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1.
Nurs Educ Perspect ; 40(2): 110-112, 2019.
Article in English | MEDLINE | ID: mdl-30095733

ABSTRACT

Students in health care today are very different than those of past generations. Health care education requires both innovation and creativity to meet the changing needs of students. Soft skills such as leadership, communication, nursing informatics, technology, and professionalism can sometimes be lost in pursuit of scientific knowledge. The purpose of this descriptive pilot study was to evaluate the effectiveness of a product designed to assist in the development of soft skills in a bachelor of science in nursing curriculum. This research did not support the additive value of this particular product but recommended further research at other curricular levels.


Subject(s)
Education, Nursing, Baccalaureate , Students, Nursing , Curriculum , Humans , Leadership , Nursing Education Research , Pilot Projects , Students
2.
J Holist Nurs ; 35(4): 342-351, 2017 Dec.
Article in English | MEDLINE | ID: mdl-30208778

ABSTRACT

BACKGROUND: Pain following orthopedic surgery can be intense due to the nature of the surgical procedure. Pain is a multilevel phenomenon that includes physiological and psychosocial components. Interventions that address body, mind, and spirit are needed to provide holistic management of pain. Guided imagery is a mind-body intervention that can address all aspects of the patient's pain experience. PURPOSE: This integrative review, informed by Watson's theory of human caring, identifies evidence that either supports or refutes the use of guided imagery as a supplement to pharmaceutical pain management for postoperative orthopedic patients. METHOD: An integrative literature search was conducted. Twenty-two studies were identified as potentially relevant to this study. Nine of the articles met all inclusion criteria and were included in this study. RESULTS AND CONCLUSIONS: Based on the evidence reviewed, it is recommended that guided imagery be used as an adjunct for pain management in patients undergoing orthopedic surgery. However, additional research in this area is needed. Future research: Two topics for further research were identified. The first is a need to identify an optimal frequency of use of guided imagery. The second is to identify how to ensure patients are using the intervention as recommended.


Subject(s)
Biofeedback, Psychology/physiology , Imagery, Psychotherapy , Meditation/methods , Orthopedic Procedures/psychology , Pain Management/methods , Pain, Postoperative/prevention & control , Evidence-Based Practice , Humans , Imagery, Psychotherapy/methods , Meditation/psychology , Orthopedic Procedures/adverse effects , Orthopedic Procedures/rehabilitation , Pain Management/psychology , Randomized Controlled Trials as Topic , Treatment Outcome
3.
Nature ; 452(7190): 949-55, 2008 Apr 24.
Article in English | MEDLINE | ID: mdl-18362917

ABSTRACT

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell-cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.


Subject(s)
Genes, Insect/genetics , Genome, Insect/genetics , Tribolium/genetics , Animals , Base Composition , Body Patterning/genetics , Cytochrome P-450 Enzyme System/genetics , DNA Transposable Elements/genetics , Growth and Development/genetics , Humans , Insecticides/pharmacology , Neurotransmitter Agents/genetics , Oogenesis/genetics , Phylogeny , Proteome/genetics , RNA Interference , Receptors, G-Protein-Coupled/genetics , Receptors, Odorant/genetics , Repetitive Sequences, Nucleic Acid/genetics , Taste/genetics , Telomere/genetics , Tribolium/classification , Tribolium/embryology , Tribolium/physiology , Vision, Ocular/genetics
4.
ANS Adv Nurs Sci ; 30(2): 175-88, 2007.
Article in English | MEDLINE | ID: mdl-17510574

ABSTRACT

BACKGROUND: Women with urinary incontinence (UI) report that the disease negatively impacts their quality of life but, paradoxically, under-report symptoms. METHOD: A predictive model using Orem's self-care deficit theory was developed exploring the effect of body experience on self-care agency to manage UI. A sample of postmenopausal women was drawn from a larger trial. Structural equation modeling was used to test the proposed model. RESULTS: Minor modification of the model produced a well-fitting model (chi(9) = 3.20, P = .96, n = 235). Results supported the positive effect of nursing agency on self-care agency. CONCLUSION: Group education about UI may increase self-care agency in postmenopausal women.


Subject(s)
Health Knowledge, Attitudes, Practice , Self Care/psychology , Urinary Incontinence/nursing , Aged , Aged, 80 and over , Body Image , Cross-Sectional Studies , Emotions , Female , Health Surveys , Humans , Longitudinal Studies , Middle Aged , Models, Theoretical , Self Care/methods , Urinary Incontinence/psychology
5.
Health Educ Behav ; 34(6): 942-52, 2007 Dec.
Article in English | MEDLINE | ID: mdl-17456856

ABSTRACT

Past research suggests a positive correlation between self-efficacy (SE) and adherence to behavioral interventions. Less is known about SE and adherence in behavioral programs that are preventive in nature and specific to urinary incontinence (UI). Using treatment-group data from a previously reported randomized controlled trial, the authors assess the role of SE in predicting adherence to pelvic-floor muscle training (PFMT) for UI prevention in a sample of postmenopausal women. Results indicate that at 12 months follow-up, nearly 70% of participants reported medium or high adherence, performing the recommended PFMT regimen 2 to 3 times per week or more. Summary scores of both Task SE, beta = .25, SE (beta) = .08, p < .01, and Regulatory SE, beta = .43, SE (beta) = .06, p < .0001, predict adherence. Also, the authors found a modest decline in self-efficacy scores over time. These findings highlight the importance of SE in sustained behavioral change.


