Environmental Sample Stability for Pharmaceutical Compound Analysis: Handling and Preservation Recommendations.

Efficient and resilient techniques for handling samples are essential for detecting pharmaceutical compounds in the environment. This study explores a method for preserving water samples during transport before quantitative analysis. The study investigates the stability of 17α-ethynylestradiol (EE2), acetaminophen (ACM), oxytetracycline (OTC), sulfamethoxazole (SMX), and trimethoprim (TMP) after preconcentration within solid-phase extraction (SPE) cartridges. Through various experiments involving different holding times and storage temperatures, it was determined that four pharmaceutical compounds remained stable when stored for a month at 4°C and for six months when stored at -18°C in darkness. Storing these compounds in SPE cartridges at -18°C seemed effective in preserving them for extended periods. In addition, ACM, TMP, OTC, EE2, and SMX remained stable for three days at room temperature. These findings establish guidelines for appropriate storage and handling practices of pharmaceutical compounds preconcentrated from aqueous environmental samples using SPE.

Underwater noise of traditional fishing boats in Cilacap waters, Indonesia.

The characteristics of traditional fishing boats based on distance are very important to be studied as the main contributor to noise pollution in Cilacap waters. Therefore, this study aimed to determine noise intensity and frequency based on the distance for each traditional fishing boat (3, 5, and 10 Gross Tonage/GT). The results showed that these boats emitted noise with broadband frequency and peak receive levels of 137.6 dB re 1 µPa (3 GT fishing boat at 42.6 m). Furthermore, the noise characteristics were different for each type of ship due to differences in size, engine type, and operational speed. The receive level had the same decreased pattern based on the distance for each noise frequency but with a different intensity. Meanwhile, the noise frequency increased linearly based on the distance and was directly proportional to the pattern of change. Therefore, the higher the frequency, the faster the disappearance of the intensity with increasing distance.