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2.
Female Pelvic Med Reconstr Surg ; 27(8): 507-513, 2021 08 01.
Article in English | MEDLINE | ID: mdl-34397607

ABSTRACT

OBJECTIVES: The objectives of this study were to describe trajectories of pelvic floor symptoms and support from the third trimester to 1 year postpartum in primiparous women after vaginal delivery and to explore factors associated with their resolution between 8 weeks postpartum and 1 year postpartum. METHODS: Five hundred ninety-seven nulliparous women 18 years or older who gave birth vaginally at term completed the Epidemiology of Prolapse and Incontinence Questionnaire and the Pelvic Organ Prolapse Quantification examination at the third trimester, 8 weeks postpartum, and 1 year postpartum. RESULTS: At 1 year postpartum, 41%, 32%, and 23% of participants reported stress urinary incontinence, nocturia, and flatus incontinence, respectively, and 9% demonstrated maximal vaginal descent (MVD) ≥ 0 cm. For more common symptoms, incidence rates between the third trimester and 8 weeks postpartum ranged from 6% for urinary frequency to 22% for difficult bowel movements, and resolution rates between 8 weeks postpartum and 1 year postpartum ranged from 23% for stress urinary incontinence to 73% for pain. Between the third trimester and 8 weeks postpartum, 13% demonstrated de novo MVD ≥ 0 cm. For most symptoms, the presence of the same symptom before delivery decreased the probability of resolution between 8 weeks postpartum and 1 year. However, the sensitivities of predelivery vaginal bulge and MVD of 0 cm or greater for those outcomes at 1 year postpartum was overall low (10-12%). CONCLUSIONS: One year postpartum, urinary and bowel symptoms are common in primiparous women who gave birth vaginally. A substantial portion of this burden is represented by symptoms present before delivery, while most of the prevalence of worse anatomic support is accounted for by de novo changes after delivery.


Subject(s)
Delivery, Obstetric/adverse effects , Disease Progression , Pelvic Floor Disorders/epidemiology , Adult , Delivery, Obstetric/statistics & numerical data , Female , Humans , Longitudinal Studies , Postpartum Period , Pregnancy , Pregnancy Complications/epidemiology , Pregnancy Trimester, Third , Surveys and Questionnaires
3.
Am J Obstet Gynecol ; 225(2): 169.e1-169.e16, 2021 08.
Article in English | MEDLINE | ID: mdl-33705749

ABSTRACT

BACKGROUND: Anatomic terminology in both written and verbal forms has been shown to be inaccurate and imprecise. OBJECTIVE: Here, we aimed to (1) review published anatomic terminology as it relates to the posterior female pelvis, posterior vagina, and vulva; (2) compare these terms to "Terminologia Anatomica," the internationally standardized terminology; and (3) compile standardized anatomic terms for improved communication and understanding. STUDY DESIGN: From inception of the study to April 6, 2018, MEDLINE database was used to search for 40 terms relevant to the posterior female pelvis and vulvar anatomy. Furthermore, 11 investigators reviewed identified abstracts and selected those reporting on posterior female pelvic and vulvar anatomy for full-text review. In addition, 11 textbook chapters were included in the study. Definitions of all pertinent anatomic terms were extracted for review. RESULTS: Overall, 486 anatomic terms were identified describing the vulva and posterior female pelvic anatomy, including the posterior vagina. "Terminologia Anatomica" has previously accepted 186 of these terms. Based on this literature review, we proposed the adoption of 11 new standardized anatomic terms, including 6 regional terms (anal sphincter complex, anorectum, genital-crural fold, interlabial sulcus, posterior vaginal compartment, and sacrospinous-coccygeus complex), 4 structural terms (greater vestibular duct, anal cushions, nerve to the levator ani, and labial fat pad), and 1 anatomic space (deep postanal space). In addition, the currently accepted term rectovaginal fascia or septum was identified as controversial and requires further research and definition before continued acceptance or rejection in medical communication. CONCLUSION: This study highlighted the variability in the anatomic nomenclature used in describing the posterior female pelvis and vulva. Therefore, we recommended the use of standardized terminology to improve communication and education across medical and anatomic disciplines.


