ABSTRACT
A filament driven multi-cusp negative ion source has been developed for proton cyclotrons in medical applications. In Cs-free operation, continuous H(-) beam of 10 mA and D(-) beam of 3.3 mA were obtained stably at an arc-discharge power of 3 kW and 2.4 kW, respectively. In Cs-seeded operation, H(-) beam current reached 22 mA at a lower arc power of 2.6 kW with less co-extracted electron current. The optimum gas flow rate, which gives the highest H(-) current, was 15 sccm in the Cs-free operation, while it decreased to 4 sccm in the Cs-seeded operation. The relationship between H(-) production and the design/operating parameters has been also investigated by a numerical study with KEIO-MARC code, which gives a reasonable explanation to the experimental results of the H(-) current dependence on the arc power.
Subject(s)
Anions , Cesium , Cyclotrons , DeuteriumSubject(s)
Adrenal Gland Neoplasms/complications , Diabetic Ketoacidosis/etiology , Pheochromocytoma/complications , Adrenal Gland Neoplasms/diagnosis , Aged , Cardiomyopathies/diagnosis , Cardiomyopathies/etiology , Catecholamines/metabolism , Echocardiography , Electrocardiography , Female , Humans , Pheochromocytoma/diagnosisABSTRACT
We have studied the histogenesis of uterine corpus carcinoma with special reference to the relation to endometrial atypical hyperplasia. The summary of the results is as follows. The subjects of the study were 113 cases of operated uterine corpus cancer and 2,440 of noncorporeal (uterine) cancer. Atypical hyperplasia of the residual endometrium in corpus carcinoma was revealed in 42 of the 113 cases (37.2%). Among 19 premenopausal patients, the residual endometrium was in the secretory phase in 3 and in the proliferative phase in the others. The site of its appearance was either in the functional or non-functional layers with diffuse (16) and localized (26) types. A malignant change from the atypical hyperplastic (hormone dependent ?) and atrophic endometrium (hormone independent ?) was suggested.
