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1.
Int J Pediatr Otorhinolaryngol ; 90: 86-90, 2016 Nov.
Article in English | MEDLINE | ID: mdl-27729160

ABSTRACT

IMPORTANCE: The etiology of recurrent croup is often anatomic. Currently there is no set criteria for determining who should undergo diagnostic bronchoscopy and which patients are at most risk for having a clinically significant finding. Few studies have addressed these questions. OBJECTIVE: To identify risk factors for clinically significant findings on bronchoscopy in children with recurrent croup and the frequency of bronchoscopy findings in general. DATA SOURCES: PUBMED, Ovid MEDLINE, EMBASE. STUDY SELECTION: Articles addressing bronchoscopy in children with recurrent croup, up to July 2016, were reviewed. Related keywords and medical subject headings were used during the search. The abstracts were reviewed to determine suitability for inclusion based on a set of criteria. Manual crosscheck of references was performed. DATA EXTRACTION: We analyzed the bronchoscopy findings of individual patients in each study and their associated risk factors when available. RESULTS: We reviewed 11 articles, published between 1992 and 2016, including 885 patients (654 males, 237 females). Only 5 studies, including 455 patients, had sufficient data for meta-analysis. Our study revealed that the three most common bronchoscopy findings were subglottic stenosis, reflux changes, and broncho/tracheomalacia. Only 8.7% of patients were noted to have clinically significant findings on bronchoscopy. Meta analysis showed an association between significant bronchoscopy findings and History of Intubation [OR = 5.17, 95% CI 2.65-10.09], Inpatient Consultation [OR = 4.01, 95% CI 1.44-11.20], Age < 3 [OR = 3.22, 95% 1.66-6.27], Age < 1 [OR = 2.86, 95% CI 1.28-6.40], and Prematurity [OR = 2.90, 95% CI 1.39-6.06]. Our study found a high incidence of a History of GERD (20%) and Asthma/Allergies (35%) among patients with recurrent croup, but these variables did not reach statistical significance in patients with significant bronchoscopy findings ([OR = 1.62, 95% CI 0.79-3.30], [OR = 0.57, 95% CI 0.30-1.08] respectively). CONCLUSION: The risk factors most associated with clinically significant bronchoscopy findings in recurrent croup are Intubation, Inpatient Consultation, Age < 3, Age <1, and Prematurity. A History of GERD and Asthma/Allergy, though highly prevalent in recurrent croup patients, were not statistically associated with significant bronchoscopy findings. RELEVANCE: The results should guide physicians in selecting which recurrent croup patients are most at risk for significant findings and thus may warrant bronchoscopy.


Subject(s)
Bronchomalacia/diagnostic imaging , Bronchoscopy , Croup/etiology , Gastroesophageal Reflux/diagnostic imaging , Laryngostenosis/diagnostic imaging , Tracheomalacia/diagnostic imaging , Age Factors , Bronchomalacia/complications , Child, Preschool , Croup/epidemiology , Gastroesophageal Reflux/complications , Humans , Infant , Intubation, Intratracheal , Laryngostenosis/complications , Premature Birth/epidemiology , Recurrence , Referral and Consultation , Risk Factors , Tracheomalacia/complications
3.
J Neurosurg ; 124(3): 647-56, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26473788

