ABSTRACT
A retrospective study was performed dealing with clinical and histopathological aspects of Hodgkin's disease in patients presenting to the Radiation and Isotopes Centre of Khartoum (RICK) during the period from January 1984 to January 1989. A total of 105 patients were studied; this number accounted for 30.6% of all lymphoma patients and 2.0% of all cancers seen at RICK during the same period. The median age was 30 yrs, and the majority of patients were within two age groups, above 25 yrs and above 50 yrs, demonstrating a bimodal pattern. Males were commonly affected and this was more marked in children (M:F = 4.7:1.0). Two striking differences are observed between this study and those from the western world. The first was the high incidence of late clinical stages (III,IV) (70%) in this series despite the moderate duration of symptoms. The second was predominance of mixed cellularity and lymphocytic predominant sub-groups (65%) compared to reports from the western world. A possibility of a chronic stimulatory process of the lymphatic system is raised. The high incidence of late clinical stages on presentation with favourable histological types needs more work.
Subject(s)
Hodgkin Disease/epidemiology , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Child , Female , Hodgkin Disease/pathology , Humans , Male , Middle Aged , Neoplasm Staging , Retrospective Studies , Sex Factors , Sudan/epidemiologySubject(s)
Leukemia/epidemiology , Adolescent , Adult , Age Factors , Aged , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Sex Factors , SudanABSTRACT
Superficial cancer in the Sudan accounted for 17·2% of all malignant tumours examined histologically during the period 1962-72 inclusive. Of the 4 pathological types studied, squamous cell carcinoma was the commonest (63·3% of all superficial cancers) followed by malignant melanoma (18·8%) and basal cell carcinoma (14·9%) whilst Kaposi's sarcoma formed only 3% of the total. Generally, twice as many cases occurred in males as in females, with the exception of Kaposi's sarcoma where all the patients were males. Although a relatively high proportion of cases occurred in the young age groups, the age-specific incidence was noted to increase with age. Similarities and differences in the anatomical site of tumours compared with European and African series were noted. Certain differences emerged in the geographical distribution of these tumours in the Northern and Southern regions of the Sudan-regions which differ both ethnologically and geographically-thus suggesting possible roles played by racial and environmental factors in this respect.