Subject(s)
Pelvic Floor/anatomy & histology , Terminology as Topic , Vagina/anatomy & histology , Vulva/anatomy & histology , Blood Vessels/anatomy & histology , Fascia/anatomy & histology , Female , Humans , Pelvis/anatomy & histology , Peripheral Nerves/anatomy & histology , Sacrococcygeal Region
4.
Am J Obstet Gynecol ; 223(1): 105.e1-105.e8, 2020 07.
Article in English | MEDLINE | ID: mdl-31954153

ABSTRACT

BACKGROUND: Family history of pelvic organ prolapse among first-degree relatives is an established risk factor for pelvic organ prolapse; however, consideration of the constellation of family history that extends to distant relationships allows for more accurate determination of risk and may improve pelvic organ prolapse risk prediction estimates. OBJECTIVE: The purpose of this study was to assess risk for pelvic organ prolapse treatment based on varying family histories of pelvic organ prolapse and included number and types of affected relatives, ages of relatives at pelvic organ prolapse treatment, and whether the family history is of maternal or paternal origin. STUDY DESIGN: This was a retrospective, population-based study that involved the Utah Population Database, which is a population resource that includes extensive genealogy information linked to medical records. The study population included 453,522 total women: 4628 women with a diagnosis of treated (surgical or pessary) pelvic organ prolapse and their 15,530 first-degree relatives; 33,782 second-degree relatives, and 66,469 third-degree relatives. We estimated relative risk of treated pelvic organ prolapse based on specific family history constellations. RESULTS: Relative risk estimates increased with a family history of increasing numbers of treated first-degree relatives with pelvic organ prolapse (first-degree relatives, ≥1 [relative risk, 2.36; 95% confidence interval, 2.15-2.58], first-degree relatives, ≥2 [relative risk, 3.79; 95% confidence interval, 2.65-5.24], and first-degree relatives, ≥3 [relative risk, 6.26; 95% confidence interval, 1.29-18.30]). Having a family history of ≥3 affected third-degree relatives (eg, first cousins) and no affected first- or second-degree relatives was similar in risk to having 1 affected first-degree relative. Relative risk estimates decreased with increasing age of treatment for first-degree family members. Risks in individuals with a positive maternal family history for pelvic organ prolapse were consistently higher than risks in individuals with equivalent paternal family history, but paternal inheritance still played a role. Approximately 4% of the total studied female population was found to have a >2-fold risk of being treated for pelvic organ prolapse and is considered high-risk based on their family history. CONCLUSION: We provide estimates for treated pelvic organ prolapse based on an extensive family history of pelvic organ prolapse using a large population-based sample. Risk for treated pelvic organ prolapse increased with increasing numbers of affected close and distant female relatives, earlier age of pelvic organ prolapse treatment in relatives, and maternal inheritance. These risk estimates may be useful for genetic studies and investigation of risk reduction strategies in those at highest risk for pelvic organ prolapse.


Subject(s)
Pelvic Organ Prolapse/epidemiology , Pelvic Organ Prolapse/therapy , Adult , Aged , Aged, 80 and over , Female , Humans , Medical History Taking , Middle Aged , Pelvic Organ Prolapse/genetics , Retrospective Studies , Risk Assessment , Risk Factors
5.
Female Pelvic Med Reconstr Surg ; 26(11): 655-663, 2020 11.
Article in English | MEDLINE | ID: mdl-30570501

ABSTRACT

OBJECTIVE: The aim of this study was to determine the safety and efficacy of methods for intraoperative evaluation of urinary tract injury during pelvic surgery. METHODS: PubMed, EMBASE, CINAHL, Web of Science, Scopus, ProQuest, the Cochrane Library, and Clinicaltrials.gov were searched from 1947 to February 2018. Articles or abstracts describing the routine evaluation of urinary tract injuries during pelvic surgery in adults were included, surgical indications of urinary tract anomaly, stones, or malignancy were excluded. There were no restrictions on study design or language. Outcomes included injuries diagnosed intraoperatively, delayed diagnoses, adverse effects, subjective assessments, time to use, and cost. Data were extracted in duplicate at an individual-participant level. Prevalence of injuries, sensitivity, specificity, and predictive values of each diagnostic method were calculated. A combination of generalized linear models and a Bayesian approach were used to separately pool diagnostic accuracy measures. RESULTS: There were 5303 titles, 527 abstracts, and 164 full-text articles assessed for eligibility; 69 articles were analyzed. Diagnostic methods retrieved were cystoscopy using saline, dextrose or unspecified distention media, oral phenazopyridine and vitamin B, intravenous (IV) methylene blue, IV sodium fluorescein, IV indigo carmine, prophylactic retrograde ureteral stents, and transabdominal Doppler ultrasound. Prevalence of urinary tract injury ranged from 0.3% to 2.8%. Sensitivity ranged 63% to 91%, and specificity, 99.7% to 100%, with no significant differences suggested between methods. CONCLUSIONS: All evaluable methods of intraoperative urinary tract assessment during pelvic surgery are safe and effective with specificity of greater than 99% and low rates of complications. Larger, more rigorous studies are required to evaluate the diagnostic accuracy of some newer methods.