ABSTRACT

OBJECTIVE: This article introduces a classification scheme for extensive traumatic anterior skull base fracture to help stratify surgical treatment options. The authors describe their multilayer repair technique for cerebrospinal fluid (CSF) leak resulting from extensive anterior skull base fracture using a combination of laterally pediculated temporalis fascial-pericranial, nasoseptal-pericranial, and anterior pericranial flaps. METHODS: Retrospective chart review identified patients treated surgically between January 2004 and May 2014 for anterior skull base fractures with CSF fistulas. All patients were treated with bifrontal craniotomy and received pedicled tissue flaps. Cases were classified according to the extent of fracture: Class I (frontal bone/sinus involvement only); Class II (extent of involvement to ethmoid cribriform plate); and Class III (extent of involvement to sphenoid bone/sinus). Surgical repair techniques were tailored to the types of fractures. Patients were assessed for CSF leak at follow-up. The Fisher exact test was applied to investigate whether the repair techniques were associated with persistent postoperative CSF leak. RESULTS: Forty-three patients were identified in this series. Thirty-seven (86%) were male. The patients' mean age was 33 years (range 11-79 years). The mean overall length of follow-up was 14 months (range 5-45 months). Six fractures were classified as Class I, 8 as Class II, and 29 as Class III. The anterior pericranial flap alone was used in 33 patients (77%). Multiple flaps were used in 10 patients (3 salvage) (28%)--1 with Class II and 9 with Class III fractures. Five (17%) of the 30 patients with Class II or III fractures who received only a single anterior pericranial flap had persistent CSF leak (p < 0.31). No CSF leak was found in patients who received multiple flaps. Although postoperative CSF leak occurred only in high-grade fractures with single anterior flap repair, this finding was not significant. CONCLUSIONS: Extensive anterior skull base fractures often require aggressive treatment to provide the greatest long-term functional and cosmetic benefits. Several vascularized tissue flaps can be used, either alone or in combination. Vascularized flaps are an ideal substrate for cranial base repair. Dual and triple flap techniques that combine the use of various anterior, lateral, and nasoseptal flaps allow for a comprehensive arsenal in multilayered skull base repair and salvage therapy for extensive and severe fractures.


Subject(s)
Cerebrospinal Fluid Leak/surgery , Plastic Surgery Procedures , Skull Base/injuries , Skull Fractures/surgery , Surgical Flaps , Adolescent , Adult , Aged , Cerebrospinal Fluid Leak/etiology , Child , Female , Humans , Male , Middle Aged , Patient Selection , Retrospective Studies , Skull Fractures/complications , Treatment Outcome , Young Adult
4.
Cleft Palate Craniofac J ; 53(2): 245-8, 2016 03.
Article in English | MEDLINE | ID: mdl-26171569

ABSTRACT

A case report of a congenital, lingual, salivary gland choristoma with bifid tongue and cleft palate is presented. The patient was born with airway obstruction in supine positioning. Laryngoscopy revealed a midline tongue mass that extended into the hypopharyx and pathological examination showed a congenital ectopic salivary gland. The bifid tongue was repaired at the time of surgical excision. Literature review revealed nine additional cases of congenital lingual mass, bifid tongue, and cleft palate. The most common tongue mass reported was hamartoma (40%), but the differential diagnoses include hamartoma, teratoma, and salivary choristoma.


Subject(s)
Choristoma/diagnosis , Cleft Palate/complications , Salivary Glands , Tongue Diseases/diagnosis , Tongue/abnormalities , Abnormalities, Multiple , Diagnosis, Differential , Female , Humans , Infant, Newborn , Laryngoscopy , Tongue/surgery , Tongue Diseases/surgery
5.
J Okla State Med Assoc ; 109(9): 441-5, 2016 09.
Article in English | MEDLINE | ID: mdl-29280606

ABSTRACT

OBJECTIVE: To assess patient opinion on the Patient Protection and Affordable Care Act (PPACA) in an Otolaryngology practice and the factors that influence those opinions. STUDY DESIGN: Observational study. METHODS: An anonymous survey assessing patient opinion on the PPACA, demographic information, political affiliation, medical diagnosis, and insurance status was distributed to patients in three separate Otolaryngology clinics (General, cancer, and Low-income/Indigent) from April to June 2014. A total of 300 surveys were distributed and 207 were used for final analysis. The primary study outcome measures were patient opinion of the PPACA and statistically significant variables affecting that opinion. The association of Support for the PPACA and variables were tested using the Chi-square test. RESULTS: The only variables that showed a significant association with support for the PPACA were Political Party (p<0.0001) and Ethnicity (p=0.0050). Specifically, a higher proportion of Democrats support the PPACA than Republicans and a higher proportion of African Americans and Hispanic/Latinos support the PPACA than Whites and Native Americans. CONCLUSION: Our survey of current Otolaryngology patients mirrors national findings of the division between Republicans and Democrats in their attitudes towards the Affordable Care Act. Political party appears to be the most significant factor in shaping patient opinion on this controversial subject regardless of insurance status or cancer diagnosis and a higher proportion of African Americans and Hispanic/Latinos support the PPACA than Whites and Native Americans. LEVEL OF EVIDENCE: IV.


