Hypopharyngeal neurinoma: report of two cases.

Hypopharyngeal neurinoma: report of two cases. Acta Otolaryngol 2002; Suppl 547: 100-103. Hypopharyngeal neurinoma is a very rare disease and we found reports of only seven cases in the literature. Laryngomicrosurgery (LMS) and lateral neck exploration are two operating methods for hypopharyngeal neurinoma. Of the seven reported cases, the operating method was mentioned in six: two were operated on using LMS and four using the neck exploration method. It is necessary to select the operating method based on the size of the tumor, the existence of a stem, the risk of bleeding, etc. It is difficult to trace the original nerve of the tumor and this could not be done conclusively in the previous reports.

Clinical review of thyroid malignant tumor.

We reviewed the files of 120 patients with thyroid malignant tumor treated in our department between July 1971 and December 1996. Clinical features, pathological diagnosis, radiographic findings, treatment and prognosis were studied. The number of patients treated gradually increased over time in both the otorhinolaryngology and surgery departments. Papillary carcinoma (n = 101) was the most common pathology, followed by follicular carcinoma (n = 16). Both 5- and 10-year survival rates were 92.7% for the entire group, 93.8% for cases of follicular carcinoma and 92.1% for cases of papillary carcinoma. Although thyroid tumor is undoubtedly one of the malignant head and neck tumors associated with an excellent prognosis, some patients remain resistant to cure in the long term. Some tumors are highly malignant and are difficult to control. The management of these patients is an important subject of future research.

[Three-dimensional analysis of human Ebner's gland].

We analyzed changes in Ebner's gland with aging by 3-dimensional analysis to determine the relationship between the gland and the sense of taste. Samples were collected from Circumvallate papillae of the tongue in autopsied cases. After dehydration, samples were embedded in paraffin and cut into slices 5 microns thick for every 100 microns. Hematoxylin-Eosin staining was done. The section was photographed in black and white and printed. Three tissues, circumvallate papillae, epithelium, and Ebner's gland were identified and traced on an OHP sheet and imput to a computer. The cubic volume of Ebner's gland was measured by Cosmozone 2SA 3-dimensional analysis software by and acinar cell occupancy I-BAS one imaging analysis. A total of 60 cases from age groups in them 30s, 40s, 50s, 60s, 70s, and 80s were used. Each group contains 5 men and 5 women. The mean cubic volume of Ebner's gland in the 30s was 67.0 mm3, in the 40s was 64.6 mm3, in the 50s was 59.8 mm3, in the 60s was 39.2 mm3, in the 70s was 33.9 mm3, and in the 80s was 30.4 mm3. Statistical analysis showed a significant difference in Ebner's gland cubic volume between age groups at p < 0.01. In acinar cell occupancIEs the coefficient of correlation was -0.858 in men and -0.838 in women with the correlation diagram showing a negative correlation. The acinar cell occupancy decreases with age for the presumed acinar cell volume in the Ebner's gland, the coefficient of correlation was -0.929 in men and -0.854 in women, with the correlation diagram showing a negative correlation. The presumed acinar cell volume decreases with age. We concluded that Ebner's gland is concerned indirectly with diminished sensitivity of the sense of taste with aging.