Subject(s)
Intraoperative Complications/diagnosis , Lower Urinary Tract Symptoms/diagnosis , Urinary Tract/injuries , Urologic Diseases/diagnosis , Cystoscopy/methods , Humans , Iatrogenic Disease , Intraoperative Complications/etiology , Lower Urinary Tract Symptoms/etiology , Urologic Diseases/etiology
6.
Female Pelvic Med Reconstr Surg ; 26(1): 61-66, 2020.
Article in English | MEDLINE | ID: mdl-29727372

ABSTRACT

OBJECTIVE: The aim oft his study was to compare the effects of 10 common exercises to traditional pelvic floor muscle (PFM) contractions (Kegel) on levator hiatus (LH) area and PFM length and strength. METHODS: This is a cross-sectional study of 15 healthy postpartum women. Ten exercises were studied. These were common variations of leg, core, and back exercises used in yoga, Pilates, strength training, and physical therapy. Each participant performed all 10 exercises at a single visit in 2 examination settings: transperineal ultrasound and perineometry. Ultrasound measured the LH area and PFM length, and perineometry measured the muscle strength (peak squeeze pressure). RESULTS: Kegel generates an increase in squeeze pressure (24.3 cm H2O), shortens the muscles (-0.46 cm) and narrows the LH (-0.13 cm). The bird-dog and plank exercises were not different from Kegel in any measurement. While the leg-lift ultrasound dimensions are similar to Kegel, leg lifts generated peak squeeze pressures stronger than any other exercise (including Kegel). Whereas ultrasound dimensions were similar to Kegel, tucked and untucked squats and thigh adductions generated weaker contractions than Kegel. While crunch generated a squeeze pressure similar to Kegel, the ultrasound dimensions showed a significantly wider LH and longer muscle than Kegel. Bridge, clam, and plié exercises affected the PFMs differently than Kegel in all measures. CONCLUSIONS: Bird-dog, plank, and leg-lift exercises should be evaluated as alternative exercises to Kegel as they affect PFM strength and length and LH area similarly to Kegel, and leg lifts generate a stronger contraction than Kegel.


Subject(s)
Exercise/physiology , Muscle Contraction/physiology , Muscle Strength/physiology , Pelvic Floor/physiology , Adult , Cross-Sectional Studies , Female , Humans , Pelvic Floor/diagnostic imaging , Pelvic Floor Disorders/prevention & control
7.
Am J Obstet Gynecol ; 222(3): 204-218, 2020 03.
Article in English | MEDLINE | ID: mdl-31805273

ABSTRACT

The objectives of this study were to review the published literature and selected textbooks, to compare existing usage to that in Terminologia Anatomica, and to compile standardized anatomic nomenclature for the apical structures of the female pelvis. MEDLINE was searched from inception until May 30, 2017, based on 33 search terms generated by group consensus. Resulting abstracts were screened by 11 reviewers to identify pertinent studies reporting on apical female pelvic anatomy. Following additional focused screening for rarer terms and selective representative random sampling of the literature for common terms, accepted full-text manuscripts and relevant textbook chapters were extracted for anatomic terms related to apical structures. From an initial total of 55,448 abstracts, 193 eligible studies were identified for extraction, to which 14 chapters from 9 textbooks were added. In all, 293 separate structural terms were identified, of which 184 had Terminologia Anatomica-accepted terms. Inclusion of several widely used regional terms (vaginal apex, adnexa, cervico-vaginal junction, uretero-vesical junction, and apical segment), structural terms (vesicouterine ligament, paracolpium, mesoteres, mesoureter, ovarian venous plexus, and artery to the round ligament) and spaces (vesicocervical, vesicovaginal, presacral, and pararectal) not included in Terminologia Anatomica is proposed. Furthermore, 2 controversial terms (lower uterine segment and supravaginal septum) were identified that require additional research to support or refute continued use in medical communication. This study confirms and identifies inconsistencies and gaps in the nomenclature of apical structures of the female pelvis. Standardized terminology should be used when describing apical female pelvic structures to facilitate communication and to promote consistency among multiple academic, clinical, and surgical disciplines.


