ABSTRACT
OBJECTIVE: To report long-term ophthalmological sequelae in extremely premature infants at 5 years and to determine the relationship between neonatal variables (including retinopathy of prematurity; ROP) and the 5 year ophthalmological outcome of these infants. METHODOLOGY: The study cohort comprised 84 surviving infants born with a birthweight < 1000 g or gestational age < 28 weeks from June 1985 to December 1989. All infants had an ophthalmological assessment between 34 and 40 weeks post conceptional age to document grade of ROP and were assessed at 5 years of age for fundoscopy, visual acuity, refractive error and ocular mobility. RESULTS: Of the 84 long-term survivors 69 (82%) were formally assessed at 5 years. Overall, 30 (43%) had some form of ocular disorder. Nineteen (27%) had reduced visual acuity of < 6/6 and three of these were blind. Myopia > -0.5 dioptre was noted in eight (12%), hypermetropia > or = 2.0 dioptre in five (8%), astigmatism in seven (11%) and strabismus was present in nine (14%) of the cohort. There was a significant relationship (P < 0.0001) between the incidence of ocular disorders and ROP. However, even those premature children without ROP had a 31% incidence of ocular disorder at 5 years. CONCLUSION: Long-term ophthalmological follow-up is recommended in all extremely premature infants regardless of the presence of ROP in the neonatal period.
Subject(s)
Eye Diseases/epidemiology , Infant, Premature , Infant, Very Low Birth Weight , Refractive Errors/epidemiology , Australia/epidemiology , Child, Preschool , Cohort Studies , Diagnostic Techniques, Ophthalmological , Eye Diseases/etiology , Eye Diseases/therapy , Female , Follow-Up Studies , Gestational Age , Humans , Incidence , Infant, Newborn , Male , Prospective Studies , Refractive Errors/etiology , Refractive Errors/rehabilitation , Retinopathy of Prematurity/diagnosis , Retinopathy of Prematurity/epidemiology , Retinopathy of Prematurity/therapy , Risk Factors , Treatment Outcome , Visual AcuityABSTRACT
A case of spontaenously resolving bilateral papilloedema in an obese 38 year old woman subject to cluster headache is reported. The aetiology of the condition remained obscure after neurological and biochemical investigation.