Subject(s)
Exercise Therapy/statistics & numerical data , Muscle Contraction/physiology , Patient Compliance/psychology , Pelvic Floor/physiology , Self Efficacy , Urinary Incontinence/prevention & control , Aged , Aged, 80 and over , Female , Forecasting , Health Behavior , Humans , Middle Aged , Regression Analysis
6.
Science ; 316(5822): 222-34, 2007 Apr 13.
Article in English | MEDLINE | ID: mdl-17431167

ABSTRACT

The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.


Subject(s)
Evolution, Molecular , Genome , Macaca mulatta/genetics , Animals , Biomedical Research , Female , Gene Duplication , Gene Rearrangement , Genetic Diseases, Inborn , Genetic Variation , Humans , Male , Multigene Family , Mutation , Pan troglodytes/genetics , Sequence Analysis, DNA , Species Specificity
7.
West J Nurs Res ; 29(1): 36-56; discussion 57-64, 2007 Feb.
Article in English | MEDLINE | ID: mdl-17228060

ABSTRACT

This exploratory study assesses factors predicting adherence to a behavioral intervention to prevent urinary incontinence. Community-dwelling, post-menopausal women (N = 164) were taught pelvic floor muscle training (PFMT) and bladder training (BT) and followed with surveys for 1 year. Content analysis of open-ended responses coded descriptions of approaches participants used to incorporate PFMT into daily life. Exploratory bivariate and logistic regression analyses determined predictors of approach used and adherence. Results indicate women incorporated PFMT into their lives using either a routine or ad hoc approach. Those using a routine approach at 3 months were 12 times more likely to adhere (odds ratio [OR] = 12.4, confidence interval [CI] = 4.0-38.8, p < .001) at a high level at 3 months and significantly more likely to maintain that level 12 months post-intervention (OR = 2.7, CI = 1.2-6.0, p < .014). Practicing BT was related to high adherence.


Subject(s)
Behavior Therapy , Exercise Therapy , Patient Compliance/psychology , Urinary Incontinence/prevention & control , Urinary Incontinence/psychology , Aged , Aged, 80 and over , Behavior Therapy/methods , Chi-Square Distribution , Confidence Intervals , Exercise Therapy/methods , Female , Follow-Up Studies , Humans , Logistic Models , Middle Aged , Multivariate Analysis , Nursing Methodology Research , Odds Ratio , Patient Education as Topic/methods , Pelvic Floor , Prevalence , Qualitative Research , Randomized Controlled Trials as Topic , Surveys and Questionnaires , Toilet Training , Urinary Incontinence/diagnosis
8.
Int Urol Nephrol ; 38(2): 255-61, 2006.
Article in English | MEDLINE | ID: mdl-16868693

ABSTRACT

OBJECTIVES: Questions exist about using mass mailings to recruit representative samples to participate in clinical trials. The MESA Prevention Study (Medical, Epidemiologic and Social Aspects of Aging), a randomized controlled clinical trial to prevent urinary incontinence (UI), utilized a mass mailing recruitment procedure to recruit a representative sample of women to participate in a behavioral modification program. This paper seeks to expand the literature of mass mailing recruitment strategies for prevention studies by describing the procedures used to recruit healthy, continent, post-menopausal women aged 55-80 years. METHODS: Sociodemographic data collected from recruited subjects is compared with on-line national census data to evaluate the representativeness of the sample recruited from a purchased mailing list. RESULTS: The mass mailing procedure resulted in 3.3% positive response. Of those that returned a positive response, 37.6% were deemed eligible at first screening. Comparisons of study demographic data with state and county census data indicate that the sample obtained was representative of the communities. CONCLUSIONS: The mass mailing strategy was an effective means of recruiting a representative sample of women, aged 55-80. Short falls and recommendations for successful community sample recruitment strategies for clinical trials in older adult women are elaborated upon.


