Subject(s)
Mitral Valve Prolapse/diagnosis , Adolescent , Adult , Aged , Child , Echocardiography , Electrocardiography , Female , Humans , Male , Middle Aged , Mitral Valve Prolapse/etiologySubject(s)
Echocardiography , Heart/drug effects , Nitroglycerin/pharmacology , Adult , Coronary Disease/physiopathology , Diastole , Female , Heart/physiopathology , Heart Ventricles/drug effects , Heart Ventricles/physiopathology , Humans , Hypertension/physiopathology , Male , Middle Aged , SystoleABSTRACT
Hemodynamic response of nifedipine in 11 patients with congestive heart failure was examined. Thirty minutes after sublingual administration of nifedipine, CI and SVI were increased together with a decrease in PAEDP and TSVRI. The increase in CI was proportional to the decrease in TSVRI. Twenty-four hours after continuous administration of nifedipine, however, six of 11 patients did not show the improvement of left ventricular function. These results indicate that sublingual administration of nifedipine is effective in the short-term therapy of the patients with a markedly decreased cardiac output and an increased systemic vascular resistance.
Subject(s)
Heart Failure/drug therapy , Hemodynamics/drug effects , Nifedipine/pharmacology , Pyridines/pharmacology , Administration, Oral , Aged , Blood Pressure/drug effects , Calcium/antagonists & inhibitors , Cardiac Output/drug effects , Female , Heart Failure/physiopathology , Humans , Male , Middle Aged , Nifedipine/administration & dosage , Nifedipine/therapeutic use , Tongue , Vascular Resistance/drug effects , Vasodilator Agents/pharmacologySubject(s)
Echocardiography , Adult , Diastole , Female , Heart Diseases/physiopathology , Heart Ventricles/physiopathology , Hemodynamics , Humans , Male , SystoleABSTRACT
A case of Fabry's disease with pulmonary regurgitation is reported, and the cause of valvular involvement, the electrophysiological mechanism of the short PR interval, and the usefulness of the endomyocardial biopsy method in an attempt to establish the diagnosis in Fabry's disease have been discussed.
