutic use , Spermatozoa/drug effects , Varicocele/surgery , Vitamin E/pharmacology , Vitamin E/therapeutic use , Adult , Humans , Male , Postoperative Period , Single-Blind Method , Urologic Surgical Procedures, Male/methods
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