Subject(s)
Patient Selection , Postal Service , Randomized Controlled Trials as Topic/methods , Residence Characteristics , Urinary Incontinence/prevention & control , Aged , Aged, 80 and over , Behavior Therapy , Female , Humans , Middle Aged , Research Design
9.
Article in English | MEDLINE | ID: mdl-16237512

ABSTRACT

This study describes acquisition of knowledge and motor skill in bladder training (BT) and pelvic floor muscle training (PFMT) and adherence following a behavioral modification program (BMP). Essentially continent (0-5 episodes in past year) community-dwelling older women (n = 359) were randomized to treatment (n = 164), a 2-h group education session supplemented by one brief individualized session of approximately 10 min, or control (n = 195), no instruction, and followed for 12 months. Knowledge, motor skill, and adherence to the BMP were documented. Changes in pelvic muscle function and voiding interval were used to validate self-reported adherence. Following group instruction, mean BT and PFMT knowledge was 90 and 86%, respectively; 68% demonstrated correct PFMT technique without additional instruction, 29% required brief instruction, and 3% were unable to learn PFMT technique. Adherence ranged from 63 to 82% for PFMT and 58 to 67% for BT. Group instruction supplemented with brief individual instruction as needed is an effective teaching method for BT and PFMT.


Subject(s)
Behavior Therapy/methods , Exercise Therapy , Urinary Incontinence/prevention & control , Urinary Incontinence/psychology , Aged , Aged, 80 and over , Female , Humans , Knowledge of Results, Psychological , Middle Aged , Motor Skills , Pelvic Floor/physiology , Psychotherapy, Group/methods , Surveys and Questionnaires , Urinary Bladder/physiology , Urinary Incontinence/physiopathology
10.
Nature ; 428(6982): 493-521, 2004 Apr 01.
Article in English | MEDLINE | ID: mdl-15057822

ABSTRACT

The laboratory rat (Rattus norvegicus) is an indispensable tool in experimental medicine and drug development, having made inestimable contributions to human health. We report here the genome sequence of the Brown Norway (BN) rat strain. The sequence represents a high-quality 'draft' covering over 90% of the genome. The BN rat sequence is the third complete mammalian genome to be deciphered, and three-way comparisons with the human and mouse genomes resolve details of mammalian evolution. This first comprehensive analysis includes genes and proteins and their relation to human disease, repeated sequences, comparative genome-wide studies of mammalian orthologous chromosomal regions and rearrangement breakpoints, reconstruction of ancestral karyotypes and the events leading to existing species, rates of variation, and lineage-specific and lineage-independent evolutionary events such as expansion of gene families, orthology relations and protein evolution.


Subject(s)
Evolution, Molecular , Genome , Genomics , Rats, Inbred BN/genetics , Animals , Base Composition , Centromere/genetics , Chromosomes, Mammalian/genetics , CpG Islands/genetics , DNA Transposable Elements/genetics , DNA, Mitochondrial/genetics , Gene Duplication , Humans , Introns/genetics , Male , Mice , Models, Molecular , Mutagenesis , Polymorphism, Single Nucleotide/genetics , RNA Splice Sites/genetics , RNA, Untranslated/genetics , Rats , Regulatory Sequences, Nucleic Acid/genetics , Retroelements/genetics , Sequence Analysis, DNA , Telomere/genetics
11.
J Urol ; 171(3): 1165-71, 2004 Mar.
Article in English | MEDLINE | ID: mdl-14767293

ABSTRACT

PURPOSE: We determined whether a behavioral modification program (BMP) taught to groups of continent older women would decrease the incidence of urinary incontinence, increase pelvic muscle strength and improve voiding control. MATERIALS AND METHODS: We performed a randomized, controlled trial comparing a BMP treatment group to a control, no treatment group in ambulatory, postmenopausal, continent women (0 to 5 days of incontinent episodes in the previous year) 55 years and older who were followed for 12 months. Qualified volunteers from 4 Michigan counties were randomly assigned to a control or a treatment group, consisting of a 2-hour classroom presentation on BMP followed 2 to 4 weeks later with individualized evaluation to test knowledge, adherence and skills in behavioral techniques, and brief reinforcement of the technique as needed. Followup was done by telephone and mail every 3 months except month 12, when all participants underwent final clinical evaluation. Outcome measures were continence status, pelvic floor muscle strength and voiding frequency/intervoid interval. RESULTS: A total of 195 control and 164 treated participants completed the study. Baseline data on the 2 groups were not statistically different. At 12 months the treatment group was statistically significantly better than the control group in continence status (p = 0.01), pelvic muscle strength (pressure score p = 0.0003 and displacement score p <0.0001), improved voiding frequency (p <0.0001) and intervoid interval (p <0.0001). CONCLUSIONS: To our knowledge we report the first randomized, controlled trial of BMP for preventing urinary incontinence in older women. It demonstrated feasibility and efficacy in improving continence status, pelvic muscle strength and voiding control as long as a year after treatment.


Subject(s)
Behavior Therapy , Urinary Incontinence/prevention & control , Aged , Aged, 80 and over , Female , Humans , Middle Aged , Urinary Incontinence/physiopathology , Urination
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