Subject(s)
Genitalia, Female/anatomy & histology , Pelvis/anatomy & histology , Terminology as Topic , Urinary Tract/anatomy & histology , Arteries/anatomy & histology , Female , Humans , Ligaments/anatomy & histology , Veins/anatomy & histology
8.
Am J Obstet Gynecol ; 219(1): 26-39, 2018 07.
Article in English | MEDLINE | ID: mdl-29630884

ABSTRACT

BACKGROUND: The use of imprecise and inaccurate terms leads to confusion amongst anatomists and medical professionals. OBJECTIVE: We sought to create recommended standardized terminology to describe anatomic structures of the anterior female pelvis based on a structured review of published literature and selected text books. STUDY DESIGN: We searched MEDLINE from its inception until May 2, 2016, using 11 medical subject heading terms to identify studies reporting on anterior female pelvic anatomy; any study type published in English was accepted. Nine textbooks were also included. We screened 12,264 abstracts, identifying 200 eligible studies along with 13 textbook chapters from which we extracted all pertinent anatomic terms. RESULTS: In all, 67 unique structures in the anterior female pelvis were identified. A total of 59 of these have been previously recognized with accepted terms in Terminologia Anatomica, the international standard on anatomical terminology. We also identified and propose the adoption of 4 anatomic regional terms (lateral vaginal wall, pelvic sidewall, pelvic bones, and anterior compartment), and 2 structural terms not included in Terminologia Anatomica (vaginal sulcus and levator hiatus). In addition, we identified 2 controversial terms (pubourethral ligament and Grafenberg spot) that require additional research and consensus from the greater medical and scientific community prior to adoption or rejection of these terms. CONCLUSION: We propose standardized terminology that should be used when discussing anatomic structures in the anterior female pelvis to help improve communication among researchers, clinicians, and surgeons.


Subject(s)
Ligaments/anatomy & histology , Pelvic Bones/anatomy & histology , Pelvis/anatomy & histology , Terminology as Topic , Vagina/anatomy & histology , Female , Humans , Reference Standards
9.
Int Urogynecol J ; 29(2): 285-290, 2018 02.
Article in English | MEDLINE | ID: mdl-28580496

ABSTRACT

INTRODUCTION AND HYPOTHESIS: Limited evidence guides operative technique in primary midurethral sling (MUS) lysis or excision at the time of repeat sling placement for persistent or recurrent stress urinary incontinence (SUI). Our objective is to compare subjective improvement in patients undergoing repeat MUS placement with and without concurrent primary sling lysis or removal. METHODS: This was a retrospective cohort study with a prospective survey of patients who underwent two MUS placements for SUI at a single institution from January 1996 to December 2015. After patient identification, the electronic record was queried for demographic and perioperative data. Subjects then completed the Urogenital Distress Index, (UDI-6), Incontinence Severity Index (ISI), and the Incontinence Impact Questionnaire (IIQ-7). Subjects were also asked if they would choose to undergo repeat MUS surgery again. RESULTS: Sixty-one patients were included. 17 out of 61 (28%) underwent concomitant primary sling lysis or excision, and 44 out of 61 (72%) did not. Fifty-seven percent (n = 35) completed the survey. Of the respondents, the median ISI score was 4 (1-8), with no difference between groups; 14 out of 35 (40%) reported the presence of bothersome urge incontinence, 11 out of 35 (31%) reported bothersome stress urinary incontinence, and 8 out of 35 (23%) reported symptoms of voiding dysfunction, with no difference between groups. 57% of patients (20 out of 35) would undergo repeat MUS placement again. CONCLUSIONS: In a small cohort, concurrent excision of the primary sling at the time of repeat MUS did not improve subjective outcomes. Many patients reported urinary urgency and voiding symptoms, and only about half of patients would choose to undergo the surgery again if given the choice.


Subject(s)
Patient Satisfaction , Reoperation/psychology , Suburethral Slings , Urinary Incontinence, Stress/surgery , Urologic Surgical Procedures/psychology , Aged , Female , Humans , Middle Aged , Prospective Studies , Recurrence , Reoperation/methods , Retrospective Studies , Severity of Illness Index , Surveys and Questionnaires , Treatment Outcome , Urinary Incontinence, Stress/psychology , Urologic Surgical Procedures/methods
10.
J Minim Invasive Gynecol ; 24(3): 344, 2017.
Article in English | MEDLINE | ID: mdl-27553183

