[Differences in self-harm among adolescents and young adults with autism spectrum disorder: a gender-based approach]. / Diferencias en la autolesión en adolescentes y adultos jóvenes con trastorno del espectro autista: un enfoque de género.

INTRODUCTION: Self-harm in children and young people with autism spectrum disorder (ASD) poses risks to their physical well-being, negatively impacts their quality of life and that of their families, and presents challenges to their integration into school and social environments. This study aimed to investigate possible differences in terms of gender between adolescents and young adults with autism admitted to the neurodevelopmental unit of ITA Argentona due to non-suicidal self-harming behaviour. PATIENTS AND METHODS: A sample of 50 patients with ASD, whose ages ranged from 14 to 27 years, who were treated in the ITA Argentona neurodevelopmental unit. The methodology adopted consisted of a non-causal correlational cross-sectional study, for which the Autism Diagnostic Observation Schedule, second edition, and the Autism Diagnostic Interview-Revised were administered, as well as the Inventory of Statements About Self-injury. RESULTS: The results obtained revealed significant and positive correlations between sex and certain types of self-harm (burning, pulling hair and carving) and the motivations or functions that the participants report for engaging in non-suicidal self-harm. CONCLUSIONS: Although the study concluded that there is no substantially greater likelihood of one sex in particular engaging non-suicidal self-harm, significant differences were identified in terms of the specific types of self-harm, and the motivations or functions associated with these non-suicidal self-harming behaviours.

TITLE: Diferencias en la autolesión en adolescentes y adultos jóvenes con trastorno del espectro autista: un enfoque de género.Introducción. Las autolesiones en niños y jóvenes con trastorno del espectro autista (TEA) representan riesgos para su bienestar físico, impactan negativamente en su calidad de vida y la de sus familias, y presentan desafíos para su integración en entornos escolares y sociales. El propósito de este estudio fue investigar posibles diferencias por sexos entre adolescentes y jóvenes adultos con autismo que ingresaron en la unidad de neurodesarrollo de ITA Argentona debido a autolesiones no suicidas. Pacientes y métodos. Muestra de 50 pacientes con TEA, cuyas edades oscilaron entre los 14 y los 27 años, y que fueron atendidos en la unidad de neurodesarrollo de ITA Argentona. La metodología adoptada consistió en un estudio trasversal correlacional de tipo no causal, para el cual se administraron la escala de observación para el diagnóstico del autismo, segunda edición, y la Autism Diagnostic Interview-Revised, así como el inventario de declaraciones sobre autolesión. Resultados. Los resultados obtenidos revelaron correlaciones significativas y positivas entre el sexo y ciertos tipos de autolesiones (quemarse, tirarse del pelo o grabarse letras) y las motivaciones o funciones que las personas refieren para llevar a cabo autolesiones no suicidas. Conclusiones. Aunque se concluye que no existe una probabilidad sustancialmente mayor de que un sexo en particular respalde autolesiones no suicidas, se pudieron identificar diferencias significativas en cuanto a los tipos específicos de autolesiones y las motivaciones o funciones asociadas a estas conductas autolesivas no suicidas.

Examining Clinical Presentation and Workup of Veterans with Irritable Bowel Syndrome in a Single Medical Centre: A Case Series.

Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction (DGBI) that affects about 10% of the adult population in the United States. IBS pathoetiology understanding has evolved and clinical management improved despite the underdevelopment of diagnostics. Within the Veterans Affairs (VA) system, the prevalence and impact of DGBIs are high. Yet there is a paucity of information on the patient demographic features. Our team examined the history and workup of patients referred to an IBS clinic within the VA's gastroenterology service through a systematic case series study to begin a quality improvement initiative.

Supresión de un cuadro de micosis fungoide recurrente con distribución zosteriforme mediante tratamiento de mantenimiento con valaciclovir / Successful Suppression of Recurrent Zosteriform Mycosis Fungoides With Maintenance Valacyclovir

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Pruritic arthropod bite-like papules in T-cell large granular lymphocytic leukaemia and chronic myelomonocytic leukaemia.

T-cell large granular lymphocytic leukaemia (T-LGLL) is a clinically indolent mature T-cell neoplasm characterized by a monoclonal population of CD3+ CD8+ cytotoxic T cells, which usually presents as neutropenia, anaemia and thrombocytopenia. Chronic myelomonocytic leukaemia (CMML) is a clonal haematopoietic disorder with features of both a myeloproliferative neoplasm and myelodysplastic syndrome (MDS). Patients with CMML exhibit a persistent peripheral blood monocytosis in addition to myelodysplastic features. Because of the rarity of T-LGLL, its cutaneous manifestations are poorly documented, but include vasculitis, vasculopathy, persistent ulcerations, generalized pruritus and disseminated granuloma annulare. Various types of skin lesions have been observed in patients with CMML and reportedly occur in approximately 10% of cases. We report the extraordinary case of a patient with MDS who developed T-LGLL, and subsequently the MDS progressed to CMML. The patient then developed diffuse arthropod bite-like papules and intractable pruritus.

Colonoscope length and procedure efficiency.

We reviewed 195 colonoscopies to determine whether procedure efficiency differed with the use of an intermediate-length (135 cm) colonoscope compared with a long (165 cm) colonoscope. The cecum was intubated with the 135-cm scope in 92.6% of procedures and with the 165-cm colonoscope in 96.8% of procedures (chi 2 method, p = 0.26). The mean procedure duration was 36.7 min for 107 complete procedures performed with the 135-cm colonoscope and 48.4 min for 55 examinations using the 165-cm colonoscope (t test, p < 0.001). Colonoscopy with the 135-cm instrument required mean meperidine and midazolam doses of 59.9 mg and 1.8 mg, respectively, compared with doses of 69.1 mg and 2.0 mg, respectively, with the 165-cm colonoscope. The differences were not significant. Although the cecal intubation rate is slightly less for the 135-cm colonoscope, insertion takes significantly less time and is probably more comfortable for the patient than with the 165-cm colonoscope.