Subject(s)
Attitude to Health , Ethnicity , Otolaryngology , Outpatients , Patient Protection and Affordable Care Act , Politics , Public Opinion , Black or African American , Female , Hispanic or Latino , Humans , Indians, North American , Insurance Coverage , Insurance, Health , Male , Surveys and Questionnaires , White People
6.
JAMA Otolaryngol Head Neck Surg ; 139(6): 574-8, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23680971

ABSTRACT

IMPORTANCE: If not adequately cleaned, rigid nasal endoscopes (RNEs) have the potential to cause iatrogenic cross-contamination. OBJECTIVE: To test the efficacy of various disinfection methods in reducing bacterial load on RNEs in vitro. DESIGN AND SETTING: In vitro model. INTERVENTIONS: Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, and Haemophilus influenzae contamination was separately induced on RNEs in vitro. Two experimental sets were completed. The RNEs were disinfected using the following protocols: 30-second scrub with antimicrobial soap (ABS) and water, 30-second scrub with 70% isopropyl alcohol (IA), 30-second scrub with ABS followed by 30-second scrub with IA, 30-second scrub with germicidal cloth, isolated 5-minute soak in an enzymatic soap solution, 5- and 10-minute soaks in ortho-phthalaldehyde, 0.55%, solution (Cidex OPA), and isolated 30-second rinse with tap water, all with 30-second precleaning and postcleaning rinses with tap water. Two sets of experiments (experiment sets A and B) were carried out with a 30-second tap water rinse after inoculation of each RNE. This was followed by immediate cleaning in set A and a 1-hour air-dry delay in set B. Otherwise there were no differences in the disinfection protocols between sets for each method noted. MAIN OUTCOMES AND MEASURES: Effectiveness of various disinfection protocols in cleaning rigid nasal endoscopes experimentally inoculated with bacteria commonly found in the upper aerodigestive tract. Positive cultures following disinfection indicated ineffective or incomplete disinfection. RESULTS: Most cleaning methods were effective in eliminating S aureus, S pneumoniae, and H influenzae from the scopes following experimental contamination. Continued growth of P aeruginosa was found after all of the disinfection trials in experiment set A with the exception of a 10-minute immersion in Cidex OPA, and in set B except for the 10-minute Cidex OPA immersion and ABS plus IA trials. CONCLUSIONS AND RELEVANCE: Most cleaning methods used in our trials appear to properly disinfect RNEs after in vitro inoculation with S aureus, S pneumoniae, and H influenzae. However, it appears that disinfectants may be less effective in cleaning rigid scopes experimentally inoculated with P aeruginosa. There is a paucity of published data regarding cross-contamination during rigid nasal endoscopy, and these results should guide future studies and to some extent practice to avoid iatrogenic spread of contamination.


Subject(s)
Cross Infection/prevention & control , Disinfectants/pharmacology , Disinfection/methods , Endoscopes/microbiology , Equipment Contamination/prevention & control , Glutaral/pharmacology , Haemophilus influenzae/growth & development , Pseudomonas aeruginosa/growth & development , Soaps/pharmacology , Staphylococcus aureus/growth & development , Streptococcus pneumoniae/growth & development , o-Phthalaldehyde/pharmacology , Cross Infection/microbiology , Humans , In Vitro Techniques , Nose/microbiology
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