ABSTRACT

STUDY OBJECTIVE: To describe a technique for performing laparoscopic Burch colposuspension using a 3-trocar system. DESIGN: This educational video provides step-by-step instructions for performing a laparoscopic Burch colposuspension. This study was exempt from institutional review board approval. SETTING: Midurethral slings are an effective surgical treatment for women with stress urinary incontinence, but not all patients are candidates for, or desire, vaginal mesh. For stress incontinence, nonmesh surgical procedures include pubovaginal fascial slings and retropubic Burch colposuspension. Colposuspension may be performed via an open or laparoscopic approach. As with other minimally invasive surgeries, laparoscopic colposuspension has decreased blood loss, pain, and length of stay with equivalent outcomes at 2 years compared with open procedures. This video describes a technique for performing laparoscopic Burch colposuspension using a 3-trocar system. INTERVENTIONS: A laparoscopic Burch colposuspension is described using a 3-trocar system. Detailed step-by-step instructions are given, along with visualization of pertinent anatomy. Supplies needed for this procedure include a 0-degree, 5-mm laparoscope; two 5-mm trocars, 1 to be placed in the umbilicus and 1 in the left lower quadrant; one 5/12-mm trocar to be placed in the right lower quadrant for passing needles; a closed knot pusher; laparoscopic scissors; and 2 needle drivers. This technique assumes that the primary surgeon (located on the patient's left) is right-handed and that both surgeons can suture and tie knots laparoscopically. Tips are highlighted to ensure safety and ensure successful completion of the procedure. CONCLUSION: Laparoscopic Burch colposuspension offers a nonmesh-based repair for women with stress urinary incontinence using a minimally invasive approach. It is a reasonable alternative to offer patients with stress urinary incontinence who do not desire repair using vaginal mesh.


Subject(s)
Gynecologic Surgical Procedures , Urinary Incontinence, Stress/surgery , Urologic Surgical Procedures , Adult , Female , Gynecologic Surgical Procedures/instrumentation , Gynecologic Surgical Procedures/methods , Humans , Laparoscopy/methods , Middle Aged , Surgical Instruments , Sutures , Treatment Outcome , Urologic Surgical Procedures/instrumentation , Urologic Surgical Procedures/methods , Vagina/surgery
11.
Int Urogynecol J ; 27(10): 1601-3, 2016 Oct.
Article in English | MEDLINE | ID: mdl-27139717

ABSTRACT

INTRODUCTION: Urethral prolapse is a rare condition that results in the eversion of the urethral mucosa through the distal urethra. Management is divided into two categories: conservative and surgical treatment. METHODS: We present a case of urethral prolapse with severe symptoms that were minimally responsive to topical estrogen. Surgical excision was achieved with resection of the redundant urethral mucosa. RESULTS: This video highlights surgical techniques that can be used for the excision of urethral prolapse. CONCLUSIONS: The management of urethral prolapse should be individualized based on symptom severity, anatomical compromise, and surgical morbidity. Surgical management should be considered in cases of vascular compromise or failed medical management.


Subject(s)
Urethral Diseases/surgery , Acute Disease , Administration, Topical , Conservative Treatment , Estrogens/administration & dosage , Female , Humans , Middle Aged , Postoperative Complications , Prolapse , Severity of Illness Index , Urinary Incontinence
12.
Obstet Gynecol ; 127(2): 330-40, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26942362

ABSTRACT

OBJECTIVE: To construct and validate models that predict a patient's risk of developing stress and urgency urinary incontinence and adverse events 12 months after sling surgery. METHODS: This was a secondary analysis of four randomized trials. Twenty-five candidate predictors (patient characteristics and urodynamic variables) were identified from the National Institute of Diabetes and Digestive and Kidney Diseases Trial of Mid-Urethral Slings (N=597). Multiple logistic models were fit to predict four different outcomes: 1) bothersome stress urinary incontinence; 2) a positive stress test; 3) bothersome urgency urinary incontinence; and 4) any adverse event up to 12 months after sling surgery. Model discrimination was measured using a concordance index. Each model's concordance index was internally validated using 1,000 bootstrap samples and calibration curves were plotted. Final models were externally validated on a separate data set (n=902) from a combination of three different multicenter randomized trials. RESULTS: Four best models discriminated on internal validation between women with bothersome stress urinary incontinence (concordance index 0.728, 95% confidence interval [CI] 0.683-0.773), a positive stress test (concordance index 0.712, 95% CI 0.669-0.758), bothersome urgency urinary incontinence (concordance index 0.722, 95% CI 0.680-0.764), and any adverse event (concordance index 0.640, 95% CI 0.595-0.681) after sling surgery. Each model's concordance index was reduced as expected when important variables were removed for external validation, but model discrimination remained stable with bothersome stress urinary incontinence (concordance index 0.548), a positive stress test (concordance index 0.656), bothersome urgency urinary incontinence (concordance index 0.621), and any adverse event (concordance index 0.567). Predicted probabilities are closest to actual probabilities when predictions are less than 50%. CONCLUSION: Four best and modified models discriminate between women who will and will not develop urinary incontinence and adverse events 12 months after midurethral sling surgery 64-73% and 55-66% of the time, respectively.


Subject(s)
Suburethral Slings/adverse effects , Urinary Incontinence, Stress/etiology , Urinary Incontinence, Urge/etiology , Aged , Female , Follow-Up Studies , Humans , Incidence , Middle Aged , Ohio , Predictive Value of Tests , Randomized Controlled Trials as Topic , Reproducibility of Results , Risk Assessment , Time Factors , Treatment Outcome , Urinary Incontinence, Stress/epidemiology , Urinary Incontinence, Stress/physiopathology , Urinary Incontinence, Urge/epidemiology , Urinary Incontinence, Urge/physiopathology , Urodynamics/physiology
13.
Am J Obstet Gynecol ; 214(4): 501.e1-501.e6, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26529371

ABSTRACT

BACKGROUND: Colpocleisis, a vaginal obliterative procedure, offers women with symptomatic pelvic organ prolapse an effective, durable anatomic repair and is associated with high patient satisfaction rates. Historically, colpocleisis was reserved for the medically frail or elderly with the goal of limiting anesthetic exposure, decreasing operative time, and minimizing adverse events. Several colpocleisis and colpectomy procedures exist and limited evaluation has been performed comparing these differences in regards to perioperative adverse events. OBJECTIVE: The primary objective was to describe the overall rate of perioperative adverse events in patients undergoing colpocleisis. The secondary objective was to compare rates of adverse events between different colpocleisis procedures. STUDY DESIGN: This is a retrospective chart review of patients who underwent colpocleisis at a tertiary care center from January 2003 through December 2013. Subjects were identified by their Current Procedural Terminology (CPT) codes and categorized into 3 groups: (1) partial or complete vaginectomy/colpectomy (CPT 57106, 57110); (2) vaginal hysterectomy with total or partial colpectomy (CPT 58275, 58280); and (3) Le Fort colpocleisis (CPT 57120). Baseline demographics, perioperative data, and postoperative data were collected. Analysis of variance was used to describe perioperative and postoperative adverse events in all subjects and to compare outcomes among the 3 groups. RESULTS: In all, 245 subjects underwent colpocleisis during the study period. Mean age and body mass index were 78 (±7) years and 27.7 (±5.8) kg/m(2), respectively; 59.1% (140/245) of subjects had stage-4 prolapse. The most common adverse event was urinary tract infection occurring in 34.7% of subjects. Major adverse events were uncommon. There were no differences in event rates among the groups except for the following: patients undergoing concurrent vaginal hysterectomy had longer mean operative time (144 vs 108 vs 111 minutes, P = .0001), had higher estimated blood loss (253 vs 135 vs 146 mL, P = .0001), and were more likely to experience postoperative venous thromboembolism (4.6% vs 0% vs 0%, P = .01). After controlling for age, body mass index, medical comorbidities, estimated blood loss, and operative time, the risk of venous thromboembolism was no longer significant. CONCLUSION: The overall rate of major perioperative and postoperative adverse events in women undergoing colpocleisis is low; however, concomitant hysterectomy is associated with longer operative times and higher blood loss.


Subject(s)
Gynecologic Surgical Procedures/adverse effects , Hysterectomy/adverse effects , Pelvic Organ Prolapse/surgery , Aged , Blood Loss, Surgical , Cohort Studies , Female , Humans , Operative Time , Retrospective Studies , Urinary Tract Infections/etiology , Vagina/surgery , Venous Thromboembolism/etiology
14.
Curr Opin Obstet Gynecol ; 27(5): 373-9, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26308201

ABSTRACT

PURPOSE OF REVIEW: This article reviews the current literature regarding surgical repair of vaginal apical prolapse and discusses the risks and benefits of various surgical approaches. RECENT FINDINGS: Vaginal uterosacral ligament suspension has similar anatomic and subjective outcomes to sacrospinous ligament fixation at 1 year. Native tissue vaginal repairs offer decreased morbidity compared with mesh-augmented sacrocolpopexy; however, sacrocolpopexy has greater anatomic success. Minimally invasive sacrocolpopexy appears to be equivalent to open abdominal sacrocolpopexy. Native tissue repairs and transvaginal mesh kits support the vaginal apex with similar results; however, long-term follow-up is needed. Robotic and laparoscopic sacrocolpopexy are equally effective in restoring the vaginal apex. SUMMARY: Surgical restoration of the vaginal apex can be accomplished via a variety of approaches and techniques. When deciding on the proper surgical intervention, the surgeon must carefully calculate the risks and benefits of each procedure while incorporating the patient's individual medical and surgical risk factors. Lastly, a discussion regarding the patient's overall goals of care is paramount to the decision-making process.


Subject(s)
Gynecologic Surgical Procedures/methods , Pelvic Organ Prolapse/surgery , Vagina/surgery , Decision Making , Female , Humans , Patient Selection , Pelvic Organ Prolapse/physiopathology , Risk Assessment , Risk Factors , Surgical Mesh , Treatment Outcome , Vagina/pathology
15.
J Minim Invasive Gynecol ; 22(5): 889-91, 2015.
Article in English | MEDLINE | ID: mdl-25757813

ABSTRACT

Vulvar pruritus is typically associated with fungal, bacterial, and/or dermatological conditions that routinely resolve with the use of topical medications. Pruritus rarely becomes chronic in nature without a definable pathological diagnosis. However, when this occurs, management is difficult and has limited treatment options. Few cases have reported resolution of vulvar pain or discomfort with sacral neuromodulation implantation. We report a case in which a patient experienced chronic vulvar pruritus that was refractory to medical treatments and did not have a pathological diagnosis. A neurological etiology was suspected, and upon replacement of the patient's sacral neuromodulation device, complete resolution of the vulvar symptoms occurred.


Subject(s)
Electric Stimulation Therapy/adverse effects , Electrodes, Implanted/adverse effects , Pruritus Vulvae/physiopathology , Urinary Bladder, Neurogenic/surgery , Chronic Disease , Device Removal , Female , Humans , Lumbosacral Plexus , Middle Aged , Pruritus Vulvae/etiology , Treatment Outcome
16.
Int Urogynecol J ; 26(4): 591-5, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25377295

ABSTRACT

INTRODUCTION AND HYPOTHESIS: The objective of this study was to compare the histological characteristics of pathological specimens of excised midurethral sling mesh and surrounding vaginal tissue in patients who presented preoperatively with pain and/or exposure of mesh to patients who underwent mesh excision for voiding dysfunction without pain and/or erosion. METHODS: This is a retrospective case-control study of women who underwent excision of midurethral sling mesh between 2008 and 2013. Three groups were identified: (1) voiding dysfunction without pain or exposure (control group), (2) pain and/or mesh exposure, and (3) voiding dysfunction with pain and/or mesh exposure. All original pathological specimens were rereviewed by one pathologist blinded to indication for excision and the previous pathology report. Degree of inflammation and fibrosis were recorded based on a 4-point scale along with the presence of giant cell reaction. RESULTS: A total of 130 subjects met inclusion criteria: 60 (46.2 %) with voiding dysfunction only, 21 (16.2 %) with pain/erosion, and 49 (37.7 %) with both pain/exposure and voiding dysfunction. The voiding dysfunction only group was found to have significantly higher levels of inflammation, median grade 2 (1-3), compared to the other two groups with a p value of 0.007. There were no statistical differences in fibrosis and giant cell reaction between the three groups. CONCLUSIONS: Midurethral sling mesh excised for voiding dysfunction demonstrates elevated levels of inflammation compared to mesh that is excised for pain and/or exposure. The vaginal tissue fibrosis and giant cell reaction are similar in patients who undergo mesh excision for voiding dysfunction and pain, and/or mesh exposure.


Subject(s)
Pain/pathology , Suburethral Slings/adverse effects , Surgical Mesh/adverse effects , Urination Disorders/pathology , Vagina/pathology , Adult , Case-Control Studies , Device Removal , Female , Fibrosis/pathology , Giant Cells, Foreign-Body/pathology , Humans , Inflammation/pathology , Middle Aged , Pain/etiology , Retrospective Studies , Urination Disorders/etiology
17.
Female Pelvic Med Reconstr Surg ; 20(2): 113-5, 2014.
Article in English | MEDLINE | ID: mdl-24566217

ABSTRACT

BACKGROUND: Identification of occult malignancy after intra-abdominal morcellation at the time of robotic-assisted supracervical hysterectomy and cervicosacropexy for uterine prolapse may lead to challenging postoperative management and leads one to question the need for preoperative evaluation. CASES: We present 2 cases of occult endometrial carcinoma after robotic-assisted supracervical hysterectomy and cervicosacropexy with intra-abdominal uterine morcellation from January 2008 to December 2010. A total of 63 patients underwent the stated surgical procedure with 2 patients (3.17%) found to have abnormal uterine pathologic finding with International Federation of Gynecology and Obstetrics grade 1 endometrial adenocarcinoma. Both cases occurred in asymptomatic postmenopausal patients without risk factors for endometrial cancer, including no history of postmenopausal bleeding or hormone replacement therapy. Owing to intraoperative uterine morcellation and cervical retention, appropriate postoperative management was controversial and problematic. Each patient was referred to gynecologic oncology. To date, both patients are without evidence of residual disease. CONCLUSION: Owing to the risk of occult uterine pathologic finding and complicated postoperative management, preoperative endometrial assessment should be considered on all postmenopausal patients undergoing intra-abdominal uterine morcellation, regardless of risk factors.


Subject(s)
Endometrial Neoplasms/diagnosis , Gynecologic Surgical Procedures/methods , Incidental Findings , Pelvic Organ Prolapse/surgery , Aged , Female , Humans , Hysterectomy/methods , Middle Aged , Risk Factors , Robotics
18.
South Med J ; 105(5): 274-8, 2012 May.
Article in English | MEDLINE | ID: mdl-22561541

ABSTRACT

OBJECTIVE: To evaluate outcomes of robot-assisted sacrocolpopexy (RSCP) and sacrocervicopexy (RCSP). METHODS: We conducted a prospective study of women undergoing RSCP or RCSP between June 2008 and January 2010. RESULTS: A total of 85 cases (48 RSCP and 37 supracervical hysterectomy with concomitant RCSP) were performed: 33% (28/85) for stage II, 54% (46/85) for stage III, and 13% (11/85) for stage IV pelvic organ prolapse (POP). Six weeks postoperatively, 96% (80/83) had stage 0, 2.4% (2/83) had stage I, and 1.2% (1/83) had stage II POP (P < 0.001). Six months postoperatively, 77% (24/31) had stage 0, 6.5% (2/31) had stage I, and 16% (5/31) had stage II POP (P < 0.001). Mean surgical time, estimated blood loss, and length of hospital stay was 194 ± 54 minutes, 49 ± 48 cm, and 1.6 ± 0.72 days, respectively. There were 2 cases of mesh erosion (2.3%), both in the RSCP group. CONCLUSIONS: RSCP and RCSP are effective, efficient, and safe procedures.


Subject(s)
Pelvic Floor Disorders/surgery , Pelvic Floor/surgery , Pelvic Organ Prolapse/surgery , Pelvis/surgery , Robotics/methods , Female , Follow-Up Studies , Humans , Postoperative Complications , Prospective Studies , Surveys and Questionnaires , Treatment Outcome
19.
Int Urogynecol J ; 23(9): 1183-6, 2012 Sep.
Article in English | MEDLINE | ID: mdl-22527548

ABSTRACT

INTRODUCTION AND HYPOTHESIS: Our aim was to determine what effect access to robotic technology had on our approach to managing apical pelvic support defects. METHODS: This was a retrospective chart review of 187 pelvic floor reconstructive surgeries performed for the 18 months prior to (time period 1: January 2007 to July 2008) and following (time period 2: July 2009 to December 2009) the introduction of the robot. Chi-square was used to compare percentages, and analysis of variance (ANOVA) was used to compare demographic data among groups. RESULTS: Overall, 187 procedures were performed for apical prolapse during the study period: 61 in time period 1 and 126 in time period 2. Following the introduction of robotic technology, a significant change from vaginal to abdominal reconstruction occurred. Uterosacral ligament suspension declined from 67 % to 22 % (p < 0.0001), whereas sacrocolpopexy increased from 25 % (15/61) to 66 % (83/126) (p < 0.0001). The rate of abdominal sacrocolpopexy, however, declined from 25 % (15/61) to 2 % (2/126) over the two time periods (p < 0.0001). CONCLUSION: The introduction of robotic technology significantly affected the surgical procedure and mode of surgical access for repair of apical pelvic support defects.


Subject(s)
Gynecologic Surgical Procedures/trends , Minimally Invasive Surgical Procedures/trends , Pelvic Organ Prolapse/surgery , Robotics/trends , Abdomen/surgery , Adnexa Uteri/surgery , Adult , Aged , Analysis of Variance , Chi-Square Distribution , Female , Humans , Ligaments/surgery , Middle Aged , Retrospective Studies , Vagina/